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Industry: Internet News
Company Size: 11-50 employees

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**Company Description**

**About AbbVie**

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube.

**Job Description**

The AbbVie Process Chemistry Chromatographic Separations Lab is actively seeking an Associate Scientist II or Scientist I. Our team collaborates with colleagues across multiple disciplines, offering expertise in preparative chromatography to support a broad range of AbbVie R&D programs. We maintain and utilize specialized equipment for various separation tasks, including the purification of peptides, ADC drug-linkers, and chiral compounds, as well as the isolation of low-level API impurities. Additionally, the team is responsible for pilot-scale preparative purification, developing scalable purification processes, and overseeing their implementation under cGMP guidelines at AbbVie's North Chicago Chemical Pilot Plant. This role will contribute to the development of novel/advanced separations technologies and broader efforts to develop new process technologies for advancing the AbbVie pipeline.

We are seeking a motivated scientist who demonstrates initiative and technical proficiency in supporting research and development projects within a collaborative team environment. The ideal candidate will have hands-on experience developing chromatographic methods and troubleshooting complex separation challenges. Experience working with peptides is highly desirable, but not required for application.

**Key Responsibilities**

- Develop and execute purification processes supporting development of small molecule, antibody drug conjugate, and peptide clinical candidates.

- Demonstrate scientific initiative and creativity in planning, executing, and troubleshooting experiments, resolving key project challenges with an appropriate level of autonomy based on experience.

- Conduct a range of laboratory and pilot-scale tasks, analyze and interpret data, and drive project objectives, assuming responsibility for tasks in accordance with experience.

- Suggest, adapt, and, as appropriate, implement new or improved experimental protocols/techniques, consulting relevant literature as needed.

- Build and maintain strong collaborative relationships with peers and cross-functional partners.

- Foster a learning environment, encourage diverse ideas, and support continuous process improvement.

- Understand and adhere strictly to corporate standards for conduct, safety, quality, and proper handling of materials.

**Qualifications**

- Bachelors degree with at least 3 years (Associate Scientist II) or 5 years (Scientist I) relevant experience; or Masters degree with no additional experience (Associate Scientist II) or typically +2 years of relevant experience (Scientist I).

- Strong technical background in Separations Science, with theoretical and practical knowledge required to independently carry out job functions.

- Demonstrated proficiency in developing, troubleshooting, and modifying chromatographic methods and purification protocols.

- Broad expertise in analytical techniques, with emphasis on chromatography, compound purification, and spectral analysis.

- Ability to search scientific literature and evaluate potential solutions to research problems.

- Effective written and oral communication skills; able to work collaboratively in multidisciplinary teams.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

- The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at thetimeofthis posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographiclocation,andwemay ultimatelypay more or less than the posted range. This range may be modified in thefuture.

- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.

- This job is eligible to participate in our short-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.Theamountandavailabilityof anybonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company'ssoleandabsolutediscretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

Associate Scientist II, Process Chemistry Separations

**Company Description**

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onX,Facebook,Instagram,YouTube,LinkedInandTik Tok.

**Job Description**

Process Engineering, a part of AbbVie R&Ds Development Sciences organization, is responsible for designing and developing scalable processes to make drug substances and drug products, including small molecules and antibody drug conjugates (ADCs), throughout pre-clinical and clinical development stages. Process Engineering also partners with Biologics CMC (Chemistry, Manufacturing, and Controls) Development and Aesthetics R&D functions to provide active engineering support to enable robust process scale-up and manufacturing of biologics drug substances and drug products including toxins and cosmetic active ingredients (CAIs). We contribute to the development of innovative engineering technologies and create valuable intellectual property through the composition of matter, chemical processes, and technologies resulting in cost-effective commercial manufacturing processes. We support the development of the supply chain for pipeline molecules and help prepare and defend CMC regulatory content.

Chemical/Bio Engineers within Process Engineering support pipeline projects through all phases of development. Early in development, engineers focus on establishing an enabling process that can be scaled-up successfully. In the later stages of development, engineers optimize the drug substance and drug product processes and lead manufacturing campaigns. Engineers also work cross-functionally to transfer the optimized process to manufacturing sites, develop control strategy, and prepare reports to support regulatory filings.

**Role Overview**

The successful engineering candidate will play a key role in the R&D Process Engineering function.The core deliverable of R&D Process Engineering is to develop robust manufacturing processes and advance innovative technologies using strong engineering fundamentals. The ideal candidate will have prior biologics, peptide, or ADC development experience and a passion for hands-on laboratory process development. The candidate is also expected to lead the identification and development of novel approaches and technologies to enhance process development efficiency and commercialization. The candidate must exhibit a collaborative nature in identifying process challenges on a wide range of projects, take part in a cross-functional team to deliver specific project needs, and take on a leadership role in developing and implementing solutions.

**Key Responsibilities**

- Develop robust manufacturing processes, supporting assets through all phases of development.

- Participate in and/or lead project teams towards development and characterization of new small and large molecule assets. Establish, communicate, and execute research plans.

- Develop commercial ready manufacturing processes in the laboratory and demonstrate the processes in the pilot plant.

- Set project strategies, define project responsibilities and timelines, and provide leadership in a matrixed team setting.

- Addresschallenging problems with biochemical reactions, separations, and/or isolations using expertise in reaction kinetics, transport phenomena, and mathematical modeling.

- Author and/or review technical documents summarizing process development efforts and contribute to regulatory filings.

- Exhibita collaborative nature in identifying process challenges on a wide range of projects and communicate findings and recommendations effectivelyby multi-disciplinary interactions with organic chemists, analytical chemists, process development engineers, pilot plant engineers, drug product development scientists, program managers, and regulatory affairs specialists.

- Author publications and present at scientific conferences.

**Qualifications**

- BS, MS, or PhD in Chemical/Bio Engineering or a related field and 14+ (BS), 12+ (MS), or 6+ (PhD) years of relevant industrial experience.

- Ph.D. candidates with pertinent research exposure are also encouraged to apply.

- Job level will be commensurate with academic and/or industrial work experience.

- Candidates are expected to have a strong background in chemical engineering and the proven ability to demonstrate their skills in this field.

- The candidate is expected to demonstrate the ability to solve difficult technical problems and champion new technologies to achieve project goals.

- The candidate is required to be a strong team player and demonstrate scientific leadership, possessing effective oral and written communication skills for facilitating collaborations and leading cross-functional process development teams.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

- The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this postingbased on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemay ultimatelypaymore or less than the posted range. This range may be modified in thefuture.

- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.

- This job is eligible to participate in our short-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission,incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company's sole andabsolutediscretion unless and untilpaid andmay be modified at the Companys sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

Principal Research Scientist I, Process Engineering

**Company Description**

**About AbbVie**

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube.

R&D Process Engineering Organization, a part of AbbVies Development Sciences organization, is responsible for designing and developing scalable processes to make drug substances and drug products, including synthetics molecules, antibody drug conjugates (ADCs) and genetic medicines, throughout pre-clinical and clinical development stages. Process Engineering also partners with Biologics CMC (Chemistry, Manufacturing, and Controls) Development and Aesthetics R&D functions to provide active engineering support to enable robust process scale-up and manufacturing of biologics drug substances and drug products including toxins and cosmetic active ingredients (CAIs). It drives the development of innovative engineering technologies and creates valuable intellectual property through the composition of matter and chemical/bio-chemical processes resulting in cost-effective commercial manufacturing processes for quality products. Process Engineering organization also supports the scale-up in the pilot plants and supply chain development for pipeline molecules and supports the justification of CMC regulatory content.

**Job Description**

**Role Overview**

The successful Process Engineering candidate will play a key technical team leader role in the R&D Process Engineering function.In addition to a strong background in fundamentals of chemical engineering, the ideal candidate will have demonstrated experience in the biologics, peptides, ADC development and genetic medicines as a strong technical team leader. The candidate must have demonstrated initiative in building and sustaining cross-functional collaborations.In addition to leading the technical team, the successful candidate is also expected to lead the identification and development of novel approaches and technologies to enhance process development efficiency and commercialization of novel modalities. The candidate must exhibit a collaborative behavior in proactively identifying process challenges on a wide range of pipeline and innovation projects, take a leadership role in a cross-functional team to deliver specific project needs, and take on a scientific leadership role in developing and implementing solutions.

**Key Responsibilities**

- Develop robust manufacturing processes, supporting assets including novel modalities through all phases of clinical development.

- Lead project teams towards process development and characterization of new synthetic and large molecule assets.

- Influence process development of toxins, cosmetic active ingredients and genetic medicines proactively.

- Lead scale-up of laboratory processes in the pilot plant.

- Set project strategies, define project responsibilities and timelines, and provide leadership in a matrixed team setting.

- Addresschallenging problems with biochemical reactions, separations, and/or isolations using expertise in reaction kinetics, transport phenomena, and mathematical modeling.

- Establish, communicate, and execute research plans.

- Exhibita collaborative nature in identifying process challenges on a wide range of projects and communicate findings and recommendations effectivelyby multi-disciplinary interactions with organic chemists, analytical chemists, process development engineers, pilot plant engineers, drug product development scientists, program managers, and regulatory affairs specialists.

- Author and/or review technical documents summarizing process development efforts and contribute to regulatory filings.

- Strengthen scientific brand of Process Engineering while providing mentorship to direct reports and process engineering colleagues.

**Qualifications**

- BS, MS, or PhD in Chemical/Bio Engineering or a related field and 18+ (BS), 16+ (MS), or 10+ (PhD) years of relevant biopharmaceuticals industrial experience.

- Ph.D. candidates with pertinent research exposure are also encouraged to apply.

- Job level will be commensurate with academic and/or industrial work experience.

- Candidates are expected to have a strong foundations in chemical engineering and the proven ability to demonstrate their skills in this field.

- The candidate is expected to demonstrate the ability to solve challenging technical problems and champion next generation of innovative technologies to achieve project goals around novel modalities.

- The candidate is required to be a strong team player and demonstrate scientific leadership, possessing effective oral and written communication skills for facilitating co-creation and leading cross-functional process development teams.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

- The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this postingbased on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemay ultimatelypay more orless than the posted range. This range may be modified in thefuture.

- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.

- This job is eligible to participate in our short-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission,incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company's sole andabsolutediscretion unless and until paidandmay be modified at the Companys sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

Senior Principal Research Scientist Engineering

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