People Operations Manager New York City | Full-time | In-Office About the Company A rapidly growing AI healthtech startup is redefining how life sciences organizations commercialize therapeutics. The company is building AI-powered infrastructure that enables pharmaceutical marketers to launch campaigns at significantly greater speed and scale. Over the past year, the team has partnered with leading life sciences manufacturers and supports more than 50 pharmaceutical brands across some of the largest pharma organizations globally. The company operates at the forefront of AI innovation, leveraging large language models and advanced frameworks to transform pharmaceutical marketing. Backed by top-tier investors and experienced healthcare technology founders, the organization is entering an exciting phase of growth and team expansion. About the Role The company is seeking a People Operations Manager to serve as a key operational and cultural leader within the organization. This hybrid role combines HR responsibilities with office operations and executive support, helping ensure the team operates efficiently while maintaining a strong in-office culture. This position will partner closely with the founders to build scalable systems, people processes, and team rituals that support a high-performing startup environment. This is an in-person role ideal for someone who thrives on ownership, moves quickly, and proactively solves problems before they arise. Location New York City — in-office 5 days per week Hours Monday–Thursday: 9:00 AM – 7:00 PM Friday: 9:00 AM – 5:00 PM Responsibilities People & HR
Write and maintain the employee handbook, including policies, culture, and people practices
Support onboarding processes to ensure a strong new hire experience
Serve as a trusted resource for employee questions, concerns, and career development
Manage and execute performance review cycles and ensure manager participation
Drive employee engagement, retention, and culture initiatives
Lead planning and execution of the company’s annual retreat
Office Operations & Executive Support
Manage day-to-day operations of the NYC office, including vendors, facilities, and supplies
Coordinate complex executive calendars and scheduling across time zones
Provide administrative support to founders, including travel coordination and expense management
Act as the primary point of contact for office-related needs
Coordinate team events, meetings, and offsites
Manage onboarding logistics, including workspace and equipment setup
Partner with finance and legal teams on contracts, invoices, and office spend
Identify operational gaps and proactively implement improvements
Qualifications
3+ years of experience in HR, executive support, office management, or a combination of these areas
Exceptional organizational skills and attention to detail
Strong written and verbal communication skills
Ability to build trust across all levels of an organization
Proactive, solutions-oriented mindset with strong ownership mentality
Ability to handle sensitive and confidential information with discretion
Comfortable working in a fast-paced, highly collaborative startup environment
Preferred
Experience helping scale people operations within an early-stage or high-growth company