Principal Clinical Scientist
Denver, CO
Contract
Remote
1 month ago
About the role
Principal Clinical Scientist (AI Training)
About The Role
What if your years of clinical research expertise could directly influence how AI understands and evaluates medical evidence for millions of people worldwide? We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research workflows — ensuring that the clinical reasoning embedded in next-generation AI systems meets the standards that matter most in real-world medicine.
This is a fully remote, flexible contract role designed for experienced clinical scientists who want to work at the frontier of biomedical AI without leaving their domain expertise behind.
What You'll Do
Who You Are
Nice to Have
Why Join Us
About The Role
What if your years of clinical research expertise could directly influence how AI understands and evaluates medical evidence for millions of people worldwide? We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research workflows — ensuring that the clinical reasoning embedded in next-generation AI systems meets the standards that matter most in real-world medicine.
This is a fully remote, flexible contract role designed for experienced clinical scientists who want to work at the frontier of biomedical AI without leaving their domain expertise behind.
- Organization: Alignerr
- Type: Hourly Contract
- Location: Remote
- Commitment: 10–40 hours/week
What You'll Do
- Design and critically review clinical trial protocols used to generate high-quality, regulatory-grade datasets for AI training
- Interpret and audit clinical trial results, ensuring accuracy, consistency, and alignment with regulatory expectations (FDA, EMA, or equivalent)
- Evaluate AI-generated clinical analyses for scientific soundness and methodological rigor
- Provide expert, structured feedback that directly shapes how AI models reason about clinical trial data, outcomes, and evidence
- Flag gaps, errors, or inconsistencies in AI outputs from a senior clinical science perspective
- Work independently and asynchronously — fully on your own schedule
Who You Are
- Senior-level experience designing clinical trial protocols for regulatory submission
- Deep expertise interpreting clinical data for major regulatory agencies (FDA, EMA, or equivalent)
- Strong grounding in clinical research methodology, biostatistics, or translational science
- Meticulous and rigorous — you hold AI-generated content to the same standards you'd apply in a real submission
- Clear, concise written communicator who can articulate expert feedback effectively
- Self-directed and reliable when working independently
Nice to Have
- Prior experience with data annotation, data quality review, or evaluation systems
- Familiarity with AI tools or clinical data platforms
- Background spanning oncology, rare disease, cardiovascular, or other regulated therapeutic areas
- Experience in translational research or early-phase clinical development
Why Join Us
- Work directly on frontier AI systems that are reshaping clinical and biomedical research
- Influence how AI understands, evaluates, and reasons about real-world clinical evidence
- Fully remote and flexible — work when and where it suits you
- Freelance autonomy with the structure of meaningful, high-impact expert work
- Collaborate with world-leading AI research teams and labs
- Potential for ongoing work and contract extension as new projects launch
Skills
Technology, Information and Internet