Scientist
5+ years
Worcester, MA
Contract
Onsite
1 month ago
About the role
Cell Line Engineer (Contract – 1 Year + Extension)
Location: Worcester, MA
Pay: $45–46/hr target
Position Summary
We are seeking a Cell Line Engineer to join the Cell Line Engineering group within Biotherapeutics Discovery. This role focuses on mammalian cell culture, cell line engineering, and cell-based assay development supporting therapeutic discovery programs.
The individual will work under the supervision of a senior scientist and contribute to execution-heavy wet lab work, including cell line development, genome engineering, and assay support, along with lab organization and inventory management.
Key Responsibilities
Required Qualifications
Preferred Qualifications
Education
Top Must-Have Skills
Location: Worcester, MA
Pay: $45–46/hr target
Position Summary
We are seeking a Cell Line Engineer to join the Cell Line Engineering group within Biotherapeutics Discovery. This role focuses on mammalian cell culture, cell line engineering, and cell-based assay development supporting therapeutic discovery programs.
The individual will work under the supervision of a senior scientist and contribute to execution-heavy wet lab work, including cell line development, genome engineering, and assay support, along with lab organization and inventory management.
Key Responsibilities
- Mammalian cell culture (immortalized, cancer, and primary cell lines)
- Development and maintenance of engineered cell lines for antibody discovery and assay development
- Cell line engineering (KO, KI, OE)
- Cell-based assays and functional biology experiments
- Flow cytometry (FACS analysis and cell sorting)
- Receptor density and protein expression analysis
- DNA construct design and molecular cloning support
- Use of fluorescent and luminescent assay systems
- CRISPR-based gene editing (preferred but highly valued)
- Lab operations support (inventory management, ordering, materials organization)
- Cell line banking, expansion, and coordination across sites
- Digitization and organization of cell line inventory systems
Required Qualifications
- 2–5+ years of industry experience (required)
- Strong hands-on experience with mammalian cell culture (2–3+ years required)
- Proven experience in cell line development / engineering (required)
- At least 1+ year of flow cytometry experience (required)
- Experience with cell-based assays
- Strong documentation, communication, and organizational skills
- Ability to contribute immediately in a fast-paced lab environment
Preferred Qualifications
- CRISPR/Cas9 gene editing experience (1+ year strongly preferred)
- Experience with genome engineering (KO/KI/OE)
- Prior biotech/pharma industry experience (preferred over academic)
Education
- MS + 2 years industry experience (preferred)
- BS + 2–3 years industry experience (acceptable)
- PhD not preferred for this role
Top Must-Have Skills
- Mammalian cell culture
- Cell line engineering (KO/KI/OE)
- Flow cytometry (FACS)
- Cell-based assays
- CRISPR gene editing (preferred)
Skills
Science