Senior Scientist I, Analytical & Purification Sciences
North Chicago, IL
Full-time
Onsite
1 month ago
About the role
Company Description
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube.
Job Description
The Analytical and Purification Sciences (APS) group has an exciting opportunity for a Senior Scientist to join the Technology and Therapeutic Platforms organization within Discovery Research at AbbVie.The APS group provides enabling technologies to support Discovery Medicinal Chemistry initiatives. The scientist will execute compound purification using preparative HPLC and/or SFC and devise innovative solutions to complex analytical and separation problems through the implementation of sophisticated instrumentation. The candidate will act as a lead scientist in his/her area of expertise on one or more projects and critically evaluate relevant scientific advances and integrate this knowledge into research programs.
Key Responsibilities
Qualifications
Basic Qualifications
Preferred
Key Leadership Competencies
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:
Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.Theamountandavailabilityof anybonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company'ssoleandabsolutediscretion unless and until paid andmay bemodifiedat the Companys sole and absolute discretion, consistent withapplicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
https://www.abbvie.com/join-us/reasonable-accommodations.html
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube.
Job Description
The Analytical and Purification Sciences (APS) group has an exciting opportunity for a Senior Scientist to join the Technology and Therapeutic Platforms organization within Discovery Research at AbbVie.The APS group provides enabling technologies to support Discovery Medicinal Chemistry initiatives. The scientist will execute compound purification using preparative HPLC and/or SFC and devise innovative solutions to complex analytical and separation problems through the implementation of sophisticated instrumentation. The candidate will act as a lead scientist in his/her area of expertise on one or more projects and critically evaluate relevant scientific advances and integrate this knowledge into research programs.
Key Responsibilities
- Maintain a high level of productivity in the laboratory setting.
- Collaborate with medicinal chemistry teams through developing methods and providing technical guidance to solve analytical and purification problems.
- Innovate within the Analytical and Purification Sciences group to develop efficient workflows for sample prioritization and client communication.
- Execute compound purification on milligram to gram scale using preparative HPLC and/or SFC, to support small molecule drug discovery projects.
- Maintain analytical and preparative HPLC and SFC instrumentation and independently troubleshoot instrument problems.
- Proactively mentor colleagues in technical development and in establishing positive and productive working relationships.
- May supervise one or more direct reports.
- Keep abreast of current literature and industry trends to assess new approaches in high-throughput purification and analytical technologies. Propose and implement new initiatives/directions for the team.
- Maintain a highly productive purification workflow, establish strategies that effectively optimize available equipment and personnel, and promote efficiency and enable new paradigms in Medicinal Chemistry.
- Demonstrate a high degree of responsibility in maintaining scientific standards and safe laboratory practices.
- Keep accurate and current records of research and/or project related activities according to AbbVie policies.
Qualifications
Basic Qualifications
- PhD or MS in Organic Chemistry, Analytical Chemistry, or related fields with 0+years (PhD); 8+ years (MS); or10+ years (BS) of postdoctoral and/or pharmaceutical industry experience.
- Hands-on experience with analytical and preparative scale HPLC and/or SFC.
- Ability to operate and troubleshoot a variety of analytical and preparative instrumentation hardware and software.
- Knowledge of synthetic organic chemistry and the ability to communicate effectively with medicinal chemistry teams.
- Demonstrated record of achievement in chiral/achiral purification on milligram to gram scale for a variety of programs using multiple approaches and technologies.
- Proven effective written and verbal communication skills and ability to interact with scientists and engineers.
Preferred
- Experience in analytical and purification techniques for peptides.
- Experience of working in a fast-paced purification group and communicating effectively with Medicinal Chemistry teams.
- Experience in reversed-phase separations using HPLC.
- Experience in chiral separations using HPLC and SFC.
- Experience with instrument development, automation, programming, and data analytics.
Key Leadership Competencies
- Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance
- Learns fast, grasps the "essence" and can change course quickly where indicated
- Raises the bar and is never satisfied with the status quo
- Creates a learning environment, open to suggestions and experimentation for improvement
- Embraces the ideas of others, nurtures innovation and manages to reality
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:
- The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at thetimeofthis posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographiclocation,andwemayultimatelypaymore or less than the posted range. This range may bemodifiedin thefuture.
- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.
- This job is eligible toparticipatein our short-term incentiveprograms.
Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.Theamountandavailabilityof anybonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company'ssoleandabsolutediscretion unless and until paid andmay bemodifiedat the Companys sole and absolute discretion, consistent withapplicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
https://www.abbvie.com/join-us/reasonable-accommodations.html