Xaira Therapeutics is an integrated biotechnology company driving advances in artificial intelligence to learn the language of life and transform how we treat disease. The company seeks to rethink the drug discovery and development process from end-to-end by bringing together leading talent across three core areas: machine learning research to better understand biology, expansive data generation to power new models, and robust therapeutic product development to treat disease. Xaira is headquartered in the San Francisco Bay Area.

Industry: Biotechnology Research
Company Size: 51-200 employees

Xaira Therapeutics

Savvy Admin PROD

**About Xaira Therapeutics **

Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London.

**About the Role **

We are building foundation models for biological systems, focusing on learning from complex, multimodal data. Our approach combines representation learning and generative modeling to capture structure, variation, and latent organization in high-dimensional settings. We work with both image-based data and high-dimensional molecular (omics) measurements, treating them as complementary views of the same underlying system. Our goal is to develop models that can both encode rich representations and generate or infer missing aspects from partial observations.

**What You’ll Do **

- Develop multimodal foundation models spanning image and molecular data

- Design approaches that unify representation learning and generative modeling

- Train large-scale models on structured, high-dimensional datasets

- Explore cross-modal alignment, prediction, and generation

- Build scalable systems for data processing, training, and evaluation

- Work in a research-driven environment with evolving problem definitions

**What We’re Looking For **

Strong background in deep learning, especially in modern architecture

- Experience with representation learning (self-supervised, contrastive, masked modeling, etc.)

- Experience with generative modeling (diffusion, autoregressive models, VAEs, or related approaches)

- Proficiency in Python, ML frameworks, and CI/CD (PyTorch, JAX, etc.)

Relevant Experience

- Work on multimodal learning or cross-domain representation learning

- Experience with image data, molecular / omics-like data, or both

- Familiarity with large-scale training

Bonus

- Exposure to biological or scientific datasets

- Experience with paired or partially aligned multimodal data

- Comfortable working in open-ended, evolving problem spaces

**Compensation **

We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants. We offer a competitive package that includes base salary, bonus, and equity. The base pay range for this position is expected to be $170,000 - $240,000 annually; however, the base pay offered may vary depending on the market, job-related knowledge, skills and capabilities, and experience.

Xaira Therapeutics an equal-opportunity employer. We believe that our strength is in our differences. Our goal to build a diverse and inclusive team began on day one, and it will never end.

TO ALL RECRUITMENT AGENCIES: Xaira Therapeutics does not accept agency resumes. Please do not forward resumes to our jobs alias or employees. Xaira Therapeutics is not responsible for any fees related to unsolicited resumes.

AI Scientist - Biomedical Multimodal Modeling

**About Xaira Therapeutics **

Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London.

**About the Role **

- We are seeking a highly motivated Scientist with strong hands-on experience in assay development, immunology, and cell biology to support the discovery and characterization of novel therapeutic antibodies. This role is ideal for an experimentalist who enjoys independently designing and executing complex biological assays, troubleshooting workflows, and generating high-quality data to support drug discovery programs.

- The ideal candidate has deep experience developing functional antibody assays and is comfortable operating in fast-paced, evolving research environments. You will work closely with cross-functional teams spanning protein engineering, automation, and computational biology to support target validation and therapeutic development efforts.

**Key Responsibilities **

- Independently design, execute, and optimize functional antibody assays to support discovery and characterization efforts

- Develop and run cell-based assays focused on immune activation, cell signaling, and cell-cell interaction biology

- Design experimental controls, analyze assay performance, and troubleshoot workflows to ensure robust and interpretable data generation

- Perform hands-on molecular and cellular biology experiments, including mammalian cell culture and assay execution

- Support characterization of antibody candidates through functional and mechanistic studies

- Collaborate cross-functionally with protein engineering, automation, and computational teams to support data generation and experimental workflows

- Clearly document experiments, analyze results, and communicate findings to project teams

**Required Qualifications **

- B.S. or M.S. with 5–10 years of relevant industry experience

- Strong hands-on experience developing and executing functional biological assays

- Experience with antibody-related assays, including immune activation, signaling, or cell-cell interaction systems

- Strong background in mammalian cell culture and cell-based assay workflows

- Experience designing experiments, selecting controls, troubleshooting assays, and interpreting complex datasets

- Hands-on molecular biology experience, including cloning or related techniques

- Demonstrated ability to independently drive experiments and generate high-quality data

- Strong organizational skills and attention to detail

**Preferred Qualifications **

- Experience working in antibody discovery or therapeutic development environments

- Familiarity with T-cell activation or immune profiling assays

- Experience working with data-rich or high-throughput experimental workflows

- Comfort operating in collaborative, fast-paced, and evolving research environments

- Experience partnering with automation or computational biology teams

**Compensation: **Annual

We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants. We offer a competitive package that includes base salary, bonus, and equity. The base pay range for this position is expected to be $101,000 - $126,000 annually; however, the base pay offered may vary depending on the market, job-related knowledge, skills and capabilities, and experience.

Xaira Therapeutics an equal-opportunity employer. We believe that our strength is in our differences. Our goal to build a diverse and inclusive team began on day one, and it will never end.

TO ALL RECRUITMENT AGENCIES: Xaira Therapeutics does not accept agency resumes. Please do not forward resumes to our jobs alias or employees. Xaira Therapeutics is not responsible for any fees related to unsolicited resumes.

Senior Research Associate/ Associate Scientist, Platform and Assay Development

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