At Merck, known as MSD outside of the United States and Canada, we are unified around our purpose: We use the power of leading-edge science to save and improve lives around the world. For more than 130 years, we have brought hope to humanity through the development of important medicines and vaccines. We aspire to be the premier research-intensive biopharmaceutical company in the world – and today, we are at the forefront of research to deliver innovative health solutions that advance the prevention and treatment of diseases in people and animals. We foster a diverse and inclusive global workforce and operate responsibly every day to enable a safe, sustainable and healthy future for all people and communities. For more information, visit www.merck.com. 

This site is intended for residents of the United States and Canada and their territories only. FLS: http://merck.us/3TKXNuZ

Industry: Pharmaceutical Manufacturing
Company Size: 10,001+ employees

Merck

Savvy Admin PROD

**Job Description**

The **Senior Director (Sr. Principal Scientist) ** has primary responsibility for the strategic planning and directing clinical research activities involving investigational compounds in Immunology. With a focus on late-stage development, the Senior Clinical Director will manage the entire cycle of clinical development, including determination of appropriate disease indications to pursue and subsequent study design, initiation, execution, monitoring, analysis, regulatory filing, and publication.

**Specifically, The Senior Director May Be Responsible For**

- Evaluating pre-clinical and translational work for the purpose of generating the early clinical development plan and Investigational New Drug applications.

- Providing clinical development support of business development assessments of external opportunities to grow the Immunology Pipeline

- Developing clinical development strategies for investigational drugs and planning clinical trials (design, operational plans, settings) based on these clinical development strategies.

- Monitoring and managing the conduct of ongoing or new clinical trials for investigational drugs.

- Analyzing and summarizing the clinical findings from studies to support decisions regarding safety and efficacy as well as new drug applications, clinical study reports, or publication; and

- Participation in internal and joint internal/external research project teams relevant to the development of new compounds

**The Senior Director May**

Supervise the activities of Clinical Scientists in the execution of clinical studies. Work closely with a cross-functional group of experts in commercialization, regulatory affairs, statistics, and manufacturing to manage clinical development projects; and assist the Executive Director in ensuring that appropriate Corporate personnel is informed of the progress of studies of our company and competitors' drugs and internal and external expert opinion on scientific questions relevant to his/her areas of responsibility.

The Senior Director is responsible for maintaining a strong scientific fund of knowledge by:

- Maintaining awareness of scientific developments within his/her area of expertise, in terms of new scientific findings, research methodologies

- Identification of scientifically and operationally strong investigators who can assist in the development of our company's investigational drugs in Immunology.

- Establishing collaborative relationships with external experts in Rheumatology, Gastroenterology, Dermatology, Pulmonary, or rare diseases, particularly those whose research focus and expertise can inform and assist the evaluation of the company's investigational drugs.

- Attending appropriate scientific meetings to maintain his or her competency and to maintain awareness of research activities in his/her area of responsibility.

**To Accomplish These Goals, The Senior Director May**

- Author detailed development documents, presentations, budgets, and position papers for internal and external audiences.

- Facilitate collaborations with external researchers around the world.

- Travel on company business about twenty (20) percent of the time to manage future or ongoing clinical research projects.

**Qualifications**

**Education minimum required:**

M.D., D.O., M.D./Ph.D, or D.O./PhD..

**Required Experience And Skills**

- Experience in the design and/or execution of phase 2 or 3 clinical trials specifically in Immunology

- Minimum of 3 years of clinical medicine experience

- Minimum of 5 years of industry experience in drug development

- Demonstrated record of scientific scholarship and achievement

- Strong interpersonal skills, as well as the ability to work collaboratively in a cross-functional team environment.

**Required Skills**

Clinical Development, Clinical Documentation, Clinical Immunology, Clinical Judgment, Clinical Medicine, Clinical Research Management, Clinical Sciences, Clinical Studies, Clinical Trial Development, Data Analysis, Drug Development, Hiring, Ophthalmology, Rare Diseases, Scientific Consulting, Strategic Planning

**Preferred Skills**

Current Employees apply HERE

Current Contingent Workers apply HERE

**US And Puerto Rico Residents Only**

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

**Requirements**

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

**U.S. Hybrid Work Model**

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.

The salary range for this role is

$282,200.00 - $444,200.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

**San Francisco Residents Only: ** We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

**Los Angeles Residents Only: ** We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

**Search Firm Representatives Please Read Carefully**

Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

**Employee Status**

Regular

**Relocation:**

**VISA Sponsorship**

**Travel Requirements:**

**Flexible Work Arrangements**

Hybrid

**Shift**

**Valid Driving License:**

**Hazardous Material(s)**

**Job Posting End Date:**

04/23/2026

- A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

**Requisition ID: **R389095

Senior Principal Scientist, Clinical Research, Immunology - Ophthalmology

Geosyntec is a consulting and engineering firm that works with private and public sector clients to address new ventures and complex problems involving our environment, natural resources, and civil infrastructure.

Industry: Environmental Services
Company Size: 1,001-5,000 employees

Geosyntec Consultants

**Overview**

If you’re looking for a place to advance your career, where you can contribute to a dynamic innovative firm, tackle demanding project work, and collaborate with industry recognized professionals – Geosyntec Consultants is the place for you!

**Geosyntec ** is seeking a Principal level **Water Resources Market Leader ** to join our growing national Water Resources Practice, based out of our **Los Angeles, CA ****; ** **San Diego, CA; ** **Sacramento, CA; **or any of our other U.S. based offices. The potential to work remotely from your home-office is available at the discretion of the Company. This is a unique opportunity to join a leadership team actively engaged in growing the water business at Geosyntec. This position will be responsible for developing and implementing a strategy for achieving significant market share for Geosyntec in the Water Resources market area.

As a senior member of our Water Resources practice, you lead complex water resources projects around water supply management, water rights permitting, and groundwater / surface water management. As a market leader, you will be responsible for a combination of technical project execution, client relationship management and water resource subject matter expertise, task and team leadership, while actively engaging existing and new client opportunities from a business development growth standpoint. Our Water Resources group works on complex projects ranging from water supply development, water supply management, water rights, mining hydrogeology, contaminant hydrogeology, regulatory permitting, and source water protection, across the U.S.; In this role, you will have the opportunity to build and lead a team of experienced professionals, contribute to complex technical project work, as well as actively engage in growth and business development strategy.

Geosyntec is an innovative, international engineering and consulting firm serving private and public-sector clients to address new ventures and complex problems involving our environment, natural resources, and civil infrastructure. Our engineers, scientists, technical and project employees serve our clients from offices across the world. Ranked by ENR as one of the top environmental engineering design firms, Geosyntec is internationally known for its technical leadership, broad experience, and exceptional client service.

We invest in our people. Each employee is unique, and your career at Geosyntec will be too. We offer competitive pay and benefits, and well-being programs to support you and your family.

To Learn More Visit: http://www.geosyntec.com/careers/ .

**Essential Duties And Responsibilities**

-  Strategic business planning to segment and target specific industrial, commercial and municipal clients for projects such as water supply, groundwater and surface water modeling, water availability, use and re-use, as well as regulatory considerations for water rights permitting; focused on the West Region Water Resources market;

-  Engagement with project and operations staff to align Geosyntec’s full service delivery capabilities with market demands;

-  Serve in the capacity of a Client Account Manager on selected accounts deemed critical to Geosyntec’s Water Resources market;

-  Active participation in professional societies, conferences, and meetings that will increase the visibility of the firm to potential clients and recruits. Make contributions to the profession that will result in individual recognition as an industry leader;

-  Project directorship, including ensuring client expectations are understood and met, budgets are adhered to, quality objectives are met, and follow-on work is attainted – Strategically related to; local scale hydrogeologic analyses for water supply management, regulatory compliance and new source development; modeling studies of aquifer systems; installation and testing of groundwater supply wells (and monitoring wells), aquifer storage and recovery (ASR) and surface recharge basin projects, and permitting and regulatory compliance projects, including water rights;

-  Recruiting, managing, and mentoring junior staff and mid-career engineers and scientists;

-  Reviewing and leading the preparation of major proposals;

-  Providing senior leadership subject matter expertise in meetings with clients, regulatory personnel, and other parties;

-  Technical Project delivery and project-manager responsibility for scoping, performing, managing, and delivering multiple concurrent project assignments;

-  Preparing technical reports, letters, memoranda, plans, specifications, and proposals

-  Drive personal, company, and rental vehicles to client or company project or office sites, and other business locations, as needed.

**Education and Licensure**

-  Bachelor's degree in Water Resources, Hydrogeology, Civil, Environmental or related engineering discipline with emphasis on water resources. (required)

-  Advanced degree in the same/similar (preferred)

-  Professional registration (i.e., PE, CHG) (required)

**Skills, Experience And Qualifications**

-  At least 10 years (15+ preferred) of direct water resources, hydrogeology, or engineering consulting experience working on water resource, contaminated sites, and mining projects; or equivalent combination of education and experience. (required)

-  Experience with multi-disciplinary project teams. (required)

-  Demonstrated success in project management, sales, and business development. (required)

-  Excellent leadership and detail-orientation skills. (required)

-  Experience with design and implementation of field hydrogeology programs in glacial, basalt, and clastic aquifer systems (required)

-  Experience with numerical modeling of groundwater flow and well test analysis (preferred).

-  Ability and willingness to perform fieldwork and travel as needed. (required)

-  Health & Safety training, medical monitoring, and client-driven drug and background testing may be required.

-  Valid U.S. driver’s license and a satisfactory driving record for business travel. (required)

This opportunity will be posted for at least five days. Below are the potential compensation ranges that we in good faith believe are applicable for this role at the time of this posting and are only applicable for jobs to be performed in the specified location(s) below. The typical base salary range for this position is just one component of Geosyntec’s total compensation package for employees. Actual compensation will be determined based on education, experience, skill set and location.

-  Minimum Salary: $149,330 /year / Maximum Salary: $259,690 /year (San Diego, CA, Sacramento, CA)

-  Minimum Salary: $156,115 /year / Maximum Salary: $271,495 /year (Los Angeles, CA)

We offer a comprehensive benefits package including, paid holidays, vacation, sick, and personal paid time off, medical, dental, vision, life, and disability insurance, 401(k), and other benefits to eligible employees.

Water Resources Market Leader

We’re an integrated photonics company in California building the light engines that power the next era of quantum technology — from advanced computing to precision sensing.

Industry: Computers and Electronics Manufacturing
Company Size: 51-200 employees

Monarch Quantum

Join our fast-paced and passionate team as a Principal Optical Engineer. As we scale, you will be instrumental in building our foundation from the ground up. This is a dynamic, hands-on role for a self-starter who thrives in a fluid startup environment. You'll have the opportunity to work on cutting edge technologies, work closely with leadership, and develop and implement engineering practices that support our mission and growth. Your key responsibilities are as follows:

- Work independently and in a team while overcommunicating with the manager, project engineer, and teammates.

- Execute complex engineering tasks involving planning, preparation, data/information collection, and analysis and decision-making in a process involving peer reviews and documentation of the results.

- Use tenacity, patience, self-discipline, and passion for excellence to assure accuracy of execution schedule, data quality/integrity, conformance to company best practices, clarity in communication, and documentation

- Use every opportunity to grow competency through mentorship, curiosity, communication, exposure, and initiative

- Drive innovation in modeling, design, analysis, and alignment methods to support product roadmap

- Support project engineering with project scope, schedule, and risk analysis

**Requirements**

- This position requires access to export-controlled information. Employment is contingent upon the applicant being a U.S. person as defined by 8 U.S.C. § 1324b(a)(3)

**Experience: **

- A bachelor's degree in Optical Engineering, Physics, or a related field

- Minimum of 9 years of relevant experience, ideally within a startup or technology company

**Skills: **

- Deep understanding of laser beam propagation: how optic movement and rotation impact a beam's near-field, far-field, beam quality, and fiber coupling efficiency

- Fluency applying ray-equivalent methods of laser propagation to guide architecture and debug layout questions

- Fluency determining the best way to answer a design problem, including combinations of design software, macros, external code, and manual calculations

- Ability to use paraxial raytracing and ABCD matrices to derive analytical expressions for trends, sensitivities, and scaling factors in various optical layouts

- Fluency in applying first-order imaging and the overlap integral of Gaussian beams to interrogate the design space of a laser module

- Understanding of how component properties impact alignment sensitivity (e.g. collimation lens focal length)

- Ability to take a novel optical design question, distill it to an algebraic method, and validate the analysis using a second calculation method (e.g. optical design software).

- Ability to turn exotic optical requirements into concrete analysis tasks (e.g. acousto-optic modulator RF tuning range, impact of thermal lensing)

- Fluency in applying first-order imaging and the overlap integral of Gaussian beams to derive component fabrication and alignment requirements

- Ability to derive quantitative requirements for optic prescriptions (surface roughness, scratch/dig, surface power, surface irregularity, aspheric sag error, material properties)

- Understanding of different tolerancing methods for conventionally polished, sub-aperture polished, and precision glass molded components

- Ability to engage vendors to understand capabilities and drive clarity to get quotes for components, accounting for supplier yield, risk, and schedule

- Understanding of optical metrology methods and how to specify a drawing congruent with a vendor's measurement facilities

- Fluency creating efficient layout optimization workflows in non-sequential design software for nontrivial architectures

- Understanding of polarization ray tracing and how to analyze polarization through optic trains with dozens of surfaces

- Understanding of polarization components within both Jones and Mueller models

- Deep understanding of fiber optics for high power CW laser systems: multi-mode, single mode, polarization maintaining, step index, photonic crystal, endcaps

- Understanding of stray light analysis in the context of a laser system

- Demonstrated successful execution of engineering tasks including use of design software (Ansys Zemax OpticStudio, Photon Engineering FRED, and/or Lambda Research OSLO preferred) and quantitative analysis/programming tools (Python), instrumentation and measurement, part fabrication or procurement, integration and test, data collection, and documentation

**Startup Mindset: **

- You're creative, flexible, and eager to wear multiple hats.

- You're passionate about building systems from the ground up and comfortable with ambiguity and change

**Benefits**

The expected annual salary range for this position is $150,000-$200,000.

As a full-time employee, you will be eligible for Monarch's comprehensive benefits package, which includes:

- Medical, Dental, and Vision insurance

- Fidelity 401(k) plan with 4% employer matching

- 20 paid time off (PTO) days per year

- 13 paid company holidays

- 9/80 work schedule (every other Friday off)

Monarch Quantum is proud to be an equal opportunity employer and does not discriminate on the basis of race, color, citizenship status, national origin, ancestry, sex, sexual orientation, age, religion, creed, physical or mental disability, medical condition, marital status, veteran status or any other characteristics protected under applicable federal, state and local laws.

Optical Engineer Level 4

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