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Industry: Internet News
Company Size: 11-50 employees

BioSpace

Savvy Admin PROD

**Company Description**

**About AbbVie**

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube.

**Job Description**

AbbVie Discovery Neuroscienceteamseeksacollaborativesenior scientistwho willlead fromthe laboratory benchto support advancement of psychiatry assets.In this onsite role,youwillleverageyoursignificant demonstrated experience inmolecular and cellular pharmacology,in vitrohuman-derivedcellular models, and ex vivo sample analysistopropose/evaluatenew approachesandcarry outwell-matched approachesfor scientific questionssupporting advancement of assets through stage-gate transitions.

You will be expected tohavestrong communicationskills,be agile,operatecomfortably with ambiguity on formal and informal teams, and workwith a sense of urgency and accountability to advance projects efficientlyand compliantly.Opportunities will exist tocontribute to target validationand progression,collaborate across AbbVie sites,presentyour work,and mentor scientists.Wereexcited to see how you canhelpAbbViedeveloplife-changing psychiatric therapeutics for patients.

**Responsibilities**

- Proactively translatedepartment/projectteam scientific questions into well-designed experiments,utilizinginternal and external resources

- Exploremultipletechnicaloptions forapproach,quality, feasibility,efficiencyand present recommendations atprojectteam or group meetings

- Set upand carry outnovelmolecular and cellular assays/modelstosupport SAR and understanding of target biology in context of project team goals & transitions

- Document protocols and results in databases and electronic laboratory notebook, contributing to formal study reports per business need

- Upholdimpeccableresearch-related&corporate compliancestandards

- Collaborateacross the organization;Mentor/matrix managejunior scientists

**Qualifications**

- Bachelors Degree or equivalent education and typically 12+ years of experience, Masters Degree or equivalent education and typically 10+ years of experience, PhD and typically 4+ years of experience.

- Possess thorough theoretical and practical understanding of own scientific discipline.

- Effective writer and communicator of research or other regulatory materials.

**Desired Qualifications**

- Significant experiencewithrunning and interpretingpharmacological studies,humaniPSC-neuronculture,clonal cell lineculture, equipment/assayselectionand development

- Growth mindset with strong organizational, communication, and collaboration skills

- Demonstrated ability to learn and master new experimental techniques

- Attention to detail with ability to see big picture,multitask and work within timelines

- Pharmaceutical industrydrug discoveryexperience

- Experiencewith endpoints related toneurotransmitters, receptor signaling, trafficking, neuroplasticity, proteomics.

- Experience withmedium to high throughput technology and techniques such as electronic dispensing equipment/robotics,AlphaLISA, HTRF, ELISA, MSD, qPCR, capillary Western, FLIPR,kinetic/endpoint assays, high-contentimaging; engages vendors/reads manuals

- Ex vivo sampleassay design,processing,andanalysis experience

- Additional CNS iPSC-derived cell experience,encompassing multiple cell types

- Psychiatry therapeutic area experience

- FamiliarityleveragingAI tools to improve productivity

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

- The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this postingbased on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemayultimatelypaymore orless than the posted range. This range may bemodifiedin thefuture.

- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.

- This job is eligible toparticipatein our long-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission,incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company's sole andabsolutediscretion unless and until paidandmay bemodifiedat the Companys sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

Senior Scientist II, Molecular & Cellular Pharmacology, Discovery Psychiatry

The Broad Institute brings together a diverse group of individuals from across its partner institutions — undergraduate and graduate students, postdoctoral fellows, professional scientists, administrative professionals, and academic faculty.

The culture and environment at the Broad is designed to encourage creativity and to engage all participants, regardless of role or seniority, in the mission of the Institute. Within this setting, researchers are empowered — both intellectually and technically — to confront even the most difficult biomedical challenges.

The Institute’s organization is unique among biomedical research institutions. It encompasses three types of organizational units: core member laboratories, programs and platforms. Scientists within these units work closely together — and with other collaborators around the world — to tackle critical problems in human biology and disease.

Industry: Research Services
Company Size: 501-1,000 employees

Broad Institute of MIT and Harvard

RNA Sensor Design and High-Throughput Brain Cell Targeting The Chen Lab at the Broad Institute of MIT and Harvard seeks a highly motivated Research Scientist to independently lead a flagship, multi-year project focused on the design and implementation of RNA sensors for high-throughput brain cell targeting.

This role offers a rare opportunity to drive a cutting-edge research program at the intersection of pooled genetic screening, programmable molecular targeting, and next-generation delivery strategies for the nervous system. The successful candidate will have primary scientific ownership of the project, spanning conceptual design, experimental execution, data analysis, and collaboration. They will work closely with researchers across the Broad Institute and with external collaborators at partner universities, while also mentoring junior scientists and contributing to the broader intellectual direction of the lab. This position is ideal for a scientist who is excited to lead ambitious, technology-driven research with translational potential and broad impact across neuroscience and genomics.

CHARACTERISTIC DUTIES

-  Independently design and lead a research program to develop RNA sensor–based strategies for high-throughput, cell-type-specific targeting in the brain

-  Design, execute, and analyze pooled genetic and molecular screens to identify and optimize targeting strategies

-  Develop and optimize experimental pipelines spanning molecular engineering, delivery, screening, and readout

-  Integrate experimental results with computational analysis to guide iterative design and discovery

-  Collaborate with internal Broad Institute teams and external academic collaborators to advance shared scientific goals

-  Lead and mentor graduate students and research associates contributing to the project

-  Contribute to manuscripts, presentations, grant reports, and dissemination of new technologies

-  Support documentation, reproducibility, and potential intellectual property generation related to new methods

**Requirements**

-  Ph.D in molecular biology, bioengineering, neuroscience, genomics, or a related field

-  Demonstrated ability to independently lead complex research projects from conception through execution and publication

-  Strong experience with pooled genetic or molecular screens, programmable targeting strategies, or delivery technologies

-  Solid experimental background with comfort working across molecular, cellular, and systems-level approaches

-  Experience analyzing large-scale screening or genomics datasets; familiarity with computational or statistical analysis workflows is strongly preferred

-  Proven mentorship or team-leadership experience, or clear potential to supervise and guide junior scientists

-  Excellent communication, organizational, and collaborative skills in a fast-paced, interdisciplinary research environment

WORK ENVIRONMENT

The Broad Institute provides a vibrant, highly collaborative research environment with close ties to MIT, Harvard, and Harvard-affiliated hospitals across Boston. This position offers exceptional opportunities for scientific visibility, collaboration, and long-term impact, with work that will be broadly utilized and recognized across the global genomics and neuroscience research communities.

Pay Range: $88,000.00/yr - $124,000.00/yr

The expected base pay range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to, relevant skills, experience, education, qualifications, and other factors permissible by law.

At Broad, your base pay is just one part of a comprehensive total rewards package. From day one, this role offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits.

The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.

Should you need a reasonable accommodation to complete the application or interview process, please contact recruiting@broadinstitute.org for assistance.

Research Scientist I

At Merck, known as MSD outside of the United States and Canada, we are unified around our purpose: We use the power of leading-edge science to save and improve lives around the world. For more than 130 years, we have brought hope to humanity through the development of important medicines and vaccines. We aspire to be the premier research-intensive biopharmaceutical company in the world – and today, we are at the forefront of research to deliver innovative health solutions that advance the prevention and treatment of diseases in people and animals. We foster a diverse and inclusive global workforce and operate responsibly every day to enable a safe, sustainable and healthy future for all people and communities. For more information, visit www.merck.com. 

This site is intended for residents of the United States and Canada and their territories only. FLS: http://merck.us/3TKXNuZ

Industry: Pharmaceutical Manufacturing
Company Size: 10,001+ employees

Merck

**Job Description**

Our company is on a quest for cures and is committed to being the world’s premier, most research-intensive biopharmaceutical company. Today, we’re doubling down on this goal. Our company's Research Laboratories is a true scientific research facility of tomorrow and will take our company's leading discovery capabilities and world-class small molecule and biologics R&D expertise to create breakthrough science that radically changes the way we approach serious diseases.

The Data, AI & Genome Sciences department is looking for a passionate and talented computational biologist with deep expertise in image analysis to join our Translational Genome Analytics research team. In this role, you will apply AI/ML-based analytics to analyze large multi-scale and multi-omics imaging- and functional genomics-based datasets and closely collaborate with a cross-functional team of computational biologists, data scientists, and stakeholders in Discovery Research to drive target and biomarker discovery and drug development efforts. This role will support multiple therapeutic areas with a strong emphasis on Oncology.

The successful candidate will be a scientifically curious team player, strong communicator, and self-motivated learner with previous demonstrated expertise in computational image analysis, experience with multi-omics data integration and functional genomics assays, and an interest in leveraging AI/ML strategies to aid in our interpretation of complex biological data.

This role is based at our company's Research Labs in Cambridge, MA.

**In This Exciting Role, You Will**

- Contribute to multiple stages of drug discovery by interrogating high-throughput functional genomics and cellular profiling assays, including high-content imaging-based screens (e.g., optical pooled screens, cell painting, arrayed CRISPR assays), large-scale NGS-based screens (e.g., pooled CRISPR screens, Perturb-seq), and proteomic datasets.

- Translate biological questions into computational solutions by performing quantitative and rigorous statistical analysis on large-scale in vitro imaging datasets and clinical histopathology images for novel biomarker and target discovery.

- Leverage machine-learning approaches to integrate multiparametric image-derived features with high-throughput phenotypic screens.

- Closely collaborate with a broad variety of stakeholders, including molecular biologists, pathologists, bioinformaticians, and software engineers, and act as a proactive bridge and translator in cross-disciplinary communications.

- Employ best reproducible research and FAIR data practices to generate reusable analysis frameworks and reports to support target identification and validation efforts across therapeutic areas.

- Characterize novel targets coming from genetics, translational and disease pathway exploration, explore target engagement, research mechanisms of action, and provide functional validation of novel drug targets.

- Work with large internal and public biological data sets including Next Generation Sequencing (NGS) data (e.g. RNA-Seq, single cell RNA-Seq, spatial transcriptomics, WGS, CRISPR).

**Education Minimum Requirement**

- Ph.D. in Bioinformatics, Computational Biology, Computer Science, Biostatistics, Genetics, Immunology, Mathematics, Molecular Biology, Statistics, or related field and 3+ years of experience.

- Master degree in areas mentioned above with 7+ years of experience.

- Bachelor degree in above areas with 11+ years of experience.

- Experience must be post-degree. Can be a mix of relevant academic or industry experience.

**Required Experience And Skills**

- In-depth experience with analyzing high-content cellular and/or tissue imaging assays (e.g., Cell Profiler, scikit‑image, OpenCV, etc.).

- Deep experience with computational analysis (e.g., stain normalization, WSI-level classification, segmentation, etc.) of histopathology imaging (e.g., H&E/IHC whole slide images).

- Advanced programming skills with application in imaging (Python) and statistical analysis (R, tidyverse packages).

- Demonstrated ability to distill complex data into interpretable visualizations (e.g., ggplot2, plotly).

- Demonstrated experience with computational analysis and biological interpretation of diverse large-scale experimental datasets from NGS and arrayed screening.

- Skilled at integrating results generated from multiple omics data sources, and biological knowledge bases to customize analytical approaches for discovery research.

- Experience with AWS cloud computing infrastructure (e.g., S3, EBS, EC2, etc) and HPC Linux environments.

- Experience with version control systems, such as Git, and the ability to collaborate on code bases and adapt to and work with existing analytic frameworks.

- Passion for problem solving and continuous learning; applied both to understanding biology and solving technical challenges.

- Self-motivated, proactive, detail-oriented, and independent phenotype supported by references.

- Excellent verbal and written communication skills for cross-disciplinary collaboration.

- Previous experience as full-time computational biologist.

**Preferred Experience And Skills**

- Experience with optical pooled screening (OPS).

- Close familiarity with histology/microanatomy and microscopy readouts.

- Experience with digital pathology.

- Experience with using or developing pipelines with workflow orchestration tools such as Nextflow.

- Hands-on experience with applying AI/ML methods for analysis of image-based biological readouts.

- Interest in identifying novel applications of AI/ML strategies for biological target discovery.

- Experience with and understanding algorithms for DNA-seq, RNA-seq, single-cell RNA-seq and/or functional genomics data.

- Strong publication record.

#EligibleforERP

**Required Skills**

Amazon Web Services (AWS), Cell Imaging, Computational Biology, High Content Image Analysis, High Content Imaging, High Performance Computing (HPC), Histology, NGS Data Analysis, Omics, Python (Programming Language), RNA Sequencing, Tissue Histology, Whole Slide Imaging

**Preferred Skills**

Digital Pathology, Functional Genomics

Current Employees apply HERE

Current Contingent Workers apply HERE

**US And Puerto Rico Residents Only**

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

**Requirements**

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

**U.S. Hybrid Work Model**

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.

The salary range for this role is

$144,800.00 - $227,900.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

**San Francisco Residents Only: ** We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

**Los Angeles Residents Only: ** We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

**Search Firm Representatives Please Read Carefully**

Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

**Employee Status**

Regular

**Relocation:**

Domestic

**VISA Sponsorship**

Yes

**Travel Requirements**

No Travel Required

**Flexible Work Arrangements**

Hybrid

**Shift**

Not Indicated

**Valid Driving License**

No

**Hazardous Material(s)**

n/a

**Job Posting End Date**

05/15/2026

- A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

**Requisition ID: **R396052

Associate Principal Scientist, Computational Biologist and Image Analysis Expert

We are Sanofi, an innovative global healthcare company. We chase the miracles of science to improve people’s lives. 

Our team, across some 100 countries, is dedicated to transforming the practice of medicine by working to turn the impossible into the possible. We provide potentially life-changing treatment options and life-saving vaccine protection to millions of people globally, while putting sustainability and social responsibility at the center of our ambitions.

Interactions with this account must comply with the Terms: https://bit.ly/sanofi-terms

Industry: Fabrication de produits pharmaceutiques
Company Size: + de 10 000 employés

Sanofi

**Job Title: **Senior Clinical Research Director

**Location: **Cambridge, MA, Morristown, NJ

**About The Job**

Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions.

**About Sanofi**

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

**Main Responsibilities**

The role of the Senior CRD is to:

- Act as a mentor for other CRDs and Clinical Scientists on a same project/TA

- Collaborate with functions to ensure uniform, aligned operational approach (e.g harmonizing study documents, ES, protocols, etc). As relevant, within a project, ensure leadership, build consensus, coordinate action plans with other CRDs and stakeholders to resolve project-related study issues, anticipates potential issues (sharing lessons learned) across the project or study teams. He/she raises study or project-level issues to TA Heads, as relevant and shares relevant information within and beyond Project teams.

- Take on as necessary the CRD role:

- Provide medical expertise to the clinical studies (except select Exploratory Pharmacology studies) and/or registries (eg: protocol, Key Results, Clinical Study Report)

- Support other clinical development activities (e.g. pressure test and cluster feasibility, medical review and validation of clinical data, study risk assessment)

- Contribute to the clinical part of submission dossier for their projects: Common Technical Document for FDA & EMA submission, filing in Japan and China and answers to questions from health authorities

- Provide appropriate medical input & support for all activities related to clinical studies such as medical training, feasibility, medical review of data, medical information for the study team, medical advisors/Clinical Project Leaders from Clinical Study Units, and investigators

- Be the medical reference in the Clinical Study team, ensuring the medical relevance of the clinical data

- Interact with other CRDs in the project, Global Project Head, The PV Rep, Regulatory and other key functional reps

**Experience**

**About You**

- Understanding of pharmaceutical product development and life cycle management gained through ~4 years of clinical development and medical experience

- Excellent Scientific and medical / clinical expertise

- Excellent expertise in clinical development and methodology of clinical studies

- Excellent communication skills (verbal and written) for interactions across functional areas and for interactions with key regulatory agencies

- Demonstrated capability to challenge decision and status quo with a risk-management approach

- Ability to negotiate to ensure operational resources are available for continued clinical conduct

- Fluency in written and spoken English

- Excellent Teaching skills, demonstrated ability to assist and train others

- Ability to work within a matrix model

- International/ intercultural working skills

- Open-minded to apply new digital solutions

**Minimum Level Of Any Required Qualifications**

- MD or eqivalent (DO, MBBS)

- Specialization and training as a Rheumotologist

- At least 4 years in pharmaceutical industry or CRO, previous experience in late stage clinical development

- English fluent (spoken and written)

**Why Choose Us?**

- Bring the miracles of science to life alongside a supportive, future-focused team.

- Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or a lateral move, at home or internationally.

- Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

- Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs, and at least 14 weeks’ gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

#GD-SA

#vhd

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

Senior Clinical Research Director, I&I

**Job Description**

We are seeking a Scientist II who is passionate about developing complex in vitro microphysiological organ-on-chip systems (MPS) and bioprinted models for drug discovery and development. In this role, the scientist will perform hands-on experimentation and provide support to advance the team’s biofabrication efforts.

This position is based on-site in Cambridge, MA, supporting day-to-day laboratory workflows and assisting with model development within a collaborative research environment.

**Key Responsibilities**

- Support the biofabrication and maintenance of microphysiological systems and bioprinted models.

- Perform routine mammalian cell culture while maintaining a high level of aseptic technique.

- Prepare and handle hydrogels/ECM for use in 3D culture (MPS and bioprinted) platforms.

- Assist in immunofluorescence staining, imaging, and analysis workflows.

- Reconstitute, aliquot, and prepare reagents and media.

- Execute multi-step experimental protocols and workflows.

- Document experimental procedures, observations, and results in electronic lab notebook.

- Assist with inventory management, ordering, and general lab maintenance.

- Support both general and project-specific laboratory operations as project needs evolve.

- Collaborate across different functional teams/locations.

**Required Education: **High School Diploma or GED required. Bachelor’s Degree or Master’s Degree preferred. (~~B.S./B.A. in Bioengineering, Biology, Biomedical Engineering, Cell & Molecular Biology, Immunology, or a related field with minimum of 1 year of relevant experience or Master’s Degree)~~

**Required Experience And Skills**

- Minimum of 2 years of experience in mammalian cell culture and aseptic technique.

- Experience preparing and handling biomaterials or hydrogels for 3D culture applications.

- Experience working with MPS models, bioprinted platforms, or other 3D cell culture technologies.

- Familiarity with basic microscopy techniques for assessing cell health and experimental progress.

- Strong attention to detail, organizational skills, and accurate documentation practices.

- Demonstrated ability to execute experimental protocols and work with collaborators.

- Ability to work on-site, follow established protocols, and meet deadlines.

- Enthusiastic, self-motivated, and eager to learn new workflows.

**Preferred Experience And Skills**

- Experience with stem cell culture or differentiation workflows.

- Experience with stem cell-derived organoid models.

- Experience working with MIMETAS organ-on-chip, or similar high throughput, platform.

- Experience working in pharmaceutical drug discovery or development.

- Data analysis experience using Matlab, R, and/or Python.

- Experience with nucleofection.

#eligibleforerp

MSJR

**Required Skills**

3D Cell Culture, 3D Cultures, Aseptic Technique, Bioprinting, Bioproduction, Mammalian Cell Culture

**Preferred Skills**

Current Employees apply HERE

Current Contingent Workers apply HERE

**US And Puerto Rico Residents Only**

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

**Requirements**

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

**U.S. Hybrid Work Model**

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.

The salary range for this role is

$87,300.00 - $137,400.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

**San Francisco Residents Only: ** We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

**Los Angeles Residents Only: ** We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

**Search Firm Representatives Please Read Carefully**

Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

**Employee Status**

Regular

**Relocation:**

No relocation

**VISA Sponsorship**

No

**Travel Requirements**

10%

**Flexible Work Arrangements**

Not Applicable

**Shift**

Not Indicated

**Valid Driving License**

No

**Hazardous Material(s)**

N/A

**Job Posting End Date**

04/18/2026

- A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

**Requisition ID: **R390828

Specialist, 3DT Biofabrication Scientist (Cambridge, MA)

Pioneering Intelligence is an initiative of Flagship Pioneering harnessing artificial intelligence to accelerate innovation in the life sciences and beyond.  

Pioneering Intelligence is building unique AI/ML know-how to augment the capabilities of Flagship companies and enable bigger leaps in human health and sustainability, amplify the process of creating breakthrough innovations, and originate new platform companies that build on innovations in machine learning.

Industry: Software Development
Company Size: 11-50 employees

Pioneering Intelligence

**ABOUT PIONEERING INTELLIGENCE**

Pioneering Intelligence builds on Flagship Pioneering’s legacy of founding cutting-edge science and computational ventures, harnessing recent advances in AI, machine learning, and data to accelerate fundamental research and create a portfolio of AI-first companies. As part of Flagship’s integrated model of science, entrepreneurship, and capital, it transforms breakthrough ideas into world-changing companies, elevating the AI advances happening across the ecosystem in human health, sustainability, and beyond.

**Position Summary**

Flagship's Pioneering Intelligence seeks a VP AI Data Platform to lead the strategy and development of our AI-native data technologies. This platform leverages our unique breadth of portfolio company data in partnership with our AI scientists to return differentiated AI models and tools to the benefit of our portfolio companies. This leader partners with our scientific, technical, business, and legal colleagues to enable new AI capabilities while maintaining strong controls, trust, and compliance.

**Key Responsibilities**

- Own strategy and continued development of an AI-native data platform for benefits dozens of portfolio companies

- Deliver a product-minded and user-centered roadmap for the data platform

- Lead a high-performing technical team to implement the roadmap

- Build strategic co-development partnerships with external collaborators

- Work with leaders across the portfolio to ensure enthusiastic adoption of data platform tools

- Drives adoption across all wholly-owned portfolio companies

- Work with colleagues in Pioneering Intelligence to enable differentiated and innovative molecular models and agentic systems that leverage the data platform

- Ensures secure, compliant cross-company data governance

**Qualifications**

- Experience designing and delivering scalable data platforms used in machine learning contexts with sensitive proprietary data

- Experience balancing performance and cost of hardware and software vendor solutions with internal development efforts

- Strong knowledge of user-centered software product development

- Experience working with machine learning teams

- Demonstrated ability to understand concerns, align value, and enable shared outcomes across many stakeholders

- History of leading a high-functioning technical team of software and infrastructure engineers

- Experience with technical and legal data governance frameworks

- Communicates clearly with executive and nontechnical stakeholders

**Objectives**

- Adoption of the Flagship Data Exchange by all wholly-owned portfolio companies by June 2026

- Improve leverage of data for individual companies

- Enable sharing of new AI models trained on pan-portfolio data

- Enable well-governed cross-company data access

**ABOUT FLAGSHIP PIONEERING**

Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.

**We are an equal opportunity employer **. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

We recognize that great candidates often bring unique strengths **without fulfilling every qualification **. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background**and interest in Flagship.**

**Recruitment & Staffing Agencies **~~: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.~~

The salary range for this role is $275,000 - $365,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Pioneering Intelligence currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Pioneering Intelligence's good faith estimate as of the date of publication and may be modified in the future.

Vice President, Data Platform

We work at the frontier of programmable medicines. We power our bioplatform and product candidates by harnessing evolution and AI. We operate with purpose and urgency on behalf of people everywhere. We aim to generate life-changing impact for the world.

Industry: Biotechnology Research
Company Size: 51-200 employees

Sail Biomedicines

**About Sail:**

Sail Biomedicines is pioneering the integrative design and deployment of fully programmable medicines to transform patient care. Sail’s platform combines first-in-class programmable circular RNA technology (Endless RNA™ or eRNA), and an industry-leading platform of programmable nanoparticles, utilizing natural components, to unlock comprehensive programming of medicines for the first time. By leveraging cutting-edge eRNA and nanoparticle deployment technology, Sail is also making unparalleled use of AI techniques to identify and design fully programmable medicines that are potent, targeted, versatile, and tunable. Sail was founded by Flagship Pioneering.

**The Role:**

Sail Biomedicines is seeking a motivated Senior Research Associate / Scientist I to join our Vaccines, Immunoassay & Pharmacology team. This role will develop, optimize, and execute bioassays to characterize biological activity, mechanism, and immune responses for candidates enabled by Sail’s eRNA™ delivery platform, supporting in vivo PK/PD, toxicology, and translational decision-making.

This is a lab-based, onsite role with substantial hands-on experimental work, collaborative problem-solving, and close partnership with cross-functional teams. The ideal candidate brings strong experience in mammalian cell culture, flow cytometry, serology/immunoassays (e.g., ELISA/MSD), qPCR, and excellent scientific documentation. You will generate high-quality data, troubleshoot assays, and contribute to advancing Sail’s platform and pipeline.

**Responsibilities:**

Bioassay Development & Execution

- Develop, optimize, and execute cell-based and immunoassay workflows to support PK/PD, tox, and pharmacology readouts (e.g., potency/functional assays, biomarker assays, serology).

- Design and build multiparameter flow cytometry panels (marker selection, titrations, controls, compensation, gating strategy) for in vivo study sample analysis.

- Develop and run serology assays (e.g., binding antibody, neutralization/surrogate neutralization where applicable, cytokine/chemokine readouts) using ELISA, MSD, or related platforms.

- Qualify/validate assays as appropriate: establish accuracy/precision, sensitivity, range, robustness, and implement cross-study controls and reference standards.

- Own assay readiness: generate SOPs, templates, and training materials; ensure reproducibility and knowledge transfer.

Sample Operations & Study Support

- Coordinate sample receipt, accessioning, and tracking from internal studies and CRO-supported work; maintain chain-of-custody, storage conditions, and inventory.

- Perform sample processing (e.g., PBMC isolation, plasma/serum handling), ensuring consistency and biosafety compliance.

Data, Documentation & Collaboration

- Analyze, interpret, and summarize data; maintain rigorous records in ELN and associated databases.

- Present findings internally (lab meetings, project teams) with clear conclusions, limitations, and next steps.

- Partner with Biology, Analytics, and Computational/AI teams to define assay requirements, experimental design, and data structure/metadata.

- Contribute to reports, tech memos, and experiments that support IP and regulatory-facing documentation where relevant.

- Manage multiple concurrent experiments while maintaining high standards for lab safety, quality, and timelines.

**Required Qualifications:**

- B.S. or M.S. in Immunology, Bioengineering, Biochemistry, Molecular Biology, Chemistry, or related field.

- 2–4+ years relevant laboratory experience (industry preferred).

- Hands-on experience with flow cytometry and mammalian cell culture; experience with one or more of: PBMC isolation, primary cell handling, qPCR, ELISA/MSD, or related immunoassays.

- Working knowledge of assay development principles (controls, standard curves, variability, qualification/validation concepts).

- Strong experimental design and troubleshooting skills; able to optimize protocols and document changes clearly.

- Excellent organization and time management; able to prioritize and execute in a fast-paced environment.

- Strong written/verbal communication, including presenting data and writing concise summaries.

- Self-directed, collaborative, detail-oriented; demonstrates scientific curiosity and integrity.

**Preferred Qualifications:**

- Experience working with non-human primate (NHP) samples and associated biosafety practices.

- Basic working knowledge of biostatistics (e.g., variability, curve fitting, outlier handling, assay acceptance criteria).

- Experience with FlowJo, GraphPad Prism, and Microsoft Office (Excel/PowerPoint); familiarity with ELN best practices.

- Experience in a matrixed project environment supporting multiple programs.

Salary Range: $80,000 - $115,000

~~Sail Biomedicines is an Equal Opportunity Employer. Sail does not discriminate based on race, religion, color, sex, gender identity, sexual orientation, age, national origin, veteran status, or any other status protected under federal, state, or local law. ~~

Senior Research Associate/Associate Scientist

**Company Description**

**About AbbVie**

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube.

**Job Description**

The Discovery Neuroscience In Vivo Pharmacology group in Cambridge, Massachusetts, is seeking a highly skilled and self-motivated scientist to join a dynamic team supporting target validation and performing PK/PD studies. The ideal candidate has experience in independently running complex studies and in coordinating efforts between team members.

**Key Responsibilities**

- Responsible for design and implementation of in vivo testing of multispecific biologics, small molecules, and siRNAs to support projects in the areas of Alzheimers and Parkinsons disease

- Identify and solve technical problems independently, implement new assays and workflows

- Ensure consistency and quality of technical reports

- Collaborate with colleagues at various AbbVie sites

- Present original work internally across departments and at internal and external scientific conferences; may author or co-author peer-reviewed scientific papers or patents

**Qualifications**

**Minimum Qualifications:**

- Associate Scientist II Qualifications: Bachelors Degree, with typically 3 or more years experience OR Masters Degree (no additional experience)

- Scientist I Qualifications: BSc or MS in Neuroscience, Biological Sciences, Pharmacology, or related discipline with typically 5+ (BSc), or 3+ (MS) years of experience in industry and/or academia

- Proven track record of working in multidisciplinary in vivo pharmacology teams

- Experience with in vivo models of neurodegeneration, particularly with models of Alzheimers and Parkinsons Disease

- Proven track record in characterizing complex biotherapeutics in vivo (biologics, small molecules, siRNA)

- Excellent organizational skills and the ability to manage multiple projects simultaneously

- Demonstrated ability to collaborate effectively in a dynamic, cross-functional matrix environment

- Candidate must be a goal-oriented team player with excellent verbal and written communication skills and strong can-do attitude

**Preferred Qualifications**

- Background in receptor and / or transporter biology

- Background in brain barriers biology

- Prior team membership in the pharmaceutical / biotech industry

- Experience with ex vivo readouts including immunohistochemistry and biochemistry (ELISA, WB)

- Experience with image analysis

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

- The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at thetimeofthis posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographiclocation,andwemayultimatelypaymore or less than the posted range. This range may bemodifiedin thefuture.

- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.

- This job is eligible toparticipatein our short-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability ofanybonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company'ssoleandabsolutediscretion unless and until paid andmay bemodifiedat the Companys sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

Associate Scientist II/Scientist I - In Vivo Pharmacology

**Company Description**

**About AbbVie**

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube.

**Job Description**

The Advanced Cell Technologies, Screening, and Sequencing (ACTS) group in Discovery Neuroscience, in Cambridge, MA, is seeking a highly motivated scientist to join our team. This position is responsible for performing molecular biological research focused on target identification and validation, supporting early drug discovery efforts for neurodegenerative diseases and neuropsychiatric disorders. The ideal candidate will be collaborative, productive, and have strong hands-on experience with molecular biology techniques. The successful candidate will be expected to support multiple neuroscience pipeline projects that require both molecular and transcriptomic validation, as well as target identification for the exploratory projects.

**KeyResponsibilities**

- Support and assist with advanced molecular biology techniques including gene expression analysis and next-generation sequencing for target identification and validation research.

- Collaborate with colleagues at various AbbVie and external sites

- Analyze and summarize data and participate in the interpretation of results.

- Communicate with colleagues to discuss projects and experiment status and results.

- Operate and maintain laboratory equipment and manage supplies.

- Develop scientific and technical proficiency as necessary for project completion

**Qualifications**

- Associate Scientist II Qualifications: Bachelors Degree in Molecular Biology, Cell Biology, Neuroscience, or related field, with typically 3 or more years experience or Masters Degree (no additional experience)

- Scientist I Qualifications: Bachelors Degree in Molecular Biology, Cell Biology, Neuroscience, or related field, with typically 5 or more years experience or Masters Degree 2 or more years' experience

- Strong skillset in molecular biology techniques (RNA/DNA isolation and QC).

- Experience with medium-throughput screening (qPCR and ddPCR).

- Experience with next-generation sequencing (bulk RNA-seq and sc/snRNA-seq)

- Ability to independently execute and analyze experiments and troubleshoot technical challenges

**Preferred Qualifications**

- Experience with automated laboratory system (KingFisher Flex and Biomek i7 workstation).

- Experience in working in multidisciplinary teams, and in external collaboration.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

- The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemay ultimatelypay more or less than the posted range. This range may be modified in thefuture.

- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.

- This job is eligible to participate in our short-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company's sole andabsolutediscretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

Scientist I/Associate Scientist II, Transcriptional Profiling

We’re celebrating over 175 years of daring scientific innovation—and we’re not done yet. Let’s outdo yesterday. Protect your health at PfizerForAll.com
 
For additional information on our guidelines, please visit  http://www.pfizer.com/community-guidelines

Industry: Pharmaceutical Manufacturing
Company Size: 10,001+ employees

Pfizer

As the world’s leading pharmaceutical company, Pfizer is in the unique position of having some of the largest and most complex chemical and biological data sets available anywhere. The computational absorption, distribution, metabolism and excretion (cADME) group at Pfizer is responsible for maximizing the value of ADME, Safety, and Pharmacology data generated to support drug discovery project teams. As an **AI Cheminformatics Scientist **, you will apply data-driven approaches to drug discovery-focused chemical and biological problems, apply and develop AI/ML models for molecular property prediction, and analyze and optimize hit to lead and lead optimization strategies from our proprietary knowledge base. You will work closely with both the internal product team and external partners to maximize the value of our data.

**Role Responsibilities**

- Drive scientific and technical advancement in PDM’s AI and cheminformatics capabilities by developing and delivering robust, validated workflows and algorithms that directly support drug discovery. Success will be measured by the implementation of effective AI-driven solutions, demonstrated impact on project outcomes, and the publication or presentation of results.

- Design, build, and deploy innovative cheminformatics and AI workflows for small molecule discovery, with clear deliverables including prioritized compound lists, well-defined chemical libraries, and actionable structure-activity relationship analyses.

- Collaborate closely with medicinal chemists, biologists, and data scientists to integrate computational approaches into experimental and analytical workflows. Success in this area will be reflected by joint project milestones achieved, co-authored publications, and the creation of interdisciplinary solutions that accelerate drug discovery.

- Continuously monitor and evaluate emerging advances in AI, cheminformatics, and computational drug discovery, proactively leading the adoption of promising new methodologies. Contributions will include piloting novel techniques, leading internal workshops or training sessions, and helping set strategic directions for technology adoption.

- Collaborate with cross-functional teams—including medicinal chemists, biologists, and data scientists—to integrate computational solutions into drug discovery workflows.

- Develop novel algorithms and analytical strategies tailored to Pfizer’s proprietary datasets and key scientific questions, with measurable outcomes such as validated models, software tools, and contributions to scientific literature or patent filings.

**Basic Qualifications**

-  A Ph.D. or Master’s degree in Cheminformatics, Computational Chemistry, Bioinformatics, Data Science, or a closely related field is required.

- 8+ years of experience working in drug discovery within the pharmaceutical or biotechnology industry.

- Demonstrated expertise in applying AI methods to medicinal chemistry or cheminformatics challenges, including work with molecular representations, chemical fingerprints, QSAR, generative models, transformer architectures, pretraining strategies, property prediction, virtual screening, and ADMET modeling.

- Strong proficiency in Python, with hands-on experience using cheminformatics libraries and tools such as RDKit, OpenEye, DeepChem, InChI, and SMILES/SMARTS.

- Proven track record of creatively applying computational techniques to address problems relevant to pharmaceutical research and development.

- Ability to communicate effectively, collaborate with diverse teams, and deliver results in a fast-paced environment while managing multiple priorities.

- Experience working within a structured, collaborative data and software development environment, such as using version control systems like Git.

Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

**Additional Information**

Relocation support available

Work Location Assignment: Hybrid

The annual base salary for this position ranges from $124,400.00 to $207,400.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

**Sunshine Act**

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

**EEO & Employment Eligibility**

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.

Research and Development

Senior Principal AI/ML Cheminformatics Scientist

Novartis is an innovative medicines company. Every day, working to reimagine medicine to improve and extend people’s lives so that patients, healthcare professionals and societies are empowered in the face of serious disease. Our medicines reach more than 250 million people worldwide. 

Find out more at https://www.novartis.com 

See our community guidelines: https://go.novartis.social/3Nboxki

Industry: Arzneimittelherstellung
Company Size: 10.001+ Beschäftigte

Novartis

**Summary**

The Clinical Sciences Associate Director may provide clinical leadership and strategic input for all clinical deliverables across assigned indication/program or studies within BR. May act as Focus/Disease/Platform Area Lead. May function as a Core Project Team member for assigned projects to drive the Research-Development- Commercial (R-D-C) continuum. May co-lead project clinical sub-team and reports study/project progress and issues with their resolution plan to project teams and stakeholders. Directs early stages of study design and operational plans

Location: Cambridge

**About The Role**

**Key Responsibilities:**

- Study Leader and/or Clinical Scientist for predominantly high complexity, global studies and may provide additional Clinical Sciences support to high priority, high complexity, global studies.

- Independently lead the clinical protocol development process in collaboration with the Medical Lead and other line functions; responsible author for clinical protocols, amendments, etc.; contribute to the medical/scientific input given for the development of study-related documents and processes which reside in other line functions; contribute to the development of clinical sections of study-level regulatory documents.

- Lead development of strategic and scientific input into study concept, feasibility, and ability to execute; develop and implement study-level operational execution plan in partnership with key cross functional partners, if applicable.

- Collaborate with key cross functional partners to identify and select strategic and high performing sites to ensure recruitment commitments are met.

- Lead a global cross functional Clinical Trial Team (CTT) to ensure all trial deliverables are met; set stretch goals, promote realistic planning and timelines, and presents actionable alternatives to accelerate timelines.

- Partner with line functions to gain input and alignment and manages internal and external stakeholder expectations.

- Lead the ongoing medical/scientific review of clinical trial data across assigned studies in collaboration with the medical expert and key line functions, and partners on data analysis and data interpretation, including safety trend analysis, signal detection, development of first interpretable results, reporting clinical study results in Clinical Study Report (CSR), and internal/external publications.

- Prepare and lead dose escalation meetings with investigators. Coordinate the real time availability of quality clinical trial data, to provide consolidated information for dose escalation meetings and Phase II data reviews with relevant stakeholders.

- Proactively lead risk mitigation discussions, risk management and implementation at the trial level.

- Responsible and accountable for forecasting and managing overall study budget(s) in collaboration with key partners.

- Collaborate with key partners to set vendor strategy and timelines for assigned studies.

- Responsible for implementation of best practices and standards for trial management, including sharing lessons learned. Represent group on initiatives; may serve as Subject Matter Expert

- Contribute to talent and career development of staff. In collaboration with the relevant manager, contribute to hiring/interview/onboarding and mentoring process for new hires.

- Line management of assigned associates. Accountable for talent attraction and retention; supporting career growth and development.

- May deputize for his/her manager upon request.

**Essential Requirements**

- Bachelors in life science/healthcare required; Advanced degree or equivalent education/degree in life sciences/ healthcare preferred (PhD/MD/PharmD/ Masters).

- 8+ years’ experience in clinical trials/development.

- Demonstrates high learning agility in multiple therapeutic areas.

- Demonstrated knowledge and ability to confidently drive complex collaborations through unpredictable circumstances and higher paced changes.

- Demonstrates leadership and influence by creating a positive work environment by inspiring and encouraging mutual respect, instills innovation and accountability on a functional and trial level.

- Strong interpersonal skills with a proven track record of successfully interacting with and influencing with a wide range of people, building strong positive relationships.

- Demonstrates strong organizational awareness and stakeholder management skills.

- Demonstrate strong tolerance for ambiguity, willingness to adapt, and willingness to speak-up and challenge.

The salary for this position is expected to range between $152,600 and $283,400 per year.

The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.

Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.

US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.

To learn more about the culture, rewards and benefits we offer our people click here.

**Why Novartis: ** Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture

**Benefits and Rewards: ** Learn about all the ways we’ll help you thrive personally and professionally.

Read our handbook (PDF 30 MB)

**EEO Statement**

The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.

**Accessibility & Reasonable Accommodations**

The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to [email protected] or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Clinical Sciences Associate Director

At State Street, we partner with institutional investors all over the world to provide comprehensive financial services, including investment management, investment research and trading, and investment servicing. Whether you are an asset manager, asset owner, alternative asset manager, insurance company, pension fund or official institution, you can rely on us to be focused on your challenges. We are committed to doing what it takes to help you perform better — now and in the future.

Industry: Financial Services
Company Size: 10,001+ employees

State Street

**Who We Are Looking For:**

The AI and Trading Analytics Researcher (Assistant Vice President) will be a member of the AI and Trading Analytics team within State Street Associates (SSA), the quantitative research division of State Street Markets. The team conducts quantitative research on financial markets, developing systematic trading models, alpha signals, and analytics that support Markets trading businesses (FX, Financing Solutions, etc..). They will also contribute to the development of an agentic AI platform, empowering trading and sales desks to derive insights more efficiently.

The AI and Trading Analytics team operates at the intersection of quantitative research, markets, and technology. Team members work in a hybrid model, spending part of the week embedded on the Markets trading floor at One Congress (OCB) in Boston and part of the week at SSA’s research offices in Cambridge. This structure enables close, continuous collaboration with traders while situating the work within a rigorous research environment.

State Street Associates provides the broader research platform in which the team operates. SSA is a long‑standing partnership between State Street Markets and leading academics, focused on proprietary indicators and novel empirical methods. Within this context, the AI and Trading Analytics team collaborates closely with SSA researchers and academic partners, applying statistical and ML techniques to extend core research insights into systematic strategies and predictive signals for internal trading desks.

Working with senior researchers, traders, and technology partners, the AI and Trading Analytics Researcher contributes to end‑to‑end research, from idea generation and model development through validation and implementation. The role emphasizes robust, interpretable, and scalable approaches that bridge academic research, empirical market analysis, and real‑world trading application.

**Why this role is important to us**

The team you will be joining is a part of State Street Markets. As a leading provider of trading and lending solutions to the world’s institutional investors, we deliver the industry’s most innovative platforms, financing and portfolio solutions. Our capabilities are backed by proprietary, high-value research, insights and indicators that power clients’ investment decisions, accelerate performance and help investors stay ahead of shifting markets. Across our comprehensive set of solutions – data-driven macro market intelligence that give an information advantage; client-first platforms and tools that redefine trading; financing solutions that streamline liquidity access; and portfolio solutions designed to help achieve peak performance – we deliver a breakthrough edge to drive business success.

**What You Will Be Responsible For**

As a AI and Trading Analytics Researcher, AVP you will:

**Key Responsibilities**

- Design and test quantitative models, trading analytics, and alpha signals to address specific Markets business needs.

- Work closely with SSA research experts and academic collaborators to incorporate advanced research ideas into practical internal trading analytics and models.

- Apply statistical methods and ML to extract insights from large financial datasets and proprietary SSA research indicators.

- Develop research code, AI-based analytical tools, and model specifications in Python, Matlab, SQL, supporting implementation and reuse.

- Collaborate directly with traders and subject matter experts while embedded on the trading floor to prototype ideas and refine models.

- Translate research findings into internal tools, systematic indicators, and client‑facing materials.

- Communicate results clearly through written analysis and presentations for internal and external audiences.

**What We Value:**

We are looking for highly motivated candidates with exceptional quantitative skills and a desire to develop and implement new research ideas in a practical setting.

**Education & Preferred Qualifications:**

- Advanced degree and/or proven experience in a quantitative field such as finance, economics, mathematics, computer science, or a related discipline.

- 3-5 years’ work experience in investment management, investment research, data science, or a similar field involving quantitative techniques for data and analysis.

- Strong familiarity with theoretical and practical concepts in data analytics for investing, statistical analysis, time series forecasting, classical statistics, and machine learning / AI.

- Strong familiarity with concepts in investment management, asset allocation, risk management, and investment strategy design.

- Highly proficient coding skills (Python preferred) and attention to detail.

- Highly effective communication skills and ability to collaborate successfully.

**About State Street**

**What we do **. State Street is one of the largest custodian banks, asset managers and asset intelligence companies in the world. From technology to product innovation, we’re making our mark on the financial services industry. For more than two centuries, we’ve been helping our clients safeguard and steward the investments of millions of people. We provide investment servicing, data & analytics, investment research & trading and investment management to institutional clients.

**Work, Live and Grow. ** We make all efforts to create a great work environment. Our benefits packages are competitive and comprehensive. Details vary by location, but you may expect generous medical care, insurance and savings plans, among other perks. You’ll have access to flexible Work Programs to help you match your needs. And our wealth of development programs and educational support will help you reach your full potential.

**Inclusion, Diversity and Social Responsibility **. We truly believe our employees’ diverse backgrounds, experiences and perspectives are a powerful contributor to creating an inclusive environment where everyone can thrive and reach their maximum potential while adding value to both our organization and our clients. We warmly welcome candidates of diverse origin, background, ability, age, sexual orientation, gender identity and personality. Another fundamental value at State Street is active engagement with our communities around the world, both as a partner and a leader. You will have tools to help balance your professional and personal life, paid volunteer days, matching gift programs and access to employee networks that help you stay connected to what matters to you.

State Street is an equal opportunity and affirmative action employer.

Discover more at StateStreet.com/careers

**Salary Range:**

$175,000 - $175,000 Annual

The range quoted above applies to the role in the primary location specified. If the candidate would ultimately work outside of the primary location above, the applicable range could differ.

~~Employees are eligible to participate in State Street’s comprehensive benefits program, which includes: our retirement savings plan (401K) with company match; insurance coverage including basic life, medical, dental, vision, long-term disability, and other optional additional coverages; paid-time off including vacation, sick leave, short term disability, and family care responsibilities; access to our Employee Assistance Program; incentive compensation including eligibility for annual performance-based awards (excluding certain sales roles subject to sales incentive plans); and, eligibility for certain tax advantaged savings plans.~~

~~For a full overview, visit ~~~~https://hrportal.ehr.com/statestreet/Home ~~~~.~~

**About State Street**

Across the globe, institutional investors rely on us to help them manage risk, respond to challenges, and drive performance and profitability. We keep our clients at the heart of everything we do, and smart, engaged employees are essential to our continued success.

We are committed to fostering an environment where every employee feels valued and empowered to reach their full potential. As an essential partner in our shared success, you’ll benefit from inclusive development opportunities, flexible work-life support, paid volunteer days, and vibrant employee networks that keep you connected to what matters most. Join us in shaping the future.

As an Equal Opportunity Employer, we consider all qualified applicants for all positions without regard to race, creed, color, religion, national origin, ancestry, ethnicity, age, disability, genetic information, sex, sexual orientation, gender identity or expression, citizenship, marital status, domestic partnership or civil union status, familial status, military and veteran status, and other characteristics protected by applicable law.

Discover more information on jobs at StateStreet.com/careers

Read our CEO Statement

**Job Application Disclosure:**

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Job ID: R-785694

AI and Trading Analytics Researcher, AVP

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