BioSpace is the digital hub for life science news and jobs. We provide essential insights, opportunities and tools to connect innovative organizations and talented professionals who advance health and quality of life across the globe.

Industry: Internet News
Company Size: 11-50 employees

BioSpace

Savvy Admin PROD

**The Role**

Moderna is seeking a Scientist to join the Analytical Development team in Norwood, MA. This individual will play a critical role in developing, optimizing, and implementing advanced analytical methods that support Moderna’s expanding therapeutic and vaccine portfolio. The successful candidate will generate high-quality data to drive method development, process understanding, and analytical readiness across new programs and manufacturing platforms.

The ideal candidate is hands-on, detail-oriented, and thrives in a collaborative, fast-paced environment. This role requires strong technical skills in chromatography, spectroscopy, and separation sciences, along with the ability to manage multiple projects and communicate effectively with cross-functional partners in Analytical Development, Process Development, and Quality.

**Here’s What You’ll Do**

- Develop and execute analytical methods, including mass spectrometry and HPLC with various detector configurations, to assess Moderna’s plasmid, mRNA, and LNP-based products.

- Perform intact mass analysis and primary structure characterization of proteins.

- Develop LC-MS/MS methods for qualitative and quantitative protein analysis.

- Generate feasibility data and support method development and optimization for novel platforms, including new plasmid manufacturing approaches and oncology programs.

- Collaborate cross-functionally with Research Analytics, Process Development, Quality Control, and Analytical Technical Operations to support method development, qualification, investigations, and technology transfer.

- Document experimental work in electronic lab notebooks and author technical reports, summaries, and method implementation documents.

- Maintain and troubleshoot LC-MS instrumentation, including Orbitrap, Q-TOF, and triple quadrupole systems.

- Maintain a strong focus on quality and data integrity, ensuring compliance with internal standards and regulatory expectations.

**Here’s What You’ll Need (Basic Qualifications)**

- PhD degree with 0-2 years or MS degree with 5+ years of relevant industry experience in Analytical Chemistry, Biochemistry, Chemistry, or related discipline.

- 4-5 years hands-on experience in LC-MS, HPLC, UV/Vis, spectroscopy, MAM workflows.

- Proficiency in software tools for MS data analysis (Xcalibur, MassHunter, Skyline, Biopharma Finder, Protein Metrics)

- Proven ability to perform method development, troubleshooting, and data analysis in support of biologics, RNA, or complex formulations.

- Familiarity with regulatory guidance, method transfer, and collaboration with Quality in a regulated environment is required.

- Familiarity with LNP characterization or nucleic acid-based analytical methods is a plus.

- Strong technical writing and documentation skills.

- Excellent organizational and multitasking ability in a fast-paced environment.

- Demonstrated collaboration and communication skills to work effectively with cross-functional teams.

- Highly motivated, scientifically curious, and capable of working independently with minimal supervision.

- This position is site-based, requiring you to be at Moderna’s site full-time. This position is not eligible for remote work.

**Pay & Benefits**

**At Moderna, we believe that when you feel your best, you can do your best work. That’s why our US benefits and global well-being resources are designed to support you—at work, at home, and everywhere in between.**

- Best-in-class healthcare coverage, plus voluntary benefit programs to support your unique needs

- A holistic approach to well-being, with access to fitness, mindfulness, and mental health support

- Family planning benefits, including fertility, adoption, and surrogacy support

- Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown

- Savings and investment opportunities to help you plan for the future

- Location-specific perks and extras

The salary range for this role is $109,200.00 - $174,600.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual’s position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs. The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance.

**About Moderna**

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.

**Our Working Model**

As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact.

Moderna is a smoke-free, alcohol-free, and drug-free work environment.

**Equal Opportunities**

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law.Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.

**Accommodations**

We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at leavesandaccommodations@modernatx.com.

Export Control Notice This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant’s ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role Moderna is unable to sponsor non-U.S. persons to apply for an export control license.

Scientist, Analytical Development

Wiley’s leading media brand providing first-hand information on the global chemical, life science and process industries

Industry: Zeitungsverlage
Company Size: 201–500 Beschäftigte

CHEManager International

Umoja Biopharma is an industry-leading biotech with locations in Seattle, WA and Louisville, CO, focused on transforming the treatment of cancer with a novel integrated immunotherapy platform. Our vision is to develop off-the-shelf therapies capable of treating any tumor, any time. We are a diverse and growing team working in brand-new facilities in downtown Seattle, Washington and Louisville, Colorado, and we are looking for innovative thinkers who are excited by groundbreaking science and technology, and passionate about squaring up to the challenges inherent to cutting-edge drug development. We are committed to our core values and principles that support our overall mission and strongly invite applications from enthusiastic individuals who share our commitment and help position Umoja to deliver on our goals. We at Umoja believe in the importance of stories; we are looking for great people to join our team to help us create more stories for ourselves, for you, and most importantly for patients and their families.

Umoja Biopharma - Your Body. Your Hope. Your Cure.

**Position Summary**

Umoja Biopharma is seeking a driven Scientist to understand and assess the potency of lentiviral drug products. This role will develop early- and late-stage potency methods for release of drug substance/product and generate data packages to support regulatory submissions. The position will work closely with other functions to deliver qualified/validated QC release and characterization assays, generate associated documentation, and oversee transfer of methods internally or externally to a CMO/CRO.

As a laboratory-based position within the technical operations organization, this position will play a critical role in advancing Umoja's pipeline and analytical development capabilities.

This role will be onsite 5 days/week based out of our Seattle, WA location.

**Core Accountabilities**

**Specific responsibilities include:**

- Successful design, execution, analysis, and documentation of experiments to develop analytical methods and key data packages for lentiviral gene therapies.

- Perform experiments to support analytical development and product characterization using advanced techniques including multicolor flow cytometry, ELISAs, Western blots, qPCR/dPCR, signal transduction and cytokine assays.

- Oversee the qualification of analytical methods.

- Author, review and approve technical documents including electronic notebook entries, standard operating procedures, test methods, technical reports, etc.

- Present findings on method development and communicate interpretation and strategic plans related to the potency of our drug product to cross-functional teams.

- Foster good teamwork and communication. Build a reputation of excellence as an individual and as a team.

- Collaborate with stakeholders within Analytical Development (Product Sciences and Process Analytics teams) and cross-functionally with Quality Control, CMC, Translational Medicine, Process Sciences, Discovery, and Vector Biology

- All other duties as assigned

**The Successful Candidate Will Have**

- PhD/MS/BS in Immunology, Cellular Biology, Molecular Biology or related discipline with at least 0+/8+/10+ years of experience, respectively; equivalent combination of education and experience will be considered

- Proven track record in cell-based method development, including troubleshooting assays, experimental design, execution, and evaluation of data

- Ability to work in a fast-paced environment with broad responsibilities, meet deadlines, and prioritize work on multiple projects

- Strong communication skills in technical writing and oral presentation. Respectful of others and open to new ideas.

**Preferred Qualifications**

- Hands-on experience with multicolor flow cytometry, cell-based assays, ELISAs, viral transduction, and qPCR/dPCR

- Experience qualifying and transferring analytical methods to a QC lab or CMO/CRO

- Experience developing and qualifying potency methods according to ICH/USP guidelines and authoring method documentation

**Physical Requirements**

- Ability to perform standard laboratory tasks with appropriate PPE

- Perform physical tasks required to support laboratory work, including standing, walking, bending, kneeling, sitting, working with your hands in a biosafety cabinet, and occasionally moving materials up to 50 pounds

- Ability to spend prolonged periods of time working on a computer

- Ability to work onsite 5 days/week

**Salary Range: $122,000 - $150,800**

**Benefits Offerings**

Umoja Biopharma offers its employees competitive Medical, Dental, and Vision plans. Additionally, we offer Umojians access to a 401k plan through Fidelity, with a 100% match up to their first 4% deferral. Umoja also provides a generous Paid Time Off policy, employee commuter benefits, and cell phone stipend. For a full breakdown of our benefits offerings, please see the **Benefits ** section of our website.

Eurofins DiscoverX, the products company of Eurofins Discovery, is committed to enabling and accelerating multi-modality drug discovery and development from discovery to QC lot release. 

For drug discovery and development scientists, Eurofins DiscoverX is the trusted product solutions provider that accelerates research and drug discovery programs with confidence for cytokine receptors, checkpoint receptors, GPCRs, kinases, ion channels, epigenetics, nuclear receptors, and other target families. Eurofins DiscoverX develops and manufactures cutting edge assays, stable cell lines, ready-to-use kits (including bioassays), membrane preps, enzymes, and reagents for small molecule and biologic immuno-oncology, cytotoxicity, compound-target engagement, potency and QC lot release, pharmacotrafficking, and many other applications. These products are developed from 3 R&D and manufacturing centers of excellence – San Francisco Bay Area California (Fremont); St. Louis area, Missouri (St. Charles); and Poitiers, France.

Industry: Biotechnology Research
Company Size: 51-200 employees

Eurofins DiscoverX

**Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate. **** ****Eurofins believes it is a global leader in food, environmental, pharmaceutical and cosmetics products testing and in agroscience CRO services. It is also one of the global independent market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, CDMO, advanced material sciences and in the support of clinical studies.**

**In over just 30 years, Eurofins has grown from one laboratory in Nantes, France to over 50,000 staff across a network of more than 900 independent companies in over 50 countries and operating more than 800 laboratories. Eurofins offers a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products, as well as providing innovative clinical diagnostic testing services, as one of the leading global emerging players in specialized clinical diagnostics testing.**

**In 2021, Eurofins generated total revenues of EUR € 6.7 billion, and has been among the best performing stocks in Europe over the past 20 years.**

**Job Description**

**Come join our growing team! Eurofins DiscoverX Products, LLC is a leader in providing innovative solutions and support to the pharmaceutical industry by developing, manufacturing, and commercializing reagents, cell-based assay kits, and profiling and screening services. The holder of this position will be responsible for the development of new cell lines to support product development and client-driven custom projects.**

**Here's what you'll do:**

- Perform cloning and characterization of engineered cell lines using appropriate molecular and cell biology techniques, which may include flow cytometry, qPCR, Western blotting, immunofluorescence, EFC or other functional readouts.

- Design and perform required experiments to optimize and validate diverse cell-based assays intended for sale in our product portfolio or as custom projects for clients with minimal guidance from supervisor to move projects forward.

- Compile data, analyze and write first draft of client reports and prepare client-facing presentations.

- Perform proof-of-concept experiments to validate application of new molecular technologies to the Eurofins DiscoverX platform.

- Perform testing of cell-based assays using Eurofins DiscoverX technology platforms with client molecules and record results in company database.

- Prepare and present experimental data at group laboratory meetings.

- Work diligently to meet product development goals set by management team.

- Provide support functions to the R&D team such as ordering and maintaining reagents/supplies/equipment, maintaining accurate notes and records, and effective communication with other DiscoverX departments.

- Demonstrates and promotes the company vision

- Regular attendance and punctuality

- Applies ISO quality standards in all areas of responsibility, as appropriate

- Conducts all activities in a safe and efficient manner

- Performs other duties as assigned

- Owns the accountability and responsibility of delivering to client needs and timeliness

- Provides cross-functional support to other departments as required

- Adheres to site environmental health and safety (EHS) requirements

**Qualifications**

**The ideal candidate:**

- B.S., M.S. or Ph.D. in cell biology, biochemistry, immunology or related discipline, with a minimum of 3 years of industrial experience.

- Supervisory experience desirable, but not required

- Extensive mammalian cell culture experience with both adherent and suspension cells and demonstrated expertise in developing or running cell-based assays required.

- Experience performing flow cytometry, TR-FRET, transcriptional reporter assays, ELISA, or similar assays, preferably in 96-well and 384-well plate formats strongly preferred

- Knowledgeable in GPCR pharmacology and relevant assay readouts, and experience studying diverse cell signaling pathways desirable

- Familiar with assembling and plotting data in GraphPad Prism, SoftMax Pro, MicroSoft Excel or Powerpoint and presenting data to supervisor and peers

- Demonstrated success in independently performing advanced troubleshooting and contributes additional tactical skills

- Demonstrated ability to work efficiently and productively in a fast-paced highly collaborative team environment

- Highly motivated, detail-oriented individual with excellent problem-solving, organizational and multi-tasking skills

**Additional Information**

**Salary Range: $120,000 - $145,000/yr.**

The position is full-time, Monday-Friday, 8 a.m.- 5 p.m., with overtime as needed.

- Excellent full time benefits including comprehensive medical coverage, dental, and vision options

- Life and disability insurance

- 401(k) with company match

- Paid vacation and holidays

**Eurofins USA Discovery Services is a Disabled and Veteran Equal Employment Opportunity employer.**

Senior Scientist

We are Sanofi, an innovative global healthcare company. We chase the miracles of science to improve people’s lives. 

Our team, across some 100 countries, is dedicated to transforming the practice of medicine by working to turn the impossible into the possible. We provide potentially life-changing treatment options and life-saving vaccine protection to millions of people globally, while putting sustainability and social responsibility at the center of our ambitions.

Interactions with this account must comply with the Terms: https://bit.ly/sanofi-terms

Industry: Fabrication de produits pharmaceutiques
Company Size: + de 10 000 employés

Sanofi

**Job title **:~~Senior Scientist Automation and Advanced Modeling~~

- Location: Cambridge, MA

**About The Job**

We are seeking highly motivated individual to join our drug substance process engineering and modeling team. As a technical expert in process engineering and modeling, you will play a key role in advancing our global engineering department within Sanofi’s R&D CMC Synthetic organization. This position is located in Cambridge MA and will collaborate closely with colleagues in France to support digital development and implement new ways of working.

Your expertise in chemical engineering, process system modeling, and lab automation will be crucial in creating a self-driving lab for small molecule drug substance process development and optimization. You will help developing automated experimental workflows to generate data for model building, advancing the creation of digital twins and driving innovation in pharmaceutical process development.

We believe that lab automation and digital development are crucial for the future of process development in Pharma. By joining our team, you will be at the forefront of this transformation, using your expertise to push the boundaries of process engineering.

This is an exciting opportunity to demonstrate the benefits of process modelling and data science in a cutting-edge scientific department developing the next generation of Sanofi medicines that will improve the quality of life for patients across the world.

Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions.

**About Sanofi**

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

**Main Responsibilities**

Lab automation & data generation:

-  You will work closely with laboratory teams (process chemists, engineers, and the high-throughput experimentation team), fostering strong partnerships with scientists to deeply understand their research processes. Your goal will be to design, develop, and deploy cutting-edge automated systems, robotics, instrumentation, and digital workflows that significantly enhance the productivity and efficiency of our labs.

- You will be responsible for programming and developing automated laboratory systems. This includes supporting software development and deployment to automate workflows, integrating analytical instruments with laboratory software, and ensuring seamless communication between instruments and Sanofi's internal data management services.

- Mechanistic & data-driven model building - As part of matrix project teams, build mechanistic, hybrid, and data-driven modeling solutions to support small molecule process development. Collaborate with process development teams to integrate crystallization modeling into the overall process design and optimization workflow.

- Model deployment at scale – Assist in the development and deployment of digital twins for both batch and continuous processes, ensuring alignment with Quality by Design (QbD) principles. You will play a key role in implementing and scaling Model Predictive Control (MPC) systems, leveraging advanced process models to optimize performance in real-time, maintain product quality, and enhance operational efficiency across large-scale manufacturing environments.

- Provide concise technical presentations to communicate work to project teams, cross functional teams and management.  Document all work on projects and continuous improvements in eLNB experiments and summarize in Technical Reports.

- Establish/extend external network by providing leadership on academic, industrial, or government sponsored collaborations.  Steer collaboration projects to address gaps in scientific knowledge.

**About You**

- PhD or PhD candidate in chemical engineering, mathematics, physics or related with expected graduation date by first semester of 2027 with 0+ years of experience academic experience will be considered) OR a master's degree in chemical engineering, mathematics, or physics or related with a minimum of 4 years of experience (academic experience will be considered) OR a bachelor's degree in chemical engineering, mathematics, or physics with a minimum of 8 years of experience.

- Strong skills in writing and optimizing scripts in programming languages such as Python/Matlab/C#/Visual Basic.

- Experience with crystallization modeling and/or simulation tools (e.g., gPROMS).

- Experience in designing and implementing automated laboratory processes from the initial concept through to full deployment.

- Demonstrated ability to translate mathematical models into computer programs.

- An ability to work as part of a team, engaging other scientists with complementary skill sets in the field of pharmaceutical development.

- A change agent mentality, proposing novel approach to challenging scientific questions and exploring new modeling approaches.

**Preferred Qualifications**

- Familiarity with laboratory analytical measurement instruments or relevant work experience in a pharmaceutical sciences laboratory setting.

- Domain knowledge in small molecule process development with demonstrated industrial applications or academic publications in this field.

- Some knowledge in Multivariate Analysis, chemometrics and statistics.

- Experience in the development and scale-up of continuous processes.

**Why Choose Us**

- Bring the miracles of science to life alongside a supportive, future-focused team.

- Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

- Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

- Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

- Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.

- Help improve the lives of millions of people globally by making drug development quicker and more effective.

- Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

#GD-SA

#vhd

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

Senior Scientist Automation and Advanced Modeling

At Merck, known as MSD outside of the United States and Canada, we are unified around our purpose: We use the power of leading-edge science to save and improve lives around the world. For more than 130 years, we have brought hope to humanity through the development of important medicines and vaccines. We aspire to be the premier research-intensive biopharmaceutical company in the world – and today, we are at the forefront of research to deliver innovative health solutions that advance the prevention and treatment of diseases in people and animals. We foster a diverse and inclusive global workforce and operate responsibly every day to enable a safe, sustainable and healthy future for all people and communities. For more information, visit www.merck.com. 

This site is intended for residents of the United States and Canada and their territories only. FLS: http://merck.us/3TKXNuZ

Industry: Pharmaceutical Manufacturing
Company Size: 10,001+ employees

Merck

**Job Description**

The Cardiometabolic Disease (CMD) department at our company's Research Labs in South San Francisco is seeking a Senior Scientist to join our discovery team. This role offers an exciting opportunity to contribute to cardiovascular drug discovery by developing and applying robust cell-based and ex-vivo systems to advance understanding of disease biology and mechanism of action.

The successful candidate will demonstrate strong initiative, operating in a multidisciplinary, matrixed environment to identify, mechanistically validate, and advance novel therapeutic targets for cardiovascular disease. This role is well suited for an intellectually curious and driven scientist with a hypothesis-focused mindset who excels at integrating in vitro findings with preclinical in vivo and human-relevant insights to inform discovery-stage decisions.

**Key Responsibilities**

- Independently design, optimize, and execute cell-based and ex-vivo assays to interrogate disease pathways and pharmacologic mechanisms.

- Lead mechanism-of-action studies using molecular, biochemical, and cellular approaches to link target modulation to disease biology.

- Generate high-quality, reproducible data and apply critical analysis to guide decision-making and prioritization.

- Collaborate effectively with cross-functional teams to advance cardiovascular drug discovery programs.

- Incorporate emerging assay technologies to strengthen discovery capabilities.

- Stay current with scientific advances in cardiovascular and translational biology.

- Communicate scientific rationale, assay strategies, and key findings clearly to diverse audiences.

- Maintain rigorous documentation in electronic lab notebooks and contribute to presentations, technical reports, and manuscripts.

**Education**

**QUALIFICATIONS:**

- Master's (with 4+ years) or Ph.D. (with 1+ years) in physiology, pharmacology, biomedical sciences or related field and relevant drug discovery experience.

**Required Experience And Skills**

- Demonstrated expertise in designing, executing, and interpreting in vitro and ex-vivo experiments with high scientific rigor.

- Proven ability to independently drive experiments, troubleshoot assays, and derive actionable conclusions.

- Demonstrated creativity and problem-solving ability in addressing complex biological questions using state-of-the-art in vitro approaches (reflected by publications and/or impactful internal contributions).

- Proficiency in standard molecular, cellular, and biochemical techniques.

- Strong quantitative skills, including data analysis and application of statistical approaches to biological datasets.

- Excellent communication and organizational skills, with the ability to manage multiple projects in a matrixed environment.

**Preferred Experience And Skills**

- Experience with primary or advanced cell culture systems (including 2D and 3D models) in cardiac or vascular biology.

- Strategic thinker with a background in one or more relevant areas (atherosclerosis, heart failure, inflammation, renal disease, lipid metabolism).

- Solid understanding of the translational strengths and limitations of in vitro models.

- Experience developing fit-for-purpose in vitro assays to support compound profiling and mechanism-based evaluation.

- Familiarity with multi-omics approaches (e.g., single-cell RNA-seq and proteomics) to support target biology and validation.

- Understanding of in vivo cardiovascular models and physiological endpoints.

#EligibleforERP

**Required Skills**

Cardiometabolic, Cell Cultures, Ex Vivo Assays, In Vitro Assays, In Vitro Models, In Vitro Studies, Vascular Biology

**Preferred Skills**

Current Employees apply HERE

Current Contingent Workers apply HERE

**US And Puerto Rico Residents Only**

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

**Requirements**

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

The salary range for this role is

$131,400.00 - $206,800.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

**San Francisco Residents Only: ** We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

**Los Angeles Residents Only: ** We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

**Search Firm Representatives Please Read Carefully**

Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

**Employee Status**

Regular

**Relocation:**

Domestic/International

**VISA Sponsorship**

Yes

**Travel Requirements**

No Travel Required

**Flexible Work Arrangements**

Not Applicable

**Shift**

1st - Day

**Valid Driving License**

No

**Hazardous Material(s)**

N/A

**Job Posting End Date**

06/2/2026

- A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

**Requisition ID: **R398471

Senior Scientist, In Vitro (Cardiometabolic Disease)

AbbVie is a global biopharmaceutical company focused on creating medicines and solutions that put impact first — for patients, communities, and our world. We aim to address complex health issues and enhance people's lives through our core therapeutic areas: immunology, oncology, neuroscience, eye care, aesthetics and other areas of unmet need.  

Learn more about us at www.abbvie.com and review our community guidelines at https://www.abbvie.com/social-media-community-guidelines.html.

Industry: Pharmaceutical Manufacturing
Company Size: 10,001+ employees

AbbVie

**Company Description**

**About AbbVie**

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.

**Job Description**

We are looking for an experienced and versatile Senior Scientist II/Mechanical Engineer to join our Injection Device Development team to help us accelerate AbbVie’s combination products from proof-of-concept through submission, industrialization and launch.

Our team has end-to-end accountability for commercial development, submission, industrialization and marketed product support for injection devices that enable the delivery of AbbVie’s innovative medicines. In the course of our work, we collaborate with early-stage CMC, Quality Assurance, Regulatory Affairs, Internal and External Manufacturing, and other cross-functional colleagues to ensure timeliness, robustness and market success.

As a Principal Research Scientist I at AbbVie you will be part of a multi-disciplinary team of professionals working at the intersection of engineering and biopharmaceuticals. The problems you would help to solve relate not only to the function of innovative injection systems, but also the way in which they interact with drug products and the human body. You would be responsible for advancing programs that combine proven delivery systems with viable commercial drug assets. If you are a self-motivated person who thrives on solving complex problems and are excited by the idea of putting life-changing therapies in the hands of patients, this might be the opportunity for you.

**Responsibilities**

- Create and maintain product design documentation

- Lead design transfer and industrialization activities

- Initiate and lead product design changes and continuous improvement effort

- Design and execute laboratory studies supporting product development and on-market investigations

- Conduct analytical modeling of key performance attributes of designs

- Perform 3D and 2D CAD development in PDM environment

- Protocol development, documentation of results and authoring of summary reports

- Collaborating with third party developers and suppliers

- Mentor/supervise a team of one or more and evaluate the performance of those individuals; is accountable for the effective performance of the team/individuals

**Qualifications**

- BS in Mechanical or Biomedical Engineering (MS preferred, PhD aspirational)

- 14+ years of experience (MS 12+ years, PhD 6+ years) ideally in the medical device, drug delivery or other regulated industry

- Demonstrated ability to function as a principle investigator, generating original technical ideas and research or development strategies.

- Demonstrate creative 'out of the box' thinking to solve difficult technical problems and champion new technologies to achieve project goals

- Experience with: Design controls (in accordance with ISO 13485 / CFR 820.30), high volume manufacturing processes, 3D CAD modeling, detailed engineering drawings, product database management environment and GD&T, laboratory environment, experiment planning, material control and recordkeeping, technical protocol and report writing, statistical analysis, physical prototyping (including 3D printing, manual machining, etc.), toolroom environment

- Knowledge of material properties, material selection and testing methodologies

- The ability to create and manage schedules for sub-tasks and work streams

-  A keen eye for identifying project risks and proactively developing mitigation plans

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

- The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of thisposting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location,and we may ultimately pay more or less than the posted range. This range may be modified in the future.

- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.

- This job is eligible to participate in our long-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission,incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless anduntil paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

Senior Scientist II/Mechanical Engineer

Bruker Life Science Mass Spectrometry is a leading global developer and manufacturer of innovative scientific instruments that address the rapidly evolving needs of a diverse array of life sciences customers. Our mass spectrometry-based tools serve the pharmaceutical, biotechnology, molecular diagnostics research and chemical analysis industries. Bruker's analytical instruments deliver exceptional high-resolution results for pre-clinical and clinical testing.  Research institutes, universities and government agencies routinely turn to Bruker for systems that address real world needs.

Innovations such as Trapped Ion Mobility (TIMS), smartbeam and scanning lasers for MALDI-MS Imaging that deliver true pixel fidelity, and eXtreme Resolution FTMS (XR) technology capable to reveal Isotopic Fine Structure (IFS) signatures are pushing scientific exploration to new heights. Our mass spectrometry solutions enable scientists to make breakthrough discoveries and gain deeper insights.

Bruker's product lines include the following technologies: timsTOF, MRMS, rapifleX® MALDI-TOF/TOF, UHR-QTOF, Triple Quadrupole, HDX Solution, Toxtyper® and TargetScreener HR. Our industry leading software solutions such as SCiLS™ Lab for MS Imaging, MetaboScape® and Biopharma Compass® are examples for our solutions doing the work for you.

(For Research Use Only. Not for use in clinical diagnostic procedures)

Industry: Biotechnology Research
Company Size: 1,001-5,000 employees

Bruker Daltonics

Bruker is one of the world’s leading analytical instrumentation companies enabling scientist to make breakthrough discoveries and develop new application that improve the quality of human life. Our high-performance products and high-value life science and diagnostic solutions are trusted by leading businesses, institutes, and scientists worldwide. Today, more than 11,000 employees at over 90 locations are working on this permanent challenge to make the world a better place.

Bruker Spatial Genomics (BSG, a Bruker subsidiary) is focused on opening a new frontier in spatial 3D genomics and multiomic analyses. We are committed to the development of a novel technology platform allowing progress in genome-wide visualization of spatially resolved 3D chromosome and chromatin architecture in individual cells and cell populations in situ. We bring together the premier spatial omics approach, jebFISHTM, with leading-edge imaging, data acquisition and analysis capability.

Our pioneering in situ technology enables examination of some of the most important questions in genomics and gene expression at the single cell and sub-cellular level. We aim to find the best talent in the field to join and contribute to this extraordinary endeavor, becoming a critical member of this groundbreaking opportunity.

Bruker Spatial Genomics Is Looking For a Staff Scientist For Their R&D Team. The Position And Ideal Candidate Is Described As Follows

-  The candidate will be a key contributor to optimization and development of advanced bioassays for determination of chromosome and chromatin architecture through the use of spatial omics approaches.

-  This is a unique multi-disciplinary position that will work closely with a variety of disciplines including scientists and engineers with molecular biology, general wet lab, or imaging experience. As part of our team, you will design and conduct cutting edge approaches and experiments to map spatial gene activity and expression and develop new technologies for multiomic integration. You will conceptualize and oversee technique invention, optimization, and transfer of the leading approach to in situ imaging of gene activity, localization, and expression in diverse tissue (FF and FFPE) and cell types.

-  The ideal candidate should have demonstrated wet lab experience working independently in a biophysics, chemistry, biochemistry, or molecular biology laboratory, have exceptional attention to detail, be creative, and be able to critically analyze data and communicate results to the team. This position must be able to independently make decisions on work direction.

-  They should be enthusiastic to work as part of a team in a fast-paced startup environment, and must bring a can-do attitude and sense of purpose to the job.

**Responsibilities**

-  Support and spearhead the method development and optimization of novel molecular biology assay schemes for spatial omic applications including molecular barcoding, fluorophore marking, nucleic acid hybridization, amplification and sequencing techniques, and probe library preparation.

-  Support the optimization of probe chemistry and probe-based sequencing with spatial multi-omic profiling applications.

-  Help develop the optimization of sample preparation methods such as tissue/cell fixation and permeabilization in diverse tissue (FF and FFPE) and cell types.

-  Independently plan and execute experiments, accurately record details, provide in-depth analysis, and report results through documentation and presentations.

-  Assist/lead in the analysis of large and complex data sets, including developing routines for streamlined and automated data pipelines.

-  Prepare assay reagents and other components.

-  Work within multidisciplinary teams at all stages of product development.

-  Assist with research projects to profile spatial genomics. Collaborate with other team members on research studies.

-  Support and lead elements of the development, verification and validation of product related kits and reagents.

-  Analyze specimens on imaging instrumentation. Analyze research data and assist with data interpretation.

-  Interface directly with product development teams to transfer and optimize new technologies.

-  Prepare research reports and share findings with the team. Write protocols, develop procedures, and maintain accurate records.

-  Clearly communicate and present results; contribute data for making critical design decisions.

**Qualifications**

Educational/Experience requirements:

- PhD in biophysics, chemical/biomolecular engineering, molecular biology, biochemistry, cell biology, or a related field and 5+ years of hands-on molecular biology experience in an industrial setting.

- Proficient in standard molecular biology techniques such as sample preparation, nucleic acid amplification and purification (RNA/DNA), qPCR, and DNA sequencing or similar molecular biology techniques. Experience with applying microscopy to answer biological problems.

- Knowledge of advanced fluorescence in situ hybridization (FISH) or other in situ fluorescence probed-based techniques. Understanding of basic absorption and emission spectroscopy.

- Highly motivated with excellent attention to detail. Good communication (oral and written) and collaboration skills.

- Experience in cell culture and tissue (FF and FFPE) preparation techniques.

- Experience in troubleshooting and optimization of molecular biology assays including reagent formulation and workflow optimization.

- Experience with experimental design and data analysis. Must be capable of performing complex multi-step experiments with detailed and diligent attention to technique and protocols with accurate record keeping.

- Desire to be part of a rapidly evolving organization, which requires real-time communication, flexibility, working well with others, and a willingness to learn new techniques and methods.

**Additional Desirable Skills**

- Experience with multiplexed, multiomic imaging technologies in tissues and cells.

- Experience in product development including product release.

- Familiarity with basic statistical data and error analysis. Familiarity with single cell and/or spatial transcriptomics, fixation chemistry, Design of Experiments (DOE).

- Advanced fluorescence imaging techniques. Experience in microscopy image analysis.

- Familiarity with different cell and tissue segmentation software and programs

- Experience with use and troubleshooting of automated equipment, preferably for imaging applications.

At Bruker, base salary is part of our total compensation. The estimated base salary range for this full-time position is between $99,450 and $177,000 provides an opportunity to progress as you grow and develop within a role. The base salary for the role will depend on a several job-related factors, including, but not limited to education, training, experience, the geographic location of the successful candidate, skills, competencies, job-related knowledge and travel requirements for this position. Full-time employees may also be eligible for a performance-related incentive in addition to a full range of benefits including 401(k) with company match, an employee stock purchase plan, medical and dental plans, life insurance, short-term and long-term disability insurance, employee assistance program and paid time off including vacation, sick time and holidays, and more.

Bruker is an equal-opportunity employer. We evaluate qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, and

other legally protected characteristics.

Certain positions at Bruker require compliance with export control laws and as a result, all interviewed candidates for all positions will be screened pre-interview to determine their eligibility in light of export control restrictions

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