Principal Clinical Scientist (AI Training) About The Role What if your career-long expertise in clinical trial design and regulatory science could directly shape how AI understands and evaluates clinical evidence? We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research workflows. You'll work with cutting-edge AI systems being developed by leading research labs — ensuring the clinical intelligence built into these models meets the standards expected in real-world regulatory environments. This is a fully remote, flexible contract role. No AI background needed — just deep command of clinical research and regulatory science.
Organization: Alignerr
Type: Hourly Contract
Location: Remote
Commitment: 10–40 hours/week
What You'll Do
Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training
Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
Evaluate AI-generated clinical analyses for scientific soundness and alignment with regulatory expectations (FDA, EMA, or equivalent)
Provide expert, structured feedback that improves how AI models reason about clinical trial data, endpoints, and outcomes
Help define quality standards for clinical data used across frontier AI research projects
Who You Are
Senior-level experience designing clinical trial protocols for regulatory submission
Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent bodies
Strong background in clinical research methodology, biostatistics, translational science, or a closely related field
Naturally rigorous and detail-oriented — you hold data and analysis to a high standard
Able to communicate expert clinical judgment clearly in written feedback
Comfortable working independently in a self-directed, asynchronous environment
Nice to Have
Prior experience with data annotation, data quality evaluation, or AI model evaluation workflows
Background in pharmacology, clinical pharmacokinetics, or outcomes research
Experience working across multiple therapeutic areas or regulatory jurisdictions
Familiarity with AI tools or structured evaluation platforms
Why Join Us
Work directly on frontier AI systems making a real impact on clinical and biomedical research
Fully remote and flexible — work when and where it suits you
Freelance autonomy with the structure of meaningful, expert-level work
Influence how AI understands and evaluates real-world clinical evidence at a foundational level
Potential for ongoing work and contract extension as new projects launch
Global collaboration with world-class AI researchers and scientists