6 - 10 years
Andover, MA
Contract
Onsite
1 month ago
About the role
ROLE SUMMARY
We are seeking two highly motivated scientists to support the upstream mammalian process development in a laboratory environment. This role focuses on hands-on bioreactor operations, mammalian cell culture, and experimental execution to support biologics development (e.g., monoclonal, bispecific, and Tri specific antibodies).
This is a lab-intensive role requiring strong technical expertise, collaboration skills, and the ability to communicate experimental findings effectively.
Key Responsibilities
• Perform hands-on mammalian cell culture using bioreactors (CHO systems)
• Set up, operate, and monitor bench-scale bioreactors
• Design, execute, and analyze experiments
• Maintain accurate lab documentation (lab notebooks, batch records)
• Analyze cell culture performance (cell density, metabolites, nutrients)
• Write experimental plans and technical reports
• Collaborate cross-functionally with upstream (bacterial), downstream, and analytical teams
• Order lab supplies and maintain inventory
• Participate in weekend/on-call rotation as needed
Work Environment
• ~70% lab work / 30% desk-based work
• Primarily in one building, with occasional movement across campus for sample handling
• Team size: ~10 scientists (multiple levels from lab tech to principal scientist)
Required Qualifications (Must-Haves)
• Bachelor’s degree in Biology, Biochemistry, Chemistry, Bioengineering, or related scientific field
• Minimum 3+ years of relevant lab experience (industry preferred; strong academic experience considered)
• Hands-on experience with mammalian cell culture (CHO cells)
• Experience operating bench-scale bioreactors
• Strong aseptic technique experience (required)
• Experience designing and executing experiments independently
• Ability to document work and write technical reports
• Strong communication and teamwork skills
Preferred Qualifications (Nice-to-Haves)
• Experience with perfusion systems (continuous culture)
• Familiarity with bioreactor control systems (e.g., SCADA, DeltaV)
• Experience with electronic lab notebooks (ELN) or LIMS
• Exposure to analytical tools for cell culture monitoring
• Familiarity with statistical analysis software
Additional Details
• No travel required
• Weekend rotation: approximately 1 weekend per month
o Typically 3–4 hours/day (Saturday & Sunday)
o Paid as overtime
• Candidates must be comfortable working in a highly collaborative lab environment
The ideal candidate is:
• Hands-on and technically strong in the lab
• A clear communicator who can share results effectively across teams
• Able to work independently with minimal supervision
• Collaborative and team-oriented
Screening Considerations / Red Flags
• Lack of communication skills or difficulty working in team environments
• Limited or no hands-on bioreactor experience (for experienced candidates)
• Lack of aseptic technique experience
Interview Process
• 1 onsite interview
• Includes 3 x 30-minute sessions with team members
• Typically 4–5 candidates interviewed per role
We are seeking two highly motivated scientists to support the upstream mammalian process development in a laboratory environment. This role focuses on hands-on bioreactor operations, mammalian cell culture, and experimental execution to support biologics development (e.g., monoclonal, bispecific, and Tri specific antibodies).
This is a lab-intensive role requiring strong technical expertise, collaboration skills, and the ability to communicate experimental findings effectively.
Key Responsibilities
• Perform hands-on mammalian cell culture using bioreactors (CHO systems)
• Set up, operate, and monitor bench-scale bioreactors
• Design, execute, and analyze experiments
• Maintain accurate lab documentation (lab notebooks, batch records)
• Analyze cell culture performance (cell density, metabolites, nutrients)
• Write experimental plans and technical reports
• Collaborate cross-functionally with upstream (bacterial), downstream, and analytical teams
• Order lab supplies and maintain inventory
• Participate in weekend/on-call rotation as needed
Work Environment
• ~70% lab work / 30% desk-based work
• Primarily in one building, with occasional movement across campus for sample handling
• Team size: ~10 scientists (multiple levels from lab tech to principal scientist)
Required Qualifications (Must-Haves)
• Bachelor’s degree in Biology, Biochemistry, Chemistry, Bioengineering, or related scientific field
• Minimum 3+ years of relevant lab experience (industry preferred; strong academic experience considered)
• Hands-on experience with mammalian cell culture (CHO cells)
• Experience operating bench-scale bioreactors
• Strong aseptic technique experience (required)
• Experience designing and executing experiments independently
• Ability to document work and write technical reports
• Strong communication and teamwork skills
Preferred Qualifications (Nice-to-Haves)
• Experience with perfusion systems (continuous culture)
• Familiarity with bioreactor control systems (e.g., SCADA, DeltaV)
• Experience with electronic lab notebooks (ELN) or LIMS
• Exposure to analytical tools for cell culture monitoring
• Familiarity with statistical analysis software
Additional Details
• No travel required
• Weekend rotation: approximately 1 weekend per month
o Typically 3–4 hours/day (Saturday & Sunday)
o Paid as overtime
• Candidates must be comfortable working in a highly collaborative lab environment
The ideal candidate is:
• Hands-on and technically strong in the lab
• A clear communicator who can share results effectively across teams
• Able to work independently with minimal supervision
• Collaborative and team-oriented
Screening Considerations / Red Flags
• Lack of communication skills or difficulty working in team environments
• Limited or no hands-on bioreactor experience (for experienced candidates)
• Lack of aseptic technique experience
Interview Process
• 1 onsite interview
• Includes 3 x 30-minute sessions with team members
• Typically 4–5 candidates interviewed per role