Eurofins DiscoverX, the products company of Eurofins Discovery, is committed to enabling and accelerating multi-modality drug discovery and development from discovery to QC lot release. 

For drug discovery and development scientists, Eurofins DiscoverX is the trusted product solutions provider that accelerates research and drug discovery programs with confidence for cytokine receptors, checkpoint receptors, GPCRs, kinases, ion channels, epigenetics, nuclear receptors, and other target families. Eurofins DiscoverX develops and manufactures cutting edge assays, stable cell lines, ready-to-use kits (including bioassays), membrane preps, enzymes, and reagents for small molecule and biologic immuno-oncology, cytotoxicity, compound-target engagement, potency and QC lot release, pharmacotrafficking, and many other applications. These products are developed from 3 R&D and manufacturing centers of excellence – San Francisco Bay Area California (Fremont); St. Louis area, Missouri (St. Charles); and Poitiers, France.

Industry: Biotechnology Research
Company Size: 51-200 employees

Eurofins DiscoverX

Savvy Admin PROD

**Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate. **** ****Eurofins believes it is a global leader in food, environmental, pharmaceutical and cosmetics products testing and in agroscience CRO services. It is also one of the global independent market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, CDMO, advanced material sciences and in the support of clinical studies.**

**In over just 30 years, Eurofins has grown from one laboratory in Nantes, France to over 50,000 staff across a network of more than 900 independent companies in over 50 countries and operating more than 800 laboratories. Eurofins offers a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products, as well as providing innovative clinical diagnostic testing services, as one of the leading global emerging players in specialized clinical diagnostics testing.**

**In 2021, Eurofins generated total revenues of EUR € 6.7 billion, and has been among the best performing stocks in Europe over the past 20 years.**

**Job Description**

**Come join our growing team! Eurofins DiscoverX Products, LLC is a leader in providing innovative solutions and support to the pharmaceutical industry by developing, manufacturing, and commercializing reagents, cell-based assay kits, and profiling and screening services. The holder of this position will be responsible for the development of new cell lines to support product development and client-driven custom projects.**

**Here's what you'll do:**

- Perform cloning and characterization of engineered cell lines using appropriate molecular and cell biology techniques, which may include flow cytometry, qPCR, Western blotting, immunofluorescence, EFC or other functional readouts.

- Design and perform required experiments to optimize and validate diverse cell-based assays intended for sale in our product portfolio or as custom projects for clients with minimal guidance from supervisor to move projects forward.

- Compile data, analyze and write first draft of client reports and prepare client-facing presentations.

- Perform proof-of-concept experiments to validate application of new molecular technologies to the Eurofins DiscoverX platform.

- Perform testing of cell-based assays using Eurofins DiscoverX technology platforms with client molecules and record results in company database.

- Prepare and present experimental data at group laboratory meetings.

- Work diligently to meet product development goals set by management team.

- Provide support functions to the R&D team such as ordering and maintaining reagents/supplies/equipment, maintaining accurate notes and records, and effective communication with other DiscoverX departments.

- Demonstrates and promotes the company vision

- Regular attendance and punctuality

- Applies ISO quality standards in all areas of responsibility, as appropriate

- Conducts all activities in a safe and efficient manner

- Performs other duties as assigned

- Owns the accountability and responsibility of delivering to client needs and timeliness

- Provides cross-functional support to other departments as required

- Adheres to site environmental health and safety (EHS) requirements

**Qualifications**

**The ideal candidate:**

- B.S., M.S. or Ph.D. in cell biology, biochemistry, immunology or related discipline, with a minimum of 3 years of industrial experience.

- Supervisory experience desirable, but not required

- Extensive mammalian cell culture experience with both adherent and suspension cells and demonstrated expertise in developing or running cell-based assays required.

- Experience performing flow cytometry, TR-FRET, transcriptional reporter assays, ELISA, or similar assays, preferably in 96-well and 384-well plate formats strongly preferred

- Knowledgeable in GPCR pharmacology and relevant assay readouts, and experience studying diverse cell signaling pathways desirable

- Familiar with assembling and plotting data in GraphPad Prism, SoftMax Pro, MicroSoft Excel or Powerpoint and presenting data to supervisor and peers

- Demonstrated success in independently performing advanced troubleshooting and contributes additional tactical skills

- Demonstrated ability to work efficiently and productively in a fast-paced highly collaborative team environment

- Highly motivated, detail-oriented individual with excellent problem-solving, organizational and multi-tasking skills

**Additional Information**

**Salary Range: $120,000 - $145,000/yr.**

The position is full-time, Monday-Friday, 8 a.m.- 5 p.m., with overtime as needed.

- Excellent full time benefits including comprehensive medical coverage, dental, and vision options

- Life and disability insurance

- 401(k) with company match

- Paid vacation and holidays

**Eurofins USA Discovery Services is a Disabled and Veteran Equal Employment Opportunity employer.**

Senior Scientist

We are Sanofi, an innovative global healthcare company. We chase the miracles of science to improve people’s lives. 

Our team, across some 100 countries, is dedicated to transforming the practice of medicine by working to turn the impossible into the possible. We provide potentially life-changing treatment options and life-saving vaccine protection to millions of people globally, while putting sustainability and social responsibility at the center of our ambitions.

Interactions with this account must comply with the Terms: https://bit.ly/sanofi-terms

Industry: Fabrication de produits pharmaceutiques
Company Size: + de 10 000 employés

Sanofi

**Job title **:~~Senior Scientist Automation and Advanced Modeling~~

- Location: Cambridge, MA

**About The Job**

We are seeking highly motivated individual to join our drug substance process engineering and modeling team. As a technical expert in process engineering and modeling, you will play a key role in advancing our global engineering department within Sanofi’s R&D CMC Synthetic organization. This position is located in Cambridge MA and will collaborate closely with colleagues in France to support digital development and implement new ways of working.

Your expertise in chemical engineering, process system modeling, and lab automation will be crucial in creating a self-driving lab for small molecule drug substance process development and optimization. You will help developing automated experimental workflows to generate data for model building, advancing the creation of digital twins and driving innovation in pharmaceutical process development.

We believe that lab automation and digital development are crucial for the future of process development in Pharma. By joining our team, you will be at the forefront of this transformation, using your expertise to push the boundaries of process engineering.

This is an exciting opportunity to demonstrate the benefits of process modelling and data science in a cutting-edge scientific department developing the next generation of Sanofi medicines that will improve the quality of life for patients across the world.

Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions.

**About Sanofi**

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

**Main Responsibilities**

Lab automation & data generation:

-  You will work closely with laboratory teams (process chemists, engineers, and the high-throughput experimentation team), fostering strong partnerships with scientists to deeply understand their research processes. Your goal will be to design, develop, and deploy cutting-edge automated systems, robotics, instrumentation, and digital workflows that significantly enhance the productivity and efficiency of our labs.

- You will be responsible for programming and developing automated laboratory systems. This includes supporting software development and deployment to automate workflows, integrating analytical instruments with laboratory software, and ensuring seamless communication between instruments and Sanofi's internal data management services.

- Mechanistic & data-driven model building - As part of matrix project teams, build mechanistic, hybrid, and data-driven modeling solutions to support small molecule process development. Collaborate with process development teams to integrate crystallization modeling into the overall process design and optimization workflow.

- Model deployment at scale – Assist in the development and deployment of digital twins for both batch and continuous processes, ensuring alignment with Quality by Design (QbD) principles. You will play a key role in implementing and scaling Model Predictive Control (MPC) systems, leveraging advanced process models to optimize performance in real-time, maintain product quality, and enhance operational efficiency across large-scale manufacturing environments.

- Provide concise technical presentations to communicate work to project teams, cross functional teams and management.  Document all work on projects and continuous improvements in eLNB experiments and summarize in Technical Reports.

- Establish/extend external network by providing leadership on academic, industrial, or government sponsored collaborations.  Steer collaboration projects to address gaps in scientific knowledge.

**About You**

- PhD or PhD candidate in chemical engineering, mathematics, physics or related with expected graduation date by first semester of 2027 with 0+ years of experience academic experience will be considered) OR a master's degree in chemical engineering, mathematics, or physics or related with a minimum of 4 years of experience (academic experience will be considered) OR a bachelor's degree in chemical engineering, mathematics, or physics with a minimum of 8 years of experience.

- Strong skills in writing and optimizing scripts in programming languages such as Python/Matlab/C#/Visual Basic.

- Experience with crystallization modeling and/or simulation tools (e.g., gPROMS).

- Experience in designing and implementing automated laboratory processes from the initial concept through to full deployment.

- Demonstrated ability to translate mathematical models into computer programs.

- An ability to work as part of a team, engaging other scientists with complementary skill sets in the field of pharmaceutical development.

- A change agent mentality, proposing novel approach to challenging scientific questions and exploring new modeling approaches.

**Preferred Qualifications**

- Familiarity with laboratory analytical measurement instruments or relevant work experience in a pharmaceutical sciences laboratory setting.

- Domain knowledge in small molecule process development with demonstrated industrial applications or academic publications in this field.

- Some knowledge in Multivariate Analysis, chemometrics and statistics.

- Experience in the development and scale-up of continuous processes.

**Why Choose Us**

- Bring the miracles of science to life alongside a supportive, future-focused team.

- Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

- Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

- Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

- Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.

- Help improve the lives of millions of people globally by making drug development quicker and more effective.

- Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

#GD-SA

#vhd

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

Senior Scientist Automation and Advanced Modeling

At Merck, known as MSD outside of the United States and Canada, we are unified around our purpose: We use the power of leading-edge science to save and improve lives around the world. For more than 130 years, we have brought hope to humanity through the development of important medicines and vaccines. We aspire to be the premier research-intensive biopharmaceutical company in the world – and today, we are at the forefront of research to deliver innovative health solutions that advance the prevention and treatment of diseases in people and animals. We foster a diverse and inclusive global workforce and operate responsibly every day to enable a safe, sustainable and healthy future for all people and communities. For more information, visit www.merck.com. 

This site is intended for residents of the United States and Canada and their territories only. FLS: http://merck.us/3TKXNuZ

Industry: Pharmaceutical Manufacturing
Company Size: 10,001+ employees

Merck

**Job Description**

The Cardiometabolic Disease (CMD) department at our company's Research Labs in South San Francisco is seeking a Senior Scientist to join our discovery team. This role offers an exciting opportunity to contribute to cardiovascular drug discovery by developing and applying robust cell-based and ex-vivo systems to advance understanding of disease biology and mechanism of action.

The successful candidate will demonstrate strong initiative, operating in a multidisciplinary, matrixed environment to identify, mechanistically validate, and advance novel therapeutic targets for cardiovascular disease. This role is well suited for an intellectually curious and driven scientist with a hypothesis-focused mindset who excels at integrating in vitro findings with preclinical in vivo and human-relevant insights to inform discovery-stage decisions.

**Key Responsibilities**

- Independently design, optimize, and execute cell-based and ex-vivo assays to interrogate disease pathways and pharmacologic mechanisms.

- Lead mechanism-of-action studies using molecular, biochemical, and cellular approaches to link target modulation to disease biology.

- Generate high-quality, reproducible data and apply critical analysis to guide decision-making and prioritization.

- Collaborate effectively with cross-functional teams to advance cardiovascular drug discovery programs.

- Incorporate emerging assay technologies to strengthen discovery capabilities.

- Stay current with scientific advances in cardiovascular and translational biology.

- Communicate scientific rationale, assay strategies, and key findings clearly to diverse audiences.

- Maintain rigorous documentation in electronic lab notebooks and contribute to presentations, technical reports, and manuscripts.

**Education**

**QUALIFICATIONS:**

- Master's (with 4+ years) or Ph.D. (with 1+ years) in physiology, pharmacology, biomedical sciences or related field and relevant drug discovery experience.

**Required Experience And Skills**

- Demonstrated expertise in designing, executing, and interpreting in vitro and ex-vivo experiments with high scientific rigor.

- Proven ability to independently drive experiments, troubleshoot assays, and derive actionable conclusions.

- Demonstrated creativity and problem-solving ability in addressing complex biological questions using state-of-the-art in vitro approaches (reflected by publications and/or impactful internal contributions).

- Proficiency in standard molecular, cellular, and biochemical techniques.

- Strong quantitative skills, including data analysis and application of statistical approaches to biological datasets.

- Excellent communication and organizational skills, with the ability to manage multiple projects in a matrixed environment.

**Preferred Experience And Skills**

- Experience with primary or advanced cell culture systems (including 2D and 3D models) in cardiac or vascular biology.

- Strategic thinker with a background in one or more relevant areas (atherosclerosis, heart failure, inflammation, renal disease, lipid metabolism).

- Solid understanding of the translational strengths and limitations of in vitro models.

- Experience developing fit-for-purpose in vitro assays to support compound profiling and mechanism-based evaluation.

- Familiarity with multi-omics approaches (e.g., single-cell RNA-seq and proteomics) to support target biology and validation.

- Understanding of in vivo cardiovascular models and physiological endpoints.

#EligibleforERP

**Required Skills**

Cardiometabolic, Cell Cultures, Ex Vivo Assays, In Vitro Assays, In Vitro Models, In Vitro Studies, Vascular Biology

**Preferred Skills**

Current Employees apply HERE

Current Contingent Workers apply HERE

**US And Puerto Rico Residents Only**

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

**Requirements**

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

The salary range for this role is

$131,400.00 - $206,800.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

**San Francisco Residents Only: ** We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

**Los Angeles Residents Only: ** We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

**Search Firm Representatives Please Read Carefully**

Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

**Employee Status**

Regular

**Relocation:**

Domestic/International

**VISA Sponsorship**

Yes

**Travel Requirements**

No Travel Required

**Flexible Work Arrangements**

Not Applicable

**Shift**

1st - Day

**Valid Driving License**

No

**Hazardous Material(s)**

N/A

**Job Posting End Date**

06/2/2026

- A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

**Requisition ID: **R398471

Senior Scientist, In Vitro (Cardiometabolic Disease)

AbbVie is a global biopharmaceutical company focused on creating medicines and solutions that put impact first — for patients, communities, and our world. We aim to address complex health issues and enhance people's lives through our core therapeutic areas: immunology, oncology, neuroscience, eye care, aesthetics and other areas of unmet need.  

Learn more about us at www.abbvie.com and review our community guidelines at https://www.abbvie.com/social-media-community-guidelines.html.

Industry: Pharmaceutical Manufacturing
Company Size: 10,001+ employees

AbbVie

**Company Description**

**About AbbVie**

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.

**Job Description**

We are looking for an experienced and versatile Senior Scientist II/Mechanical Engineer to join our Injection Device Development team to help us accelerate AbbVie’s combination products from proof-of-concept through submission, industrialization and launch.

Our team has end-to-end accountability for commercial development, submission, industrialization and marketed product support for injection devices that enable the delivery of AbbVie’s innovative medicines. In the course of our work, we collaborate with early-stage CMC, Quality Assurance, Regulatory Affairs, Internal and External Manufacturing, and other cross-functional colleagues to ensure timeliness, robustness and market success.

As a Principal Research Scientist I at AbbVie you will be part of a multi-disciplinary team of professionals working at the intersection of engineering and biopharmaceuticals. The problems you would help to solve relate not only to the function of innovative injection systems, but also the way in which they interact with drug products and the human body. You would be responsible for advancing programs that combine proven delivery systems with viable commercial drug assets. If you are a self-motivated person who thrives on solving complex problems and are excited by the idea of putting life-changing therapies in the hands of patients, this might be the opportunity for you.

**Responsibilities**

- Create and maintain product design documentation

- Lead design transfer and industrialization activities

- Initiate and lead product design changes and continuous improvement effort

- Design and execute laboratory studies supporting product development and on-market investigations

- Conduct analytical modeling of key performance attributes of designs

- Perform 3D and 2D CAD development in PDM environment

- Protocol development, documentation of results and authoring of summary reports

- Collaborating with third party developers and suppliers

- Mentor/supervise a team of one or more and evaluate the performance of those individuals; is accountable for the effective performance of the team/individuals

**Qualifications**

- BS in Mechanical or Biomedical Engineering (MS preferred, PhD aspirational)

- 14+ years of experience (MS 12+ years, PhD 6+ years) ideally in the medical device, drug delivery or other regulated industry

- Demonstrated ability to function as a principle investigator, generating original technical ideas and research or development strategies.

- Demonstrate creative 'out of the box' thinking to solve difficult technical problems and champion new technologies to achieve project goals

- Experience with: Design controls (in accordance with ISO 13485 / CFR 820.30), high volume manufacturing processes, 3D CAD modeling, detailed engineering drawings, product database management environment and GD&T, laboratory environment, experiment planning, material control and recordkeeping, technical protocol and report writing, statistical analysis, physical prototyping (including 3D printing, manual machining, etc.), toolroom environment

- Knowledge of material properties, material selection and testing methodologies

- The ability to create and manage schedules for sub-tasks and work streams

-  A keen eye for identifying project risks and proactively developing mitigation plans

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

- The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of thisposting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location,and we may ultimately pay more or less than the posted range. This range may be modified in the future.

- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.

- This job is eligible to participate in our long-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission,incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless anduntil paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

Senior Scientist II/Mechanical Engineer

Bruker Life Science Mass Spectrometry is a leading global developer and manufacturer of innovative scientific instruments that address the rapidly evolving needs of a diverse array of life sciences customers. Our mass spectrometry-based tools serve the pharmaceutical, biotechnology, molecular diagnostics research and chemical analysis industries. Bruker's analytical instruments deliver exceptional high-resolution results for pre-clinical and clinical testing.  Research institutes, universities and government agencies routinely turn to Bruker for systems that address real world needs.

Innovations such as Trapped Ion Mobility (TIMS), smartbeam and scanning lasers for MALDI-MS Imaging that deliver true pixel fidelity, and eXtreme Resolution FTMS (XR) technology capable to reveal Isotopic Fine Structure (IFS) signatures are pushing scientific exploration to new heights. Our mass spectrometry solutions enable scientists to make breakthrough discoveries and gain deeper insights.

Bruker's product lines include the following technologies: timsTOF, MRMS, rapifleX® MALDI-TOF/TOF, UHR-QTOF, Triple Quadrupole, HDX Solution, Toxtyper® and TargetScreener HR. Our industry leading software solutions such as SCiLS™ Lab for MS Imaging, MetaboScape® and Biopharma Compass® are examples for our solutions doing the work for you.

(For Research Use Only. Not for use in clinical diagnostic procedures)

Industry: Biotechnology Research
Company Size: 1,001-5,000 employees

Bruker Daltonics

Bruker is one of the world’s leading analytical instrumentation companies enabling scientist to make breakthrough discoveries and develop new application that improve the quality of human life. Our high-performance products and high-value life science and diagnostic solutions are trusted by leading businesses, institutes, and scientists worldwide. Today, more than 11,000 employees at over 90 locations are working on this permanent challenge to make the world a better place.

Bruker Spatial Genomics (BSG, a Bruker subsidiary) is focused on opening a new frontier in spatial 3D genomics and multiomic analyses. We are committed to the development of a novel technology platform allowing progress in genome-wide visualization of spatially resolved 3D chromosome and chromatin architecture in individual cells and cell populations in situ. We bring together the premier spatial omics approach, jebFISHTM, with leading-edge imaging, data acquisition and analysis capability.

Our pioneering in situ technology enables examination of some of the most important questions in genomics and gene expression at the single cell and sub-cellular level. We aim to find the best talent in the field to join and contribute to this extraordinary endeavor, becoming a critical member of this groundbreaking opportunity.

Bruker Spatial Genomics Is Looking For a Staff Scientist For Their R&D Team. The Position And Ideal Candidate Is Described As Follows

-  The candidate will be a key contributor to optimization and development of advanced bioassays for determination of chromosome and chromatin architecture through the use of spatial omics approaches.

-  This is a unique multi-disciplinary position that will work closely with a variety of disciplines including scientists and engineers with molecular biology, general wet lab, or imaging experience. As part of our team, you will design and conduct cutting edge approaches and experiments to map spatial gene activity and expression and develop new technologies for multiomic integration. You will conceptualize and oversee technique invention, optimization, and transfer of the leading approach to in situ imaging of gene activity, localization, and expression in diverse tissue (FF and FFPE) and cell types.

-  The ideal candidate should have demonstrated wet lab experience working independently in a biophysics, chemistry, biochemistry, or molecular biology laboratory, have exceptional attention to detail, be creative, and be able to critically analyze data and communicate results to the team. This position must be able to independently make decisions on work direction.

-  They should be enthusiastic to work as part of a team in a fast-paced startup environment, and must bring a can-do attitude and sense of purpose to the job.

**Responsibilities**

-  Support and spearhead the method development and optimization of novel molecular biology assay schemes for spatial omic applications including molecular barcoding, fluorophore marking, nucleic acid hybridization, amplification and sequencing techniques, and probe library preparation.

-  Support the optimization of probe chemistry and probe-based sequencing with spatial multi-omic profiling applications.

-  Help develop the optimization of sample preparation methods such as tissue/cell fixation and permeabilization in diverse tissue (FF and FFPE) and cell types.

-  Independently plan and execute experiments, accurately record details, provide in-depth analysis, and report results through documentation and presentations.

-  Assist/lead in the analysis of large and complex data sets, including developing routines for streamlined and automated data pipelines.

-  Prepare assay reagents and other components.

-  Work within multidisciplinary teams at all stages of product development.

-  Assist with research projects to profile spatial genomics. Collaborate with other team members on research studies.

-  Support and lead elements of the development, verification and validation of product related kits and reagents.

-  Analyze specimens on imaging instrumentation. Analyze research data and assist with data interpretation.

-  Interface directly with product development teams to transfer and optimize new technologies.

-  Prepare research reports and share findings with the team. Write protocols, develop procedures, and maintain accurate records.

-  Clearly communicate and present results; contribute data for making critical design decisions.

**Qualifications**

Educational/Experience requirements:

- PhD in biophysics, chemical/biomolecular engineering, molecular biology, biochemistry, cell biology, or a related field and 5+ years of hands-on molecular biology experience in an industrial setting.

- Proficient in standard molecular biology techniques such as sample preparation, nucleic acid amplification and purification (RNA/DNA), qPCR, and DNA sequencing or similar molecular biology techniques. Experience with applying microscopy to answer biological problems.

- Knowledge of advanced fluorescence in situ hybridization (FISH) or other in situ fluorescence probed-based techniques. Understanding of basic absorption and emission spectroscopy.

- Highly motivated with excellent attention to detail. Good communication (oral and written) and collaboration skills.

- Experience in cell culture and tissue (FF and FFPE) preparation techniques.

- Experience in troubleshooting and optimization of molecular biology assays including reagent formulation and workflow optimization.

- Experience with experimental design and data analysis. Must be capable of performing complex multi-step experiments with detailed and diligent attention to technique and protocols with accurate record keeping.

- Desire to be part of a rapidly evolving organization, which requires real-time communication, flexibility, working well with others, and a willingness to learn new techniques and methods.

**Additional Desirable Skills**

- Experience with multiplexed, multiomic imaging technologies in tissues and cells.

- Experience in product development including product release.

- Familiarity with basic statistical data and error analysis. Familiarity with single cell and/or spatial transcriptomics, fixation chemistry, Design of Experiments (DOE).

- Advanced fluorescence imaging techniques. Experience in microscopy image analysis.

- Familiarity with different cell and tissue segmentation software and programs

- Experience with use and troubleshooting of automated equipment, preferably for imaging applications.

At Bruker, base salary is part of our total compensation. The estimated base salary range for this full-time position is between $99,450 and $177,000 provides an opportunity to progress as you grow and develop within a role. The base salary for the role will depend on a several job-related factors, including, but not limited to education, training, experience, the geographic location of the successful candidate, skills, competencies, job-related knowledge and travel requirements for this position. Full-time employees may also be eligible for a performance-related incentive in addition to a full range of benefits including 401(k) with company match, an employee stock purchase plan, medical and dental plans, life insurance, short-term and long-term disability insurance, employee assistance program and paid time off including vacation, sick time and holidays, and more.

Bruker is an equal-opportunity employer. We evaluate qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, and

other legally protected characteristics.

Certain positions at Bruker require compliance with export control laws and as a result, all interviewed candidates for all positions will be screened pre-interview to determine their eligibility in light of export control restrictions

We are building reversible cryopreservation technology to solve the organ procurement and matching problem.

Cryopreservation is already essential to modern medicine — powering IVF and life-saving stem cell therapies. 

Now, we’re extending this technology to whole human organs — transforming hours of viability into weeks, or months, however long is necessary — so that no donated organ is lost to logistics, and no patient dies waiting. 

By solving this immediate need, we de-risk and build the foundation for what comes next: whole-body reversible cryopreservation. We're pausing molecular motion to give patients a bridge to future cures.

Industry: Biotechnology Research
Company Size: 11-50 employees

Until

Until is a moonshot company building a “pause button” for biology. Our near-term focus is organ-scale reversible cryopreservation: preserving donated organs at subzero temperatures without ice formation, then rewarming them uniformly for transplant. By solving this grand challenge, we’re laying the foundation for whole-body reversible cryopreservation, giving patients a bridge to future cures.

To achieve our goal, we are assembling an interdisciplinary team to develop perfusion systems, cryoprotectant formulations, and vitrification and rewarming hardware.

We envision a future where no transplantable organ is lost to logistics, and no terminal diagnosis is final because patients can safely wait for future medicine to arrive.

**About The Role**

We are seeking a Senior Scientist to join as a leader on our whole organ preservation team. You will have large domain of ownership and play a vital role in shaping the company's organ transplant research program. You will apply your expertise in organ perfusion, preservation, viability assessment, and transplant to make successful large organ cryopreservation a reality.

You will have the opportunity to collaborate with scientists and engineers across the company on variety of methods inspired by first principles of biology, physics, and chemistry. Creative scientific engagement is a requirement of the role, and new avenues for discovery and optimization are continuously supported.

**Responsibilities**

- Implement pig organ ex-vivo viability evaluation protocols, including perfusion, histology, omics, etc

- Ability to comfortably execute familiar assay protocols as well as identifying and implementing unfamiliar protocols to diagnose damage

- Propose adjustments to cryopreservation protocol to optimize the health of organs

- Experience working with ex vivo kidney and / or heart perfusion and viability assessment is a plus

**Qualifications**

- You’ve completed a PhD in STEM, ideally in the field of organ preservation or transplant, or otherwise have significant (4+ years) experience working as a scientific leader in an industry context.

- You have demonstrated a passion for rapid problem solving and exploration of novel topics / protocols, demonstrated success working through hard problems

- Desire to work in a laboratory setting to apply your expertise.

- You demonstrate agency, problem solving, passion for discovery, and a drive to push the boundaries of science through meaningful involvement in an ambitious project

**Benefits**

- A unique opportunity to learn new skills, develop impactful technology, and work with an ambitious team

- Medical and dental insurance coverage

- Flexible time off and paid holidays

- Competitive compensation package, including salary and equity

- Access to a 401(k) retirement savings plan

As an equal opportunity employer, Until is committed to providing employment opportunities to all individuals. All applicants for positions at Until will be treated without regard to race, color, ethnicity, religion, sex, gender, gender identity and expression, sexual orientation, national origin, disability, age, marital status, veteran status, pregnancy, or any other basis prohibited by applicable law.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

While this represents our expected range based on market data, final compensation will be determined based on your specific qualifications and may be outside this range. Please keep in mind that the equity portion of the offer is not included in this estimate.

Senior Scientist (Organ Perfusion)

BioSpace is the digital hub for life science news and jobs. We provide essential insights, opportunities and tools to connect innovative organizations and talented professionals who advance health and quality of life across the globe.

Industry: Internet News
Company Size: 11-50 employees

BioSpace

**Job Title **: Senior Principal Scientist, Lab Head Medicinal Chemistry

**Location: ** Cambridge, MA

Do you thrive on solving drug discovery challenges and driving therapeutic programs forward with speed and efficiency? Your skills could be critical in helping our teams accelerate progress.

Integrated Drug Discovery (IDD) is the small molecule drug discovery platform within Sanofi. IDD is an international, interdisciplinary group that spans medicinal chemistry, structural biology, screening, biochemistry, biophysics, cellular pharmacology, delivery technologies, sample management and more.

Our vision is to deliver valuable, high quality synthetic drugs of varying modalities to improve the lives of patients. Our mission is to provide innovation and key enabling technologies to drive the discovery of synthetic small molecules and emerging synthetic modalities as drug candidates in the Sanofi Research Portfolio; to deliver high quality science and innovative approaches to drug discovery, and to perform as a highly collaborative flexible and forward-looking organization with broad impact across the Sanofi pipeline. We are seeking a dynamic and experienced medicinal chemist to join our Cambridge, MA-based team as a Senior Principal Scientist.

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve peoples lives. Were also a company where you can flourish and grow your career, with many opportunities to explore, connect with people, and stretch the limits of what you thought was possible. Ready to get started?

**Main Responsibilities**

- The ideal candidate is an experienced leader who excels at solving complex challenges with innovative approaches, brings critical thinking and strategic vision, and consistently delivers results under pressure.

- A Senior Principal Scientist is responsible for applying deep scientific expertise and judgment to initiate, design, and direct medicinal chemistry in support of research goals.

- Is an expert in analyzing, interpreting and communicating scientific content to teams and stakeholders.

- Demonstrates continuous growth in depth and breadth of scientific knowledge and understanding of strategic goals of group, team and company.

- Successfully works as an impactful contributor, and as a leader of project teams and transverse initiatives; is an experienced and supportive manager and mentor of other medicinal chemists.

- Has an established and growing reputation in the external scientific community through high impact publications, productive scientific collaborations and active participation in conferences.

**Qualifications**

**About You**

- Demonstrated success leading multidisciplinary drug discovery projects from conception through key milestones.

- Experience in all phases of the small molecule discovery process from hit ID to candidate nomination.

- Exceptional technical skills and demonstrated ability to work and thrive in a collaborative cross-functional team setting; proven ability to analyze complex data sets, draw conclusions, and design follow-on experiments.

- Experience working with CROs and external collaborators.

- Comfortable and efficient in fast moving complex global environment.

- Demonstrated track record of intellectual contributions in drug discovery as evidenced by impactful peer-reviewed publications, presentations, patents, and project achievements.

- Proven track record mentoring and developing junior scientists with measurable impact on team performance and individual career growth.

- PhD in Organic/Medicinal Chemistry with 7+ years of experience in a pharmaceutical/biopharmaceutical environment.

- Or Masters degree in Organic Chemistry with 9+ years of experience in a pharmaceutical/biopharmaceutical environment.

- Or Bachelors degree with 12+ years of experience in a pharmaceutical/biopharmaceutical environment.

**Why Choose Us?**

- Bring the miracles of science to life alongside a supportive, future-focused team.

- Discover endless opportunities to grow your talent and drive your career, whether its through a promotion or lateral move, at home or internationally.

- Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

- Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

#GD-SA

#vhd

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

Senior Principal Scientist, Lab Head Medicinal Chemistry

**Job Description**

Under the guidance of a senior leader, the Principal Scientist (Director), Outcomes Research—Women’s Cancer will be a leader in the team responsible for a tumor-level evidence strategy and plan. Will develop and maintain tumor and indication expertise. Will assess unmet medical need and value across tumors/indications for the asset for asset-level tumor/indication prioritization discussions.

Types of studies executed include prospective and retrospective observational studies to characterize disease burden and epidemiology, treatment patterns, healthcare resource utilization and costs, physician and patient satisfaction surveys, clinical and patient reported outcomes assessments, and systematic reviews and meta-analyses. Incumbent is expected to contribute to product development and marketing strategies throughout the lifecycle to ensure that product value is defined and developed to achieve optimal market/patient access and reimbursement. The incumbent is expected to work cross-functionally with clinical development, medical affairs, biostatistics, market access, commercial and country affiliates and may have direct interactions with health technology assessment (HTA) agencies and reimbursement decision makers especially related to drug launches.

**Primary Responsibilities**

- Lead in value evidence teams in Women’s Cancer and contribute to value evidence strategies. Obtain senior management approval of evidence generation plans. Provide outcomes research leadership on cross-functional regional and global teams.

- Critically assess drivers and barriers to reimbursement and market access, and provide input into clinical, regulatory, payer/access, marketing and evidence generation strategies and programs.

- In collaboration with internal teams and external partners, design studies, author study protocols, develop measurement questionnaires, case report forms, data analysis plans, final study reports, scientific presentations, and publications.

- Responsible for study-related contracting, and budgets.

- Develop supplementary clinical data package in close partnership with markets and HTA statistics group for submission to HTA agencies.

- Support country affiliates to understand local evidence generation needs, adapt health economic evaluations, customize outcomes research documents, such as protocols and reimbursement dossiers, according to local requirements.

- Work closely with cross functional teams to effectively communicate outcomes research and health economic modelling data internally and to external stakeholders.

- Maintain awareness of new scientific and methodological developments within therapeutic area.

- Build relationships with scientific experts worldwide.

- Present outcomes research data at national and international congresses and publish articles in scientific journals.

**Qualifications**

**Preferred:**

- Doctoral degree (PhD, DrPH, ScD, PharmD) in relevant discipline (health services research, outcomes research, epidemiology, public health, health economics, Pharmacoeconomics, pharmacy administration).

**Required**

- Master’s degree (MSc, MPH) in relevant discipline (health services research, outcomes research, epidemiology, public health, health economics, Pharmacoeconomics, pharmacy administration).

**Experience**

- 4+ years of experience post degree

**Required Skills**

Biostatistics, Clinical Development, Clinical Outcomes, Collaborative Development, Communication, Data Management, Epidemiology, Health Economics, Health Technology Assessment (HTA), Market Access, Marketing Strategies, Neuroanatomy, Outcomes Research, Pathophysiology, Researching, Stakeholder Relationship Management, Strategic Planning

**Preferred Skills**

Current Employees apply HERE

Current Contingent Workers apply HERE

**US And Puerto Rico Residents Only**

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

**Requirements**

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

The salary range for this role is

$190,800.00 - $300,300.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

**San Francisco Residents Only: ** We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

**Los Angeles Residents Only: ** We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

**Search Firm Representatives Please Read Carefully**

Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

**Employee Status**

Regular

**Relocation:**

Domestic

**VISA Sponsorship**

No

**Travel Requirements**

10%

**Flexible Work Arrangements**

Hybrid

**Shift**

Not Indicated

**Valid Driving License**

No

**Hazardous Material(s)**

n/a

**Job Posting End Date**

06/10/2026

- A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

**Requisition ID: **R399875

Principal Scientist (Director) -Outcomes Research

**Job Description**

We are seeking an accomplished and highly motivated Senior Principal Scientist (Sr. Director equivalent) to serve as an Immunology Biomarker Lead within Translational Clinical Biomarkers. This role provides strategic and scientific leadership in the design, execution, analysis, and communication of clinical biomarker strategies across our immune-mediated therapeutic portfolio from discovery to pivotal clinical studies.

The successful candidate will drive decision-centric biomarker strategies that connect drug mechanism, disease biology, precision medicine, pharmacodynamics, dose decisions, and clinical endpoints, directly informing program- and portfolio-level decisions across the development lifecycle.

This role requires strong leadership of multi-disciplinary team efforts through deep scientific expertise, structured decision-making, sophisticated data analysis & interpretation; and cross-functional collaboration, aligning stakeholders in a fast-paced, matrixed environment.

**Primary Responsibilities**

**Strategic Leadership & Program Impact:**

- Lead and shape integrated biomarker strategies across discovery, early- and late-stage clinical programs, ensuring clear hypotheses, fit-for-purpose endpoints, and explicit linkage to key development decisions, in close collaboration with cross-functional leaders, particularly in Discovery, Late-Stage Clinical Development and across Translational Medicine

- Serve as the biomarker strategy lead within cross-functional program teams and represent multi-disciplinary team(s) in governance forums, ensuring biomarker strategies to address mission-critical questions for both forward and reverse translation

- Inform portfolio strategy by advancing biomarker-driven insights that inform target validation, patient selection, and go/no-go decisions

- Translate disease biology and therapeutic mechanism of action into clinically actionable biomarker strategies addressing critical program questions, e.g. proof of biology, pharmacodynamic effects, precision medicine and surrogate endpoints for efficacy.

- Drive selection and application of innovative biomarker approaches, aligned with biological rationale and clinical utility

**Cross-functional Leadership & Alignment**

- Lead biomarker sub-teams and related working groups, including clinical, discovery, translational, regulatory, bio-stats, and data sciences

- Collaborate effectively across disciplines to integrate scientific perspectives into cohesive strategies

- Provide scientific leadership to enable hypothesis-driven, decision-focused biomarker strategies

- Grow and develop team members, including mentorship of direct report(s) and other scientists in the department, acting as a role model and culture driver

**Data Interpretation & Communication**

- Champion biomarker analysis plans and provide critical scientific input to the interpretation of complex datasets to deliver scientifically rigorous and clinically meaningful conclusions

- Clearly articulate insights to internal stakeholders, governance bodies, and external scientific audiences

- Support external engagement, including publications, presentations, and KOL interactions, as appropriate

**NOTE: This role is available in Rahway, NJ, Boston/Cambridge, MA or Upper Gwynedd, PA based on candidate preference**

**Education**

**QUALIFICATIONS:**

- Ph.D. or M.D. with 12+ years in Immunology or related scientific discipline and relevant experience with autoimmune diseases and/or translational medicine

**Required Experience And Skills**

- Deep expertise in immunology and immune-mediated/inflammatory diseases, with experience in at least one of the following:

- Gastrointestinal/mucosal inflammation

- Rheumatology

- Dermatology

- Proven track record of driving translational strategies that inform clinical development decisions, including close cross-functional collaboration and partnership

- Demonstrated ability to lead highly matrixed organizations

- Strong analytical and problem-solving capabilities, with the ability to translate complex data into clear, decision-oriented insights

- Excellent communication skills, including experience presenting to senior leadership and external stakeholders

- Working knowledge with biostatistics, bioinformatics, and advanced data analytics

- Strategic mindset with a focus on decision impact rather than data generation alone

- Strong leadership presence and ability to influence cross-functional and senior stakeholders

- Proven ability to operate effectively in a fast-moving, matrixed environment

**Preferred Experience And Skills**

- Experience advancing precision medicine strategies

- Direct managerial experience

#EligibleforERP

**Required Skills**

Autoimmune Diseases, Biomarker Research, Dermatology, Gastrointestinal Disease, Immunology, Inflammatory Diseases, Leadership, Rheumatology, Strategic Planning, Translational Medicine

**Preferred Skills**

Current Employees apply HERE

Current Contingent Workers apply HERE

**US And Puerto Rico Residents Only**

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

**Requirements**

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

The salary range for this role is

$210,400.00 - $331,100.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

**San Francisco Residents Only: ** We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

**Los Angeles Residents Only: ** We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

**Search Firm Representatives Please Read Carefully**

Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

**Employee Status**

Regular

**Relocation:**

Domestic/International

**VISA Sponsorship**

Yes

**Travel Requirements**

10%

**Flexible Work Arrangements**

Hybrid

**Shift**

1st - Day

**Valid Driving License**

No

**Hazardous Material(s)**

N/A

**Job Posting End Date**

06/30/2026

- A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

**Requisition ID: **R399013

Senior Principal Scientist, Translational Clinical Biomarkers

In an era of accelerating change, Exponent is the only premium engineering and scientific consulting firm with the depth and breadth of expertise to solve our clients’ most profoundly unique, unprecedented, and urgent challenges.

Exponent brings together 90+ technical disciplines and 950+ consultants to help our clients navigate the increasing complexity of more than a dozen industries, connecting decades of pioneering work in failure analysis to develop solutions for a safer, healthier, sustainable world.  

Our consultants deliver the highest value by leveraging multidisciplinary expertise and resources from across Exponent's offices in North America, Asia, and Europe. Exponent's consultants, laboratories, databases, and computing resources work seamlessly together around the globe, enabling us to produce the breakthrough insights needed to help multinational companies, startups, law firms, insurance companies, government, and society respond to incidents and push their products and processes forward. 

Exponent is certified to ISO 9001.

Industry: Business Consulting and Services
Company Size: 1,001-5,000 employees

Exponent

**About Exponent**

**Exponent ** is the only premium engineering and scientific consulting firm with the depth and breadth of expertise to solve our clients’ most profoundly unique, unprecedented, and urgent challenges.

Our vision is to engage multidisciplinary teams of science, engineering, and regulatory experts to empower clients with solutions that create a safer, healthier, more sustainable world. For over five decades, we've connected the lessons of past failures with tomorrow's solutions to advise clients as they innovate technologically complex products and processes, ensure the safety and health of their users, and address the challenges of sustainability.

Join our team of experts with degrees from top programs at over 500 universities and extensive experience spanning a variety of industries. At Exponent, you’ll contribute to the diverse pool of ideas, talents, backgrounds, and experiences that drives our collaborative teamwork and breakthrough insights. Plus, we help you grow your career through mentoring, sponsorship, and a culture of learning. Thanks for your interest in joining our team!

**Key statistics:**

-  950+ Consultants

-  640+ Ph.D.s

-  90+ Disciplines

-  30+ Offices globally

**Our Opportunity**

We are seeking an experienced consultant for a **Principal Scientist ** position in our  **Polymers & Chemistry ** Practice . This position is open across all U.S. office locations . In this role you will lead in terdisciplinary project team s that investigate and solve complex problems related to the specification , development, testing , and end-use performance of polymeric materials used in life sciences , consumer products, building and construction applications , infrastructure systems, and automotive components . C andidate s must also possess excellent written and verbal communication skills and the ability to convey scientific concepts in a credible manner to diverse audiences. This position requires some travel and will involve collaborating with scientists and engineers from other Exponent offices and practices . The successful candidate will have at least 10 years of scientific or engineering consulting experience with an established book of business . T he ideal candidate will cultivate relationships with existing clients, identify new business opportunities, and contribute to the continued growth of the Polymers & Chemistry Practice.

**You will be responsible for**

-  Leverag ing deep knowledge in polymer science to address a wide range of complex challenges across diverse client sectors , delivering scientifically rigorous and impactful solutions.

-  Identify ing , pursu ing , and secur ing new client engagements by understanding emerging needs and building long-term partnerships.

-  Maintain ing and grow ing trusted relationships with existing clients by consistently delivering high-quality work, anticipating future needs, and serving as a strategic advisor.

-  Build ing , manag ing , and empower ing multidisciplinary teams, fostering a collaborative and inclusive environment that values diverse perspectives and scientific integrity.

-  Provid ing guidance, coaching, and professional development opportunities to technical staff, supporting their growth into future leaders and experts.

-  Ensur ing successful project execution through effective planning, resource allocation, and budget management, while maintaining high standards of quality and timeliness.

-  Offer high-level scientific and strategic advice to both internal stakeholders and external clients, contributing to the firm’s thought leadership and client impact.

-  Enhance the firm’s visibility and credibility by publishing in peer-reviewed journals, presenting at industry conferences, leading seminars, and participating in expert advisory or technical committees.

-  Inspecting, testing and analyzing various polymeric materials to assess their specifications and/or reliability in a variety of applications from a wide range of industries

-  Performing root cause investigations on failing or underperforming materials/components by scientifically examining the development, manufacturing or end-use environment of products specified for use in the construction, medical device, consumer electronics, and automotive industries .

-  Analyzing information and conveying technical conclusions to individuals in engineering, business, law, and industry, as well as communicating testing rationale in the context of product development, product defect claims, and intellectual property dispute s .

**You Will Have The Following Skills And Qualifications**

-  PhD in Polymer Science or Materials Science with a focus on polymer structure-property-end use performance relationships

-  Minimum of 10 years of consulting experience in the polymer science or materials science space

-  Proven track record of business generation and attracting new and repeat clients or funding

-  Exceptional verbal and written communication skills, with the ability to articulate complex ideas clearly and persuasively to diverse audiences

-  Strong analytical and problem-solving skills, with the ability to interpret data, identify trends, and make informed recommendations in your scientific field

-  Outstanding reputation among clients and the scientific community for integrity, responsiveness, and technical expertise

-  Adept people management abilities coupled with extensive experience in successfully overseeing and executing complex projects

-  Strong commitment to professional development

-  This is a revenue-generating role with substantial sales expectations. This position requires achieving annual sales in excess of $1 million. Candidates must demonstrate a proven track record of managing an active client portfolio that consistently generates at least $1 million in annual revenue within industrial sectors or law firms (excluding revenue derived from government funding for academic research projects)

Applicants are encouraged to submit a CV (Curriculum Vitae) with publications (feel free to include publications that are in review or pending) [not restricted to 1 page].

**Life @ Exponent**

To learn more about life at Exponent and our impact, please visit the following links:

https://www.exponent.com/careers/life-exponent

https://www.exponent.com/company/our-impact

We value and encourage diversity, equity and inclusion across all facets of our firm. Having a team built of people with different backgrounds, skills and perspectives allows us to provide better value to our clients and enjoy an enriched work environment.

Our firm is committed to offering a variety of programs and resources to support health and well-being. We believe that providing competitive benefits, as well as compensation and recognition programs, empowers our staff to do work that makes a difference.

**Work Environment**

At Exponent, we have found that in-person interactions deepen employee engagement and are crucial for development, for realizing the full potential of our talented and diverse teams, and for building a more inclusive workplace where all have a sense of belonging. In our offices, you can expect a supportive culture and a collaborative, dynamic, multi-disciplinary work environment. Our consultants engage in-person in the office unless they are traveling for client work or other business activities.

We value the rich lives our colleagues enjoy outside of work and understand that work/life balance is critical to our employees and their well-being. Consultants have the autonomy to balance their work and personal schedules so you can meet with clients, visit inspection sites, attend conferences, and make time for priorities outside of work, too. It is this flexible, agile work style and working hours that allow our teams to drive innovation and results in their own ways, while meeting the needs of clients.

**Compensation**

Our consultants are rewarded for their technical and business contributions and have an opportunity to plan for future success and career growth. Exponent's total compensation plan is consistent with its expectations of the quality and quantity of work performed and with the professional standards set by Exponent. At the Manager level and above, total compensation includes base salary, annual bonus, and 401(k) employer contribution of 7% of base salary.

The base salary range for this position is depending on experience and capabilities which will be assessed during the interview process.

**Salary Range**

USD $225,000.00 - USD $275,000.00 /Yr.

**Benefits You Will Enjoy**

Access benefits information on our Life @ Exponent page:

https://www.exponent.com/careers/life-exponent

Exponent is a proud equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, veteran status, disability, sexual orientation, gender identity, or any other protected status.

If you need assistance or accommodation due to a disability, you may email us at HR-Accommodations@exponent.com .

**Job Locations**

US-CA-Menlo Park

US-GA-Atlanta

US-TX-Austin

US-CA-Los Angeles

US-IL-Chicago

US-MD-Bowie

US-MA-Natick

US-AZ-Phoenix

US-CO-Denver

US-PA-Philadelphia

US-WA-Seattle...

Principal Scientist

**Job Description**

The Principal Scientist, Drug Discovery in our Research and Development Department will be responsible for identifying new molecular entities and technologies for use in animal health from our Company Laboratories or from external partners such as human pharma or biotech companies as well as academia. The successful candidate will be a key driver to advance novel targets and will lead these research programs from ideation through the early research and proof-of-concept phase up to the development stage. She/he/they will interface with researchers and senior management throughout the organization as well as external partners and operate within a matrix structure to garner resources for the necessary research work (Medicinal and Process Chemistry, in vitro Pharmacology, Pharmacokinetics, Disease Models, Formulation Development, Safety & Toxicology). The position will report directly to the Distinguished Scientist and Global Head, our Company's Research & Development Liaison and Discovery – Non-infectious Diseases.

**Education**

- Required: DVM/VMD, as well as a PhD in experimental pharmacology

**Required Experience**

- Minimum of 8 years industry or pharmaceutical research experience in drug discovery or preclinical research with a focus on in vivo pharmacology

- Advanced and thorough scientific knowledge in pharmacology, disease mechanisms and related preclinical models

- Expertise in one of the following fields: oncology, diabetes, respiratory & immunology, cardiology, pain & inflammation, reproduction, drug delivery or biotechnology

- Knowledge of regulatory aspects of pharmaceuticals including GLP, GCP and GMP

- Ability to manage multiple projects, including budgets, contracts, and timelines

- Ability to independently plan, recommend and complete research programs

- Excellent communication and interpersonal skills

- Effective creator of executive level presentations and documents

- Experience in preparing patent applications in support of patent coverage of research efforts

- 10 % Travel

**Preferred Experience**

- Board certification in Pharmacology

- Project management skills within pharmaceuticals

- Experience in developing and managing collaborations with outsource providers, vendors, contractors and academic institutions

- Experience in working with business development to identify and license external technology opportunities

**Location:**

- Our Company's Animal Health Headquarters, Rahway, NJ

**Required Skills**

Adaptability, Assay Development, Biochemical Assays, Cell Culture Techniques, Communication, Detail-Oriented, Ethical Compliance, Functional Genomics, In Vivo Models, Leading Project Teams, Molecular Biology Techniques, Persuasion, Professional Networking, Protein Biochemistry, Protein Purifications, Science, Social Collaboration, Virology

**Preferred Skills**

Current Employees apply HERE

Current Contingent Workers apply HERE

**US And Puerto Rico Residents Only**

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

**Requirements**

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

The salary range for this role is

$169,700.00 - $267,200.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

**San Francisco Residents Only: ** We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

**Los Angeles Residents Only: ** We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

**Search Firm Representatives Please Read Carefully**

Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

**Employee Status**

Regular

**Relocation:**

Domestic

**VISA Sponsorship**

No

**Travel Requirements**

10%

**Flexible Work Arrangements**

Hybrid

**Shift**

Not Indicated

**Valid Driving License**

No

**Hazardous Material(s)**

N/A

**Job Posting End Date**

06/5/2026

- A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

**Requisition ID: **R363749

Principal Scientist, Drug Discovery

**Job Description**

**Senior Principal Scientist (Senior Medical Director) Translational Medicine, Immunology**

Translational Medicine in our Research & Development Division is responsible for planning and managing an important inflection point in the drug development process, working closely with scientific, regulatory, statistical, and modeling colleagues across the organization to translate the benchtop science of preclinical discovery into compounds ready for assessment in large clinical populations.

We are seeking a highly qualified physician-scientist with a proven track record in both the pharmaceutical industry and independent academic research for a position in our group. Please note that our Senior Principal Scientist title is also equivalent to a Senior Medical Director position.

The preferred candidate will have at least 5 years of experience in the pharmaceutical industry, with a focus on Immunology R&D, as well as clinical and academic expertise in Immunology-related areas such as Dermatology, Rheumatology, or Gastroenterology.

For our efforts supporting the Immunology development pipeline, our closest collaborations are with groups based in Boston, MA; however, we will also be open to other locations, including West Point, PA, Upper Gwynned, PA, Rahway, NJ, and San Francisco, CA.

**Translational Medicine Is Specifically Responsible For**

- Contributing to the identification of novel targets by partnering with discovery research teams to bring a clinical insight into the earliest stages of target identification and validation, and executing clinical studies to evaluate the relevance of potential targets to human disease in order to justify investment in full development

- Development of biomarker strategies through cross-functional teams that provide line-of-sight from First-in-Human studies through clinical Proof-of-Concept. This includes Experimental Medicine studies to establish and/or validate novel clinical biomarker platforms.

- Development and execution of the early clinical development strategy for novel therapy/Immunology programs from Preclinical Candidate approval through clinical Proof-of-Concept (Phase 2a), and development and execution of clinical pharmacology strategies for late-stage development programs from Proof-of-Concept (Phase 2a) through worldwide marketing application.

Success depends on the integrity, knowledge, imagination, creativity, skill, diversity, and teamwork of the people in the group. To this end, we strive to create an environment of mutual respect, encouragement, and teamwork. As part of the global team, you will collaborate with talented and dedicated colleagues in Translational Medicine, as well as Discovery Sciences and late-stage Clinical Research while developing and expanding your career.

This role will report directly to the Immunology Therapeutic Area Lead in Translational Medicine.

**Primary responsibilities for the Senior Director (Senior Principal Scientist) include the following:**

- Key member of an early development team, providing leadership in designing and executing early clinical development strategy

- Development and execution of early clinical strategy for novel Immunology assets and therapeutics including authoring initial clinical and biomarker plans for Lead Optimization programs, early clinical development plans for Preclinical Candidate molecules, Phase 1a/b trials and and clinical pharmacology studies for programs in Phases I through IV of development.

- Development and execution of studies to validate clinical platforms utilizing established and novel biomarkers, including imaging, responses to interrogate biological activity in humans.

- Provide clinical expertise for identification and validation of novel targets, including the design of preclinical and/or clinical pharmacology experiments to validate targets and/or pathways

- Safe and timely execution of Phase I studies; close collaboration with internal and external clinical study support staff and scientists (including discovery research, biostatistics, drug metabolism, modeling and simulation, regulatory affairs, and global clinical trials operations)

- Provide clinical pharmacology support for programs through the worldwide marketing application filing including supportive registration documents and presentations

- Provide clear, timely communication and interpretation of study results to therapeutic area governance, functional area experts and development review committees.

- Contribute to assessment of internal and external opportunities identified by Business Development and Licensing

- Interface broadly with key functions including Discovery Sciences, Preclinical Pharmacology, Pharmaceutical Sciences, Toxicology, Translational Biomarkers, Translational Medicine Operations, Translational Medicine-EU, Drug Metabolism/Modeling & Simulation, Regulatory Affairs, and late-stage Clinical Research throughout sites in the USA, UK and Belgium.

**Position Qualifications**

**Education Minimum Requirement**

- MD or MD/PhD

- At least 5-year experience in the pharmaceutical industry in clinical research, preferrable in immunology clinical research, including translational research

- An educational/career track including both independently conceived and executed research and clinical patient care experience

**Required Experience And Skills**

- Proven track record in clinical research in the pharmaceutical industry

- Proven track record in clinical care of patient populations or management of clinical problem-solving, preferably in Dermatology

- Demonstrated record of scientific scholarship and achievement. Research expertise in any immunology field is preferred.

- Strong interpersonal, writing and presentation skills, as well as the ability to function in a team environment are essential.

- Board Certification or Eligibility (MD and MD/PhD) preferred

**Required Skills**

Academic Research, Clinical Studies, Clinical Trial Development, Dermatology, Drug Development, Gastroenterology, Immunology, Intellectual Curiosity, Pharmaceutical Research, Rheumatology, Scientific Publications, Scientific Research, Translational Research

**Preferred Skills**

Current Employees apply HERE

Current Contingent Workers apply HERE

**US And Puerto Rico Residents Only**

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

**Requirements**

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

**U.S. Hybrid Work Model**

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.

The salary range for this role is

$286,900.00 - $451,600.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

**San Francisco Residents Only: ** We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

**Los Angeles Residents Only: ** We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

**Search Firm Representatives Please Read Carefully**

Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

**Employee Status**

Regular

**Relocation:**

Domestic

**VISA Sponsorship**

No

**Travel Requirements**

10%

**Flexible Work Arrangements**

Hybrid

**Shift**

Not Indicated

**Valid Driving License**

No

**Hazardous Material(s)**

n/a

**Job Posting End Date**

05/7/2026

- A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

**Requisition ID: **R381994

Senior Director (Senior Principal Scientist), Translational Medicine, Immunology

**Job Description**

Under the guidance of a senior leader, an Associate Principal Scientist/Associate Director, has primary responsibility for planning/managing real world and economic evidence activities for in-line and pipeline products to meet the value evidence needs of clinicians, payers, policymakers, HTA/reimbursement agencies, and health systems globally.

Types of studies executed include prospective and retrospective observational studies to characterize disease burden and epidemiology, treatment patterns, healthcare resource utilization and costs, physician and patient satisfaction surveys, clinical and patient reported outcomes assessments, systematic reviews and meta-analyses, and economic modelling. Key responsibilities also include development of American Managed Care Pharmacy (AMCP) dossiers for US payers, and Global Value Dossiers for use by local subsidiaries in their HTA submissions. The incumbent is expected to work cross-functionally with clinical development, medical affairs, biostatistics, market access, commercial and country affiliates. The incumbent may supervise external vendors or partners to execute these activities. The incumbent may have direct interactions with health technology assessment (HTA) agencies, reimbursement decision makers, or national immunization technical advisory groups.

**Primary Responsibilities**

- Participate in value evidence teams and serves as outcomes research representative on cross-functional regional and global teams.

- Critically assess drivers and barriers to reimbursement and market access, and provide input into clinical, regulatory, payer/access, marketing and evidence generation strategy and programs.

- In collaboration with internal teams and external partners, design studies, author study protocols, develop measurement questionnaires, case report forms, data analysis plans, final study reports, scientific presentations, and publications.

- Responsible for study-related contracting, budgets, and vendor/partner management.

- Develop American Managed Care Pharmacy (AMCP) dossiers for US payers, and Global Value Dossiers

- Develop supplementary clinical data package in close partnership with markets and HTA statistics group for submission to HTA agencies.

- Support country affiliates to understand local evidence generation needs, adapt health economic evaluations, customize outcomes research documents, such as protocols and reimbursement dossiers, according to local requirements.

- Work closely with cross functional teams to effectively communicate outcomes research and health economic modelling data internally and to external customers.

- Maintain awareness of new scientific and methodological developments within therapeutic area.

- Build relationships with scientific experts worldwide.

- Present outcomes research data at national and international congresses and publish articles in scientific journals.

**Required Qualifications, Skills, & Experience**

**Minimum**

- Masters degree (MSc, MPH) in relevant discipline (health services research, outcomes research, epidemiology, public health, health economics, pharmacoeconomics, pharmacy administration)

- 1-3 years post degree

**Preferred**

- Doctoral degree (PhD, DrPH, ScD, PharmD) in relevant discipline (health services research, outcomes research, epidemiology, public health, health economics, pharmacoeconomics, pharmacy administration)

**Required Skills**

Data Management, Researching, Stakeholder Relationship Management, Strategic Planning

**Preferred Skills**

Current Employees apply HERE

Current Contingent Workers apply HERE

**US And Puerto Rico Residents Only**

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

**Requirements**

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

The salary range for this role is

$156,900.00 - $247,000.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

**San Francisco Residents Only: ** We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

**Los Angeles Residents Only: ** We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

**Search Firm Representatives Please Read Carefully**

Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

**Employee Status**

Regular

**Relocation:**

Domestic

**VISA Sponsorship**

No

**Travel Requirements**

10%

**Flexible Work Arrangements**

Not Applicable

**Shift**

Not Indicated

**Valid Driving License**

No

**Hazardous Material(s)**

n/a

**Job Posting End Date**

06/1/2026

- A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

**Requisition ID: **R398165

Associate Director, Outcomes Research

**Job Description**

The **Senior Director (Sr. Principal Scientist) ** has primary responsibility for the strategic planning and directing clinical research activities involving investigational compounds in Immunology. With a focus on late-stage development, the Senior Clinical Director will manage the entire cycle of clinical development, including determination of appropriate disease indications to pursue and subsequent study design, initiation, execution, monitoring, analysis, regulatory filing, and publication.

**Specifically, The Senior Director May Be Responsible For**

- Evaluating pre-clinical and translational work for the purpose of generating the early clinical development plan and Investigational New Drug applications.

- Providing clinical development support of business development assessments of external opportunities to grow the Immunology Pipeline

- Developing clinical development strategies for investigational drugs and planning clinical trials (design, operational plans, settings) based on these clinical development strategies.

- Monitoring and managing the conduct of ongoing or new clinical trials for investigational drugs.

- Analyzing and summarizing the clinical findings from studies to support decisions regarding safety and efficacy as well as new drug applications, clinical study reports, or publication; and

- Participation in internal and joint internal/external research project teams relevant to the development of new compounds

**The Senior Director May**

Supervise the activities of Clinical Scientists in the execution of clinical studies. Work closely with a cross-functional group of experts in commercialization, regulatory affairs, statistics, and manufacturing to manage clinical development projects; and assist the Executive Director in ensuring that appropriate Corporate personnel is informed of the progress of studies of our company and competitors' drugs and internal and external expert opinion on scientific questions relevant to his/her areas of responsibility.

The Senior Director is responsible for maintaining a strong scientific fund of knowledge by:

- Maintaining awareness of scientific developments within his/her area of expertise, in terms of new scientific findings, research methodologies

- Identification of scientifically and operationally strong investigators who can assist in the development of our company's investigational drugs in Immunology.

- Establishing collaborative relationships with external experts in Rheumatology, Gastroenterology, Dermatology, Pulmonary, or rare diseases, particularly those whose research focus and expertise can inform and assist the evaluation of the company's investigational drugs.

- Attending appropriate scientific meetings to maintain his or her competency and to maintain awareness of research activities in his/her area of responsibility.

**To Accomplish These Goals, The Senior Director May**

- Author detailed development documents, presentations, budgets, and position papers for internal and external audiences.

- Facilitate collaborations with external researchers around the world.

- Travel on company business about twenty (20) percent of the time to manage future or ongoing clinical research projects.

**Qualifications**

**Education minimum required:**

M.D., D.O., M.D./Ph.D, or D.O./PhD..

**Required Experience And Skills**

- Experience in the design and/or execution of phase 2 or 3 clinical trials specifically in Immunology

- Minimum of 3 years of clinical medicine experience

- Minimum of 5 years of industry experience in drug development

- Demonstrated record of scientific scholarship and achievement

- Strong interpersonal skills, as well as the ability to work collaboratively in a cross-functional team environment.

**Required Skills**

Clinical Development, Clinical Documentation, Clinical Immunology, Clinical Judgment, Clinical Medicine, Clinical Research Management, Clinical Sciences, Clinical Studies, Clinical Trial Development, Data Analysis, Drug Development, Hiring, Ophthalmology, Rare Diseases, Scientific Consulting, Strategic Planning

**Preferred Skills**

Current Employees apply HERE

Current Contingent Workers apply HERE

**US And Puerto Rico Residents Only**

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

**Requirements**

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

**U.S. Hybrid Work Model**

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.

The salary range for this role is

$282,200.00 - $444,200.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

**San Francisco Residents Only: ** We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

**Los Angeles Residents Only: ** We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

**Search Firm Representatives Please Read Carefully**

Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

**Employee Status**

Regular

**Relocation:**

**VISA Sponsorship**

**Travel Requirements:**

**Flexible Work Arrangements**

Hybrid

**Shift**

**Valid Driving License:**

**Hazardous Material(s)**

**Job Posting End Date:**

04/23/2026

- A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

**Requisition ID: **R389095

Senior Principal Scientist, Clinical Research, Immunology - Ophthalmology

Seit mehr als 135 Jahren erforscht, entwickelt und produziert Boehringer Ingelheim neue Medikamente mit hohem therapeutischem Nutzen für Mensch und Tier. Als Pharmaunternehmen in Familienbesitz planen wir langfristig und investieren daher besonders in die Forschung und Entwicklung. Wir sind stolz, so einige der größten Gesundheitsprobleme unserer Zeit angehen zu können. Unsere Vision „Werte schaffen durch Innovation“ hat unsere Zusammenarbeit seit jeher geprägt und ist für uns Anspruch und Antrieb zugleich. Mit Hauptsitz in Ingelheim, Deutschland, beschäftigt Boehringer Ingelheim weltweit insgesamt rund 53.000 Mitarbeiter. Weitere Informationen zu Boehringer Ingelheim finden Sie unter www.boehringer-ingelheim.de

Industry: Arzneimittelherstellung
Company Size: 10.001+ Beschäftigte

Boehringer Ingelheim

**Description**

The Department of Computational Innovation at Boehringer Ingelheim is seeking a highly motivated and accomplished Senior Principal Scientist to drive in silico evidence generation and advance novel therapeutic candidates (NTCs) through various milestones. This pivotal role will be instrumental in advancing our understanding of disease mechanisms and driving drug discovery efforts for new and underserved autoimmune disease indications. This role will leverage advanced computational approaches, particularly in bioinformatics, to elucidate NTC Mechanisms of Action (MoA) to facilitate late-stage project transitions in relevant patient segments.

The successful candidate will be a key contributor to our interdisciplinary team, collaborating closely with the Department of Immunology and Respiratory Disease Research (I&R), as well as in vitro and in vivo biologists. You will play a pivotal role in developing and applying cutting-edge omics-based approaches to accelerate drug discovery and development.

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies' success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees

**Duties & Responsibilities**

-  In Silico Evidence Generation: Drive the generation of robust in silico evidence packages to support the progression of NTCs through critical development milestones.

-  Bioinformatics Project Leadership: Lead and execute bioinformatics projects to deliver innovative NTC MoA insights, with a particular emphasis on dermatological applications.

-  Advanced Computational Approaches: Leverage single and spatial omics technologies, machine learning/AI techniques, biological knowledge, and deep disease understanding to build compelling in silico evidence packages.

-  Clinical Biomarker & Safety/Toxicity Contribution: Contribute to clinical biomarker discovery efforts and/or data-driven safety and toxicity assessments.

-  Cross-Functional Collaboration: Work closely with colleagues in I&R, as well as in vitro and in vivo biologists, to integrate computational findings with experimental data.

-  Omics-Based Approach Development: Develop and implement novel omics-based computational approaches to address key challenges in drug development.

-  Drug Development Contribution: Apply computational expertise to various stages of the drug development pipeline, from target identification to late-stage clinical development.

**Requirements**

-  Ph.D. in Bioinformatics, Computational Biology, Immunology, Molecular Biology, or a related discipline with 7 or more years of relevant post-doctoral and/or industry experience in drug discovery and development, with at least three (3) years of experience in drug discovery.

-  Demonstrated expertise in understanding complex disease mechanisms, particularly within immunology, dermatology, and/or rheumatology.

-  Expertise in bioinformatics, including the analysis of large-scale biological datasets (e.g., single-cell RNA-seq, spatial transcriptomics, genomics, proteomics).

-  Proficiency in machine learning and artificial intelligence techniques for biological data analysis.

-  Strong understanding of immunology and disease mechanisms, particularly in the context of dermatology and rheumatology.

-  Experience collaborating with experimental biologists (in vitro and in vivo) to design experiments and interpret results.

-  Demonstrated ability to translate complex computational findings into clear and actionable insights for drug development teams.

-  Excellent communication, interpersonal, and presentation skills.

-  Proven ability to work independently and as part of a highly collaborative, multidisciplinary team.

-  Provides expert-level scientific and bioinformatics expertise within the area(s) of biology and human disease addressed by the TA.

-  Knowledge of current key datasets, therapeutic landscape and demographic/epidemiological considerations within TA is required.

Preferred Qualifications:

-  Experience with clinical biomarker discovery or data-driven safety & toxicity assessment.

-  Familiarity with regulatory requirements and guidelines in drug development.

-  Prior experience in dermatology and rheumatology research.

Eligibility Requirements:

-  Must be legally authorized to work in the United States without restriction.

-  Must be willing to take a drug test and post-offer physical (if required)

-  Must be 18 years of age or older

@computationalinnovation

**Compensation Data**

This position offers a base salary typically between $170,000.00 and $269,000.00 USD. The position may be eligible for a role specific variable or performance based bonus and or other compensation elements. For an overview of our benefits please click here .

Our Company

**Why Boehringer Ingelheim?**

With us, you can develop your own path in a company with a culture that knows our differences are our strengths - and break new ground in the drive to make millions of lives better.

Here, your development is our priority. Supporting you to build a career as part of a workplace that is independent, authentic and bold, while tackling challenging work in a respectful and friendly environment where everyone is valued and welcomed.

Alongside, you have access to programs and groups that ensure your health and wellbeing are looked after - as we make major investments to drive global accessibility to healthcare. By being part of a team that is constantly innovating, you'll be helping to transform lives for generations.

Want to learn more? Visit https://www.boehringer-ingelheim.com

Senior Principal Scientist, Portfolio In silico Evidence Lead, Computational Biology

Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious and life-threatening diseases.

We discovered and developed the first medicines to treat the underlying cause of cystic fibrosis (CF), a rare, life-threatening genetic disease. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases. 

Founded in 1989 in Cambridge, Massachusetts, our corporate headquarters is now located in Boston’s Innovation District, and our international headquarters is in London, United Kingdom. We currently employ approximately 3,500 people in the United States, Europe, Canada, Australia and Latin America with nearly two-thirds of our staff dedicated to research and development.

Vertex is consistently recognized as one of the industry’s top places to work by Science Magazine, The Boston Globe, Boston Business Journal and the San Diego Business Journal. Our research and medicines have also received esteemed recognitions, including the Robert J. Beall Therapeutics Development Award, the French Prix Galien and the British Pharmacological Society awards.

Industry: Biotechnology Research
Company Size: 1,001-5,000 employees

Vertex Pharmaceuticals

**Job Description**

**General Summary:**

The Principal Scientist/Engineer, Manufacturing Science and Technology (MSAT) – Biologics & Cell Therapy is a key technical role within the **Commercial Manufacturing and Technology Operations (CMTO) ** organization. This position supports late‑stage clinical and commercial programs across the Vertex Biopharmaceutical Sciences and Manufacturing Operations (BSMO) network, with a focus on **manufacturing process support, lifecycle management, and technical execution for biologics.**

Based at the Boston Seaport site, this role partners closely with cross‑functional internal teams and external manufacturing partners to ensure robust, compliant, and scalable manufacturing processes that enable reliable clinical and commercial supply to patients.

**Key Responsibilities**

- Provide MSAT support across biologics manufacturing processes, spanning development, technology transfer, validation, and commercial lifecycle management.

- Plan, prioritize, and execute MSAT deliverables by developing and managing timelines aligned with program milestones and supply requirements.

- Contribute as a technical team member on cross‑functional project teams, ensuring manufacturing readiness and alignment across development, manufacturing, quality, regulatory, and supply chain functions.

- Apply strong process understanding and data‑driven decision‑making to support manufacturing performance, troubleshoot process issues, and assess risks to supply.

- Author and review technical reports and process data summaries to support deviations, investigations, change controls, CAPAs, and continuous improvement initiatives.

- Support technology transfer activities between development, internal manufacturing sites, and external partners, ensuring effective knowledge transfer and process understanding.

- Serve as a technical interface with contract manufacturing organizations (CMOs) and external partners, supporting execution, issue resolution, and alignment to program objectives.

- Provide manufacturing process expertise to support regulatory submissions and respond to technical questions from global health authorities.

- Contribute to process validation, continued process verification (CPV), and ongoing process monitoring activities in support of commercial operations.

- Drive a culture of continuous improvement, supporting initiatives to enhance process robustness, efficiency, and compliance.

- Work on site a minimum of 3 days per week; approximately 10% travel is expected.

**Required Experience And Qualifications**

- Minimum of 8 years of relevant experience in the biopharmaceutical industry, or an equivalent combination of education and experience.

- Bachelor’s degree in science or engineering (e.g., chemical engineering, biochemical engineering, biology, biotechnology) or equivalent; advanced degree preferred.

- Experience supporting late‑stage and/or commercial biologics products in a cGMP manufacturing environment.

- Broad understanding of manufacturing process development, scale‑up, and lifecycle support for complex biological products.

- Working knowledge of cGMP regulations and guidance across major global health authorities (e.g., FDA, EMA).

- Experience with technology transfer, process validation, and process performance monitoring.

- Direct experience working with contract manufacturing organizations (CMOs) and/or external technical service providers.

- Experience supporting manufacturing quality systems, including deviations, investigations, change controls, and CAPAs.

- Strong written and verbal communication skills, with the ability to convey complex technical concepts to cross‑functional stakeholders.

- Demonstrated ability to work independently, manage multiple priorities, and exercise sound scientific and technical judgment.

**Pay Range**

$145,500 - $218,300

**Disclosure Statement**

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

**Flex Designation**

Hybrid-Eligible Or On-Site Eligible

**Flex Eligibility Status**

In this Hybrid-Eligible role, you can choose to be designated as:

-  Hybrid: work remotely up to two days per week; or select

-  On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

**Company Information**

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

MSAT Principal Scientist, Biologics

Monte Rosa Therapeutics is a clinical-stage biotechnology company developing highly selective molecular glue degrader (MGD) medicines for patients living with serious diseases in the areas of oncology, autoimmune and inflammatory diseases, and more. Monta Rosa’s QuEEN™ (Quantitative and Engineered Elimination of Neosubstrates) discovery engine combines AI-guided chemistry, diverse chemical libraries, structural biology and proteomics to identify degradable protein targets and rationally design MGDs with unprecedented selectivity. The QuEEN™ discovery engine enables access to a wide-ranging and differentiated target space of well-validated biology across multiple therapeutic areas. Monte Rosa has developed the industry’s leading pipeline of MGDs.

Industry: Biotechnology Research
Company Size: 51-200 employees

Monte Rosa Therapeutics

Monte Rosa Therapeutics (MRT) seeks to recruit an experienced, creative and highly talented DMPK and ADME Scientist who is eager will assit in leading the discovery and development effort to grow the drug pipelines, as well as help lead external GxP compliance research efforts. The Scientist will work MRTx colleagues to participate in all stages of DMPK and ADME assessments, from initial compound screening through to IND and NDA regulatory submissions. Working with Research, Bioanalytical and Clinical Science subject matter experts, provides scientific expertise to ensure that clinical candidates with acceptable drug development characteristics are identified and appropriately characterized. Represents Preclinical Development on Research and Development teams and regularly interfaces with internal and external colleagues to ensure timely and accurate dissemination of DMPK and ADME findings

- Work closely with the medicinal chemistry team, the Scientist Position will lead the Nonclinical Development efforts in troubleshooting and guidance to the discovery project team with a particular focus on optimizing properties for oral administration

- Represent Nonclinical Development to project teams and present our work in the interpretation of ADME experimental data related to the in vitro and in vivo animal PK and biotransformation.

- Continually learn in vitro ADME and in vivo animal PK analysis (Winnolin)

- Coordinate outsourced in vitro and in vivo DMPK studies

- Explore new technologies and capabilities in discovery DMPK space

- Strong written and oral communication to support internal communication of data, study reports and regulatory documentation.

- Ability to work on multiple projects in a matrixed organizational structure

- Aide the Nonclinical Development & Clinical Pharmacology team’s activities across multiple project phases, including lead discovery, lead optimization, and regulatory filings.

- 7+ years of drug discovery industry experience in Drug Metabolism, Pharmacokinetics, Pharmaceutical Chemistry, Toxicology, or a related scientific discipline.

- Effective management of internal and external collaborations/service providers (CROs)

- Build relationships with peers and partners outside of Nonclinical Development & Clinical Pharmacology to enable high team performance.

- Demonstrates novel, innovative solutions to challenging problems using an extremely high degree of scientific discretion, intuition, and integrity.

- Strong collaboration and innovative skills across subject areas representing DMPK as a project team representative within the core team is a key requirement.

Experience in the design, conduct, and interpretation of in vitro and in vivo ADME and animal PK studies

Scientist,  ADME & BioAnalytical

**Company Description**

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onX,Facebook,Instagram,YouTube,LinkedInandTik Tok.

**Job Description**

As **Senior Engineer **, you will conceive and execute novel scientific research or development that achieves projects and area goals. Generate new scientific proposals and lead those efforts. Investigate, identify, develop, and optimize new methods and techniques. Act as a lead scientist in his/her area of expertise and critically evaluate relevant scientific and regulatory advances and integrate this knowledge into research or development programs.

**Responsibilities**

- Demonstrate the ability to resolve key project hurdles and assumptions by effectively utilizing available information and technical expertise.

- Publish research in peer-reviewed journals and present work at scientific conferences.

- Proactively seek out new information in the literature and incorporate this into individual project(s) as well as the overall program.

- Seize opportunities to pursue project relevant leads that are in line with the groups strategy.

- Maintain a high level of productivity in the lab.

- Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug and radioactive compounds, GxP compliance, and animal care where applicable.

- May mentor/supervise a team of one or more and guide and evaluate the performance of those individuals; is accountable for the effective performance of the team/individuals.

**Qualifications**

- Bachelors Degree or equivalent education and typically 12 years of experience, Masters Degree or equivalent education and typically 10 years of experience, PhD and typically 4 years of experience.

- Possess thorough theoretical and practical understanding of own scientific discipline.

- Effective writer and communicator of research or other regulatory materials.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

- The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeofthis posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location,andwemayultimatelypaymore or less than the posted range. This range may bemodifiedin thefuture.

- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.

- This job is eligible toparticipatein our short-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of anybonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company's soleandabsolutediscretion unless and until paid andmay bemodifiedat the Companys sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

Senior Systems Engineer

The mission of the University of Michigan is to serve the people of Michigan and the world through preeminence in creating, communicating, preserving, and applying knowledge, art, and academic values, and in developing leaders and citizens who will challenge the present and enrich the future.

Why Work at Michigan?

Being part of something greater, of serving a larger mission of discovery and care — that's the heart of what drives people to work at Michigan. In some way, great or small, every person here helps to advance this world-class institution. It's adding a purpose to your profession. Work at Michigan and become a victor for the greater good.

Industry: Higher Education
Company Size: 10,001+ employees

University of Michigan

Responsibilities*

The University of Michigan, School of Nursing is currently seeking a Research Assistant to support the Principal Investigator on two grant funded studies. The first is a pilot intervention study to improve physical activity behaviors of older adults with pre-frailty who reside in independent living communities. The second study assesses whether smartphone-based cognitive tests, paired with physical activity monitoring can be used to measure cognitive function and physical acitivity in real time among older adults in assisted living communities.

**The specific duties of the position include (but are not limited to):**

- Participate in the recruitment, screening, scheduling, and follow-up of research participants.

- Manage, track, and record data from physical activity monitors, physical performance tests, cognitive tests, and survey questionnaires.

- General administrative support of the project, data collection, analysis, and dissemination.

Desired Qualifications*

**Education And Experience**

- Kinesiology or physical rehabilitation experience/training preferred.

- Prior research experience preferred.

- Candidate must have excellent communication skills, with the ability to receive and convey information clearly and concisely for various mediums.

- Excellent computer skills, including knowledge of Microsoft Office products (including Word, Excel).

**Attributes**

- Candidate must have excellent attention to detail and organizational skills.

- Demonstrated time management and relationship building skills.

- Demonstrated ability to multi-task and work independently with minimal supervision with diverse teams of people in a diplomatic, collaborative and effective manner.

- Knowledge or ability to learn Qualtrics and RedCap preferred.

- Ability to serve diverse populations.

- A high degree of initiative and resourcefulness

- Ability to travel to senior living communities is Southeast Michigan. Must have a valid driver's license.

Modes of Work

Positions that are eligible for hybrid or mobile/remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about the work modes.

U-M EEO Statement

The University of Michigan is an equal employment opportunity employer.

RESEARCH ASST I (TEMP)

Flatiron Health’s mission is to improve and extend lives by learning from the experience of every person with cancer.

Industry: Biotechnology Research
Company Size: 1,001-5,000 employees

Flatiron Health

Reimagine the infrastructure of cancer care within a community that values integrity, inspires growth, and is uniquely positioned to create a more modern, connected oncology ecosystem.

We’re looking for a Senior Research Scientist to help us accomplish our mission to improve lives by learning from the experience of every cancer patient. Are you ready to be the next changemaker in cancer care?

**What You'll Do**

In this role, you will work as a member of the Research Sciences (RS) department, primarily supporting the Custom Solutions and Services (CSS) team within the Client Solutions organization. This team provides customized real-world data and real-world evidence solutions to address the most important research questions across clinical development, market access, and commercial use cases for our life sciences partners. As part of CSS, you will:

- Act as a principal investigator on client-facing RWE solutions engagements, accountable for the study design, analytics specification, conduct, and reporting of real-world oncology studies

- Design and execute studies leveraging predictive modeling and causal inference methodologies to support evidence generation and decision-making for medical affairs, clinical development, and related strategic use cases.

- Collaborate with cross-functional stakeholders to devise proposals for RWE data, analytics, and consulting solutions for customer use cases across the oncology product lifecycle

- Engage with clients to drive demand and buy-in for study concepts by demonstrating a deep understanding of the strategic scientific context behind a customer's asset, EHR-derived real-world data, and epidemiologic approaches

- Provide scientific oversight to study team co-investigators and programmers to produce high quality client-facing protocols and statistical analysis plans, ensure accurate implementation of analyses in accordance with study plans, and report valid and reliable results

- Have accountability over project scope, including identifying scope expansion and the need for amendments or additional project budget to complete additional research objectives requested by clients

- Drive repeat business with external stakeholders by fostering a collaborative, productive research environment and through successful delivery of scientifically rigorous study materials

**Who You Are**

You're a kind, passionate and collaborative problem-solver who values the opportunity to think beyond the way things are. In addition, you’re an analytical thinker and excellent communicator with experience or interest in designing studies and analyzing real-world data (e.g., healthcare claims or electronic health records). You are excited by the prospect of rolling up your sleeves to tackle meaningful problems each and every day.

- You hold a Master’s degree in Epidemiology, Biostatistics, Health Economics and Outcomes Research, Data Science (or closely related field) with 7-8 years of relevant experience or a PhD with 4-5 years of relevant experience.

- You have experience in oncology and a deep understanding of observational data and have a track record of success applying epidemiologic approaches and advanced statistical methods to problems in the public health and/or pharmaceutical industry

- You are familiar with predictive modeling or AI methods for solutions supporting oncology clinical development, RWD/RWE, or other regulated healthcare decision-making contexts

- You have experience contributing to the development of machine learning or predictive modeling solutions for clinical research or clinical care applications such as digital twins or clinical trial simulations

- You are proficient in R programming

- You have experience with EHR-derived real-world data and/or claims data

- You have consulting experience within the healthcare domain and are skilled at building and navigating client relationships

- You are an excellent communicator, with experience drafting and developing complex, technical documentation and delivering presentations to scientific audiences

- You have strong organizational, time-management, prioritization and decision-making skills necessary to evaluate, plan and implement multiple high-visibility projects in a timely fashion

- You have the ability to work effectively in a fast-moving, constantly changing, diverse, and matrix environment

- You are passionate about our mission to improve healthcare through technology

- You can deliver messages in a clear and concise way and can articulate complex information to clients in an easy-to-digest format

**Where you’ll work**

In this hybrid role, you’ll have a defined work location that includes work from home and 3 office days set by you and your team. For more information on our approach to hybrid work, please visit the how we work website.

Flatiron Health is proud to be an Equal Employment Opportunity employer.

We do not discriminate based upon race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics.

Senior Research Scientist (RWE) - Custom Solutions and Services

**The Role**

Moderna is seeking a Scientist to join the Analytical Development team in Norwood, MA. This individual will play a critical role in developing, optimizing, and implementing advanced analytical methods that support Moderna’s expanding therapeutic and vaccine portfolio. The successful candidate will generate high-quality data to drive method development, process understanding, and analytical readiness across new programs and manufacturing platforms.

The ideal candidate is hands-on, detail-oriented, and thrives in a collaborative, fast-paced environment. This role requires strong technical skills in chromatography, spectroscopy, and separation sciences, along with the ability to manage multiple projects and communicate effectively with cross-functional partners in Analytical Development, Process Development, and Quality.

**Here’s What You’ll Do**

- Develop and execute analytical methods, including mass spectrometry and HPLC with various detector configurations, to assess Moderna’s plasmid, mRNA, and LNP-based products.

- Perform intact mass analysis and primary structure characterization of proteins.

- Develop LC-MS/MS methods for qualitative and quantitative protein analysis.

- Generate feasibility data and support method development and optimization for novel platforms, including new plasmid manufacturing approaches and oncology programs.

- Collaborate cross-functionally with Research Analytics, Process Development, Quality Control, and Analytical Technical Operations to support method development, qualification, investigations, and technology transfer.

- Document experimental work in electronic lab notebooks and author technical reports, summaries, and method implementation documents.

- Maintain and troubleshoot LC-MS instrumentation, including Orbitrap, Q-TOF, and triple quadrupole systems.

- Maintain a strong focus on quality and data integrity, ensuring compliance with internal standards and regulatory expectations.

**Here’s What You’ll Need (Basic Qualifications)**

- PhD degree with 0-2 years or MS degree with 5+ years of relevant industry experience in Analytical Chemistry, Biochemistry, Chemistry, or related discipline.

- 4-5 years hands-on experience in LC-MS, HPLC, UV/Vis, spectroscopy, MAM workflows.

- Proficiency in software tools for MS data analysis (Xcalibur, MassHunter, Skyline, Biopharma Finder, Protein Metrics)

- Proven ability to perform method development, troubleshooting, and data analysis in support of biologics, RNA, or complex formulations.

- Familiarity with regulatory guidance, method transfer, and collaboration with Quality in a regulated environment is required.

- Familiarity with LNP characterization or nucleic acid-based analytical methods is a plus.

- Strong technical writing and documentation skills.

- Excellent organizational and multitasking ability in a fast-paced environment.

- Demonstrated collaboration and communication skills to work effectively with cross-functional teams.

- Highly motivated, scientifically curious, and capable of working independently with minimal supervision.

- This position is site-based, requiring you to be at Moderna’s site full-time. This position is not eligible for remote work.

**Pay & Benefits**

**At Moderna, we believe that when you feel your best, you can do your best work. That’s why our US benefits and global well-being resources are designed to support you—at work, at home, and everywhere in between.**

- Best-in-class healthcare coverage, plus voluntary benefit programs to support your unique needs

- A holistic approach to well-being, with access to fitness, mindfulness, and mental health support

- Family planning benefits, including fertility, adoption, and surrogacy support

- Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown

- Savings and investment opportunities to help you plan for the future

- Location-specific perks and extras

The salary range for this role is $109,200.00 - $174,600.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual’s position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs. The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance.

**About Moderna**

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.

**Our Working Model**

As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact.

Moderna is a smoke-free, alcohol-free, and drug-free work environment.

**Equal Opportunities**

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law.Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.

**Accommodations**

We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at leavesandaccommodations@modernatx.com.

Export Control Notice This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant’s ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role Moderna is unable to sponsor non-U.S. persons to apply for an export control license.

Scientist, Analytical Development

Wiley’s leading media brand providing first-hand information on the global chemical, life science and process industries

Industry: Zeitungsverlage
Company Size: 201–500 Beschäftigte

CHEManager International

Umoja Biopharma is an industry-leading biotech with locations in Seattle, WA and Louisville, CO, focused on transforming the treatment of cancer with a novel integrated immunotherapy platform. Our vision is to develop off-the-shelf therapies capable of treating any tumor, any time. We are a diverse and growing team working in brand-new facilities in downtown Seattle, Washington and Louisville, Colorado, and we are looking for innovative thinkers who are excited by groundbreaking science and technology, and passionate about squaring up to the challenges inherent to cutting-edge drug development. We are committed to our core values and principles that support our overall mission and strongly invite applications from enthusiastic individuals who share our commitment and help position Umoja to deliver on our goals. We at Umoja believe in the importance of stories; we are looking for great people to join our team to help us create more stories for ourselves, for you, and most importantly for patients and their families.

Umoja Biopharma - Your Body. Your Hope. Your Cure.

**Position Summary**

Umoja Biopharma is seeking a driven Scientist to understand and assess the potency of lentiviral drug products. This role will develop early- and late-stage potency methods for release of drug substance/product and generate data packages to support regulatory submissions. The position will work closely with other functions to deliver qualified/validated QC release and characterization assays, generate associated documentation, and oversee transfer of methods internally or externally to a CMO/CRO.

As a laboratory-based position within the technical operations organization, this position will play a critical role in advancing Umoja's pipeline and analytical development capabilities.

This role will be onsite 5 days/week based out of our Seattle, WA location.

**Core Accountabilities**

**Specific responsibilities include:**

- Successful design, execution, analysis, and documentation of experiments to develop analytical methods and key data packages for lentiviral gene therapies.

- Perform experiments to support analytical development and product characterization using advanced techniques including multicolor flow cytometry, ELISAs, Western blots, qPCR/dPCR, signal transduction and cytokine assays.

- Oversee the qualification of analytical methods.

- Author, review and approve technical documents including electronic notebook entries, standard operating procedures, test methods, technical reports, etc.

- Present findings on method development and communicate interpretation and strategic plans related to the potency of our drug product to cross-functional teams.

- Foster good teamwork and communication. Build a reputation of excellence as an individual and as a team.

- Collaborate with stakeholders within Analytical Development (Product Sciences and Process Analytics teams) and cross-functionally with Quality Control, CMC, Translational Medicine, Process Sciences, Discovery, and Vector Biology

- All other duties as assigned

**The Successful Candidate Will Have**

- PhD/MS/BS in Immunology, Cellular Biology, Molecular Biology or related discipline with at least 0+/8+/10+ years of experience, respectively; equivalent combination of education and experience will be considered

- Proven track record in cell-based method development, including troubleshooting assays, experimental design, execution, and evaluation of data

- Ability to work in a fast-paced environment with broad responsibilities, meet deadlines, and prioritize work on multiple projects

- Strong communication skills in technical writing and oral presentation. Respectful of others and open to new ideas.

**Preferred Qualifications**

- Hands-on experience with multicolor flow cytometry, cell-based assays, ELISAs, viral transduction, and qPCR/dPCR

- Experience qualifying and transferring analytical methods to a QC lab or CMO/CRO

- Experience developing and qualifying potency methods according to ICH/USP guidelines and authoring method documentation

**Physical Requirements**

- Ability to perform standard laboratory tasks with appropriate PPE

- Perform physical tasks required to support laboratory work, including standing, walking, bending, kneeling, sitting, working with your hands in a biosafety cabinet, and occasionally moving materials up to 50 pounds

- Ability to spend prolonged periods of time working on a computer

- Ability to work onsite 5 days/week

**Salary Range: $122,000 - $150,800**

**Benefits Offerings**

Umoja Biopharma offers its employees competitive Medical, Dental, and Vision plans. Additionally, we offer Umojians access to a 401k plan through Fidelity, with a 100% match up to their first 4% deferral. Umoja also provides a generous Paid Time Off policy, employee commuter benefits, and cell phone stipend. For a full breakdown of our benefits offerings, please see the **Benefits ** section of our website.

We are America’s first research university, founded in 1876 on the principle that by pursuing big ideas and sharing what we learn, we can make the world a better place. For more than 140 years, our faculty and students have worked side by side in pursuit of discoveries that improve lives.

Johns Hopkins enrolls more than 24,000 full- and part-time students throughout nine academic divisions. Our faculty and students study, teach, and learn across more than 260 programs in the arts and music, the humanities, the social and natural sciences, engineering, international studies, education, business, and the health professions.The university has four campuses in Baltimore; one in Washington, D.C.; one in Montgomery County, Maryland; and facilities throughout the Baltimore-Washington region as well as in China and Italy.

The university takes its name from 19th-century Maryland philanthropist Johns Hopkins, an entrepreneur who believed in improving public health and education in Baltimore and beyond.

Industry: Higher Education
Company Size: 10,001+ employees

The Johns Hopkins University

Johns Hopkins University (JHU) is seeking an experienced, results-driven **Legal Operations Advisor ** to lead the design, buildout, and continuous improvement of the operational infrastructure supporting the Sr. Vice President and Office of the General Counsel (OGC). This newly created role will work in direct partnership with OGC leadership, including the General Counsel, Deputy General Counsel, Practice Group Leaders, and Chief of Staff, to ensure the operational efficiency and effectiveness of the office.

This position will oversee a range of legal operations functions, including maintaining and developing workflows, budget management frameworks, technology strategies, performance metrics, and change management. The role also collaborates regularly with Practice Group Leaders, and university administrative leaders to ensure alignment with the General Counsel's vision and institutional priorities.

**Specific Duties & Responsibilities**

~~Operational Leadership, Process/System Improvement and Project Management~~

- Anticipate, identify and troubleshoot issues of operational concern or significance within the Office of General Counsel.

- Manage complex, cross-functional projects from inception to completion across OGC practice groups, applying rigorous project management methodologies to deliver initiatives on time and within budget.

- Partner with the Chief of Staff to create, implement and maintain a standardized legal intake system.

- Manage the continuous improvement and maturation of operational processes and workflows to enhance efficiency, consistency, and effectiveness across the department, including standardizing tools, templates, and playbooks to promote best practices across practice groups.

- Assess and refine current practices and systems—such as legal holds, intake, and matter management and triage—to improve usability, scalability, and alignment with institutional needs.

~~Legal Technology Strategy~~

- Work in partnership with the Chief of Staff and Practice Group leaders to develop and execute OGC's legal technology roadmap. This includes evaluating and implementing matter management systems, e-billing platforms, contract lifecycle management solutions, e-discovery tools, and document automation platforms. Serve as primary liaison with university IT, procurement, and external vendors to ensure effective deployment, integration, and adoption.

~~Budget, Financial Management, and Outside Counsel~~

- Assist with OGC's annual budget planning process in coordination with university finance, analyzing legal spending patterns and identifying cost savings.

- Develop and enforce guidelines governing outside counsel retention, billing compliance, and spend management, leveraging data and analytics to evaluate firm performance and inform retention decisions.

~~Data Analytics and Performance Metrics~~

- Partner with internal subject matter experts to develop dashboards and reports on matters, workload, outside counsel spend, cycle times, and other indicators of departmental performance to support data-driven decision-making and strategic planning.

~~Change Management and Communication~~

- Work in alignment with the Chief of Staff to function as a change agent within OGC and drive the adoption of new processes and technologies across attorneys, paralegals, and staff. Manage design, rollout, and training for all new systems and processes.

~~Team Leadership and Cross-Functional Collaboration~~

- Collaborate with cross-functional partners — including the offices of the President and Provost, Finance, HR, IT, Compliance, and Risk Management — to align OGC operations with broader institutional goals.

- Build and maintain successful working relationships that support university-wide collaboration, and a strong focus on customer service and positive stakeholder engagement.

- Other duties as assigned.

**Minimum Qualifications**

- Bachelor’s degree from an accredited university.

- Minimum five (5) years of increasing responsible experience in strategic management, legal operations, legal administration, senior paralegal experience, or law practice management, gained in-house, in the government, or at a law firm.

- Additional education may substitute for required experience, to the extent permitted by the JHU equivalency formula.

- Strong communication, organizational, and interpersonal skills.

- Proven capacity for tactful collaboration and always ensuring confidentiality.

**Preferred Qualifications**

- Demonstrated ability to manage complex, cross-functional projects using formal project management methodologies.

- Proven experience modernizing or building new legal operations functions, workflows, or systems.

- Exceptional written and oral communication skills, including the ability to share presentations and influence senior leadership and diverse stakeholder groups.

- Proficiency with legal operations technologies, including matter management systems, e-billing software, and document management tools.

- Experience working with analysis software such as Power BI, Onit, Tableau, and Excel

- Demonstrated ability to drive organizational change and technology adoption across diverse teams.

- Project management-related certifications and training (e.g., PMP, CAPM, Lean Six Sigma).

**Technical Skills & Expected Level Of Proficiency**

- Budgeting - Intermediate

- Project Planning - Intermediate

- Critical Thinking - Intermediate

- Operational Oversight - Intermediate

- Process Improvement - Intermediate

- Project Management - Intermediate

- Project Documentation - Intermediate

- Resource Management - Intermediate

- Strategic Thinking - Intermediate

- Workflow Management - Intermediate

~~The core technical skills listed are most essential; additional technical skills may be required based on specific division or department needs.~~

Classified Title: Legal Operations Advisor

Role/Level/Range: ATP/04/PF

Starting Salary Range: $85,500 - $149,800 Annually (Commensurate w/exp.)

Employee group: Full Time

Schedule: Monday - Friday 8:30am - 5:00pm

FLSA Status: Exempt

Location: Hybrid/Homewood Campus

Department name: VP and General Counsel Administration

Personnel area: University Administration

Legal Operations Advisor (VP and General Counsel Office)

Sundt Construction, Inc. is one of the country’s most respected general contractors, currently ranked in the top 100 largest construction companies in the United States by ENR, the industry’s principal trade magazine. We're consistently ranked a Best Place to Work by our own employees and known nationally for our innovative approach to construction services. We've also won more Build America awards from the Associated General Contractors of America than any other general contractor.   

Sundt is a full-service building contractor with expertise that spans the entire lifecycle of construction. We offer Construction Management at Risk, Design-Build and Build to Suit Contracting, and can work within your preferred delivery system, including the traditional Design-Bid-Build approach. We also provide a host of services as Construction Managers and Program Managers, serving as your agent for managing the entire project development process for you, whether you have a single- or multiple-project program.

Please check out our website (www.sundt.com) to browse our capabilities and review our career opportunities. We're an industry leader looking for the industry's best talent. Come find your next career opportunity with us!

Industry: Construction
Company Size: 1,001-5,000 employees

Sundt Construction

**Job Description**

As a 100% employee-owned contractor, when you work at Sundt, you’re not just hiring on at a company, you’re joining a culture. Because everyone at Sundt is part owner, you’ll join a team of people who are deeply invested in their work. From apprentices to managers, we’re passionate about the details and deliberate in everything we do.

**Job Summary**

The Director, Operations Finance, [Business Group] provides executive support to the [Business Group] President in leading a growing $1 billion revenue division of the Company. Supported with staff from Sundt Corporate Finance & Accounting team, the Director, Operations Finance is responsible for all financial, accounting and strategic planning activities for the Group, assisting Group leadership in analysis and forecasting of financial results and the achievement of annual performance goals.

**Key Responsibilities**

-  Assist Group President and leadership with ad hoc financial-related matters.

-  Collaborating with Sundt data analytics team, maintain and augment Group reporting to suit leadership evolving needs.

-  In consultation with Group leadership, lead update of fiscal year forecast on monthly basis, reflecting current period project progress reports.

-  Serve as primary financial advisor to the Group President and their leadership team.

-  Support Group leadership oversight of project performance, participating in monthly project progress reviews and helping leadership deliver optimal margin and cash flow.

-  Support periodic requests from Corporate Finance & Accounting relating to the annual audit or production of financial reporting.

-  Support the strategic planning effort, coordinating development of delivery and implementation of annual budget and capital needs.

-  Working with Sundt Corporate Finance & Accounting team, analyze monthly Group financial results, providing variance analyses to budget and prior year periods and identifying areas of financial risk (aged AR, under billings, etc.)

**Minimum Job Requirements**

-  Bachelors Degree in Accounting, Finance, or related field required. Exceptional candidates with a degree in Construction Management also will be considered.

-  Collaborative with demonstrated success working in virtual teams.

-  Enthusiastic learner with leadership ambitions.

-  Excellent written and verbal communication skills.

-  Familiarity with JD Edwards Enterprise One a plus.

-  High integrity and results-oriented mindset.

-  Minimum 7 years of progressive finance and accounting experience.

-  Project accounting experience in Construction industry required.

-  Strong financial modeling skills, with demonstrated ability to develop bespoke analysis.

Note: Job Description is subject to change at any time and may include other duties as assigned.

**Physical Requirements**

-  May stoop, kneel, or bend, on an occasional basis

-  Must be able to comply with all safety standards and procedures

-  Required to use hands to grasp, lift, handle, carry or feel objects on a frequent basis

-  Will interact with people and technology frequently during a shift/work day

-  Will lift, push or pull objects up to 50Ibs on an occasional basis.

-  Will sit, stand or walk short distances for up to the entire duration of a shift/work day.

-  Will use telephone, computer system, email, and other electronic devices on a frequent basis to communicate with internal and external customers or vendors

**Equal Opportunity Employer Statement: ** Sundt is committed to the equal treatment of all employees, and/or applicants for employment, and prohibits discrimination based on race, religion, sex (including pregnancy), sexual orientation, gender identity, color, age, disability, national origin, covered veteran status, genetic information; or any other classification protected by applicable Federal, state, or local laws.

**Benefit list:**

Market Competitive Salary (paid weekly)

Bonus Eligibility based on company, group, and individual performance

Employee Stock Ownership Plan & 401K

Industry Leading Health Coverage Starting Your First Day

Flexible Time Off (FTO)

Medical, Health Savings, and Wellness credits

Flexible Spending Accounts

Employee Assistance Program

Workplace Wellness Programs

Mental Health Program

Life and Disability Insurance

Employee-Owner Perks

Educational Assistance

Sundt Foundation - Charitable Employee-Owner's program

**About Us**

As a 100% employee-owned contractor, when you work at Sundt, you’re not just hiring on at a company, you’re joining a culture. Because everyone at Sundt is part owner, you’ll join a team of people who are deeply invested in their work. From apprentices to managers, we’re passionate about the details and deliberate in everything we do.

At Sundt we focus on building long-term prosperity for our clients, communities and employee-owners. We offer competitive pay, industry-leading benefits including a 401k and employee stock ownership plan, incentive programs for craft and administrative employees as well as training that focuses on your personal and professional growth. We’re driven by skill, grit and purpose. Join us as we strive to be the most skilled builder in America.

**Equal Opportunity Employer Statement: **Sundt is committed to the equal treatment of all employees, and/or applicants for employment, and prohibits discrimination based on race, religion, sex (including pregnancy), sexual orientation, gender identity, color, age, disability, national origin, covered veteran status, genetic information; or any other classification protected by applicable Federal, state, or local laws.

**Benefit list:**

- Market Competitive Salary (paid weekly)

- Bonus Eligibility based on company, group, and individual performance

- Employee Stock Ownership Plan & 401K

- Industry Leading Health Coverage Starting Your First Day

- Flexible Time Off (FTO)

- Medical, Health Savings, and Wellness credits

- Flexible Spending Accounts

- Employee Assistance Program

- Workplace Wellness Programs

- Mental Health Program

- Life and Disability Insurance

- Employee-Owner Perks

- Educational Assistance

- Sundt Foundation - Charitable Employee-Owner's program

Director of Operations - Finance

Industry: Medical Practices
Company Size: 2-10 employees

BAYFRONT HEALTH

Prepares all hot food items for both patient and non-patient food services, following all production plans and recipes as assigned by the

Executive Chef, Food & Nutrition Supervisor or Production Leader.

 Assists as needed in tray assembly, preparing of special diet needs (puree meals, supplements or non-patient services.

 Knows basic food preparation techniques including receiving, storing, preparation and holding of food items.

 Demonstrates a working knowledge of food service sanitation and practices infection control procedures. Is familiar with all practices

and procedures of the HAACP guidelines and adheres to them.

 Communicates proper information regarding patient, non-patient or department needs to the Executive Chef, Food and Nutrition

Supervisor, Group Leaders and peers of the food service team.

 Demonstrates a willingness to help on work that needs to be done, will help in other areas of the kitchen when necessary (i.e.,

cold prep, bakery, store room, café serving line, dish room or tray line.)

 Maintains reasonably regular, punctual attendance consistent with Orlando Health policies, the ADA, FMLA and other federal, state

and local standards.

 Maintains compliance with all Orlando Health policies and procedures.

Education/Training

 Ability to read and recognize similarities and differences between words and between series of numbers.

 Ability to write simple correspondence.

 Ability to respond to common inquiries or complaints from customers.

**Experience**

Six(6) months of fast food production or kitchen food production.

Hot Prep Cook - Food and Nutrition - Bayfront Hospital

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