Developing a seamless bioelectronic interface.

Industry: Nanotechnology Research
Company Size: 11-50 employees

Axoft

Savvy Admin PROD

**Summary**

Axoft is building the most advanced infrastructure for implantable brain-machine interfaces. Our mission is to enable long-term stable and ultra-high bandwidth communication with the brain, opening new therapies and treatments against neurological disorders and physical disabilities. We have bridged the gap between electronic and biological materials to create the softest, nanofabricated brain implants in the world.

**Position Overview**

Axoft developed the most advanced high-performance soft materials for hardware-biology interfaces. Our Materials platform continues to expand to new applications, and the team continuously develops new polymers through custom synthesis to meet demanding mechanical, processing, and biostability requirements. We are looking for individuals who deliver results, solve hard problems with clarity, and bring strong technical and interpersonal competence.

As a **Polymer Chemist **, you will contribute to the production of Fleuron polymers, and drive synthesis and development of new polymers for Axoft’s next-generation applications.

**Your Responsibilities**

- Plan and execute routine and advanced polymer synthesis work with minimal supervision.

- Analyze and document experiments, communicating findings clearly.

- Draft work instructions, maintain quality documentation, and support the QMS in alignment with ISO-9001, including production engineering documentation and process workflows.

- Manage chemical inventory, storage, and safe disposal.

- Handle multiple lab tasks efficiently under time constraints.

- Candidate routinely practices good chemical hygiene and adheres to safety protocols.

- Take on complex synthesis challenges, including molecular weight control, end-group tuning, reproducibility, and new macromolecular designs, with rigor and persistence.

**Key Qualifications**

- PhD in Chemistry, Materials Science, or a related field.

- Hands-on, effective, and independent in a chemistry lab setting.

- Skilled with organic solvents and chemical reagents, precise execution of synthesis protocols, and accurate documentation.

- Proficient in handling air- and moisture-sensitive compounds.

- Experience with synthesis of polyurethanes with understanding of structure-property correlation.

- Experience with various crosslinking chemistries

- Expertise with NMR characterization of small molecules and polymers.

**Preferred Qualifications**

- 3+ years of industry experience in polymer R&D or medical polymer industry.

- Experience in scaling up polymer synthesis schemes.

- Experience with quality assurance related to GMP, ISO-9001 and ISO-13485 manufacturing principles.

- Experience in Design of Experiments, Root Cause Analysis and related data-driven engineering tools from Lean Six Sigma methodology.

- Experience in designing / testing photopolymers for bioMEMS

**What We Offer**

- An opportunity to work with a team of experts on one of the most exciting problems in the world and change lives

- Career growth opportunities that fit your potential

- Flexible paid time off

- 401k

- Dental, vision and health insurance (100% covered)

Axoft’s ideal team members are people who seek fast paced, evolving work with bright, thoughtful, and dedicated teammates. We seek and embrace challenges, and we are focused on improving the health and well-being of people. We believe in producing the highest quality work, and we hold ourselves and each other to high standards of integrity, accountability, growth, and trust.

Axoft provides equal opportunity in all our employment practices to all qualified employees and applicants without regard to race, color, religion, gender, national origin, age, disability, marital status, military status, genetic information or any other category protected by federal, state and local laws. This policy applies to all aspects of the employment relationship, including recruitment, hiring, compensation, promotion, transfer, disciplinary action, layoff, return from layoff, training and social, and recreational programs. All such employment decisions will be made without unlawfully discriminating on any prohibited basis.

Polymer Chemist

The Broad Institute brings together a diverse group of individuals from across its partner institutions — undergraduate and graduate students, postdoctoral fellows, professional scientists, administrative professionals, and academic faculty.

The culture and environment at the Broad is designed to encourage creativity and to engage all participants, regardless of role or seniority, in the mission of the Institute. Within this setting, researchers are empowered — both intellectually and technically — to confront even the most difficult biomedical challenges.

The Institute’s organization is unique among biomedical research institutions. It encompasses three types of organizational units: core member laboratories, programs and platforms. Scientists within these units work closely together — and with other collaborators around the world — to tackle critical problems in human biology and disease.

Industry: Research Services
Company Size: 501-1,000 employees

Broad Institute of MIT and Harvard

RNA Sensor Design and High-Throughput Brain Cell Targeting The Chen Lab at the Broad Institute of MIT and Harvard seeks a highly motivated Research Scientist to independently lead a flagship, multi-year project focused on the design and implementation of RNA sensors for high-throughput brain cell targeting.

This role offers a rare opportunity to drive a cutting-edge research program at the intersection of pooled genetic screening, programmable molecular targeting, and next-generation delivery strategies for the nervous system. The successful candidate will have primary scientific ownership of the project, spanning conceptual design, experimental execution, data analysis, and collaboration. They will work closely with researchers across the Broad Institute and with external collaborators at partner universities, while also mentoring junior scientists and contributing to the broader intellectual direction of the lab. This position is ideal for a scientist who is excited to lead ambitious, technology-driven research with translational potential and broad impact across neuroscience and genomics.

CHARACTERISTIC DUTIES

-  Independently design and lead a research program to develop RNA sensor–based strategies for high-throughput, cell-type-specific targeting in the brain

-  Design, execute, and analyze pooled genetic and molecular screens to identify and optimize targeting strategies

-  Develop and optimize experimental pipelines spanning molecular engineering, delivery, screening, and readout

-  Integrate experimental results with computational analysis to guide iterative design and discovery

-  Collaborate with internal Broad Institute teams and external academic collaborators to advance shared scientific goals

-  Lead and mentor graduate students and research associates contributing to the project

-  Contribute to manuscripts, presentations, grant reports, and dissemination of new technologies

-  Support documentation, reproducibility, and potential intellectual property generation related to new methods

**Requirements**

-  Ph.D in molecular biology, bioengineering, neuroscience, genomics, or a related field

-  Demonstrated ability to independently lead complex research projects from conception through execution and publication

-  Strong experience with pooled genetic or molecular screens, programmable targeting strategies, or delivery technologies

-  Solid experimental background with comfort working across molecular, cellular, and systems-level approaches

-  Experience analyzing large-scale screening or genomics datasets; familiarity with computational or statistical analysis workflows is strongly preferred

-  Proven mentorship or team-leadership experience, or clear potential to supervise and guide junior scientists

-  Excellent communication, organizational, and collaborative skills in a fast-paced, interdisciplinary research environment

WORK ENVIRONMENT

The Broad Institute provides a vibrant, highly collaborative research environment with close ties to MIT, Harvard, and Harvard-affiliated hospitals across Boston. This position offers exceptional opportunities for scientific visibility, collaboration, and long-term impact, with work that will be broadly utilized and recognized across the global genomics and neuroscience research communities.

Pay Range: $88,000.00/yr - $124,000.00/yr

The expected base pay range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to, relevant skills, experience, education, qualifications, and other factors permissible by law.

At Broad, your base pay is just one part of a comprehensive total rewards package. From day one, this role offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits.

The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.

Should you need a reasonable accommodation to complete the application or interview process, please contact recruiting@broadinstitute.org for assistance.

Research Scientist I

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